Browsing by Author Zhang, Xu Dong

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Issue DateTitleAuthor(s)Citation
2011Adaptation to ER Stress as a Mechanism of Resistance of Melanoma to TreatmentHersey, Peter; Dong, Li; Jiang, Chen Chen; Tay, Kwang Hong; Tseng, Hsin-Yi; Zhang, Xu Dong; Northern Clinical School: SurgeryAdaptation to ER Stress as a Mechanism of Resistance of Melanoma to Treatment in Current Management of Malignant Melanoma, InTech Publishers, 2011, pp. 253-274
2013Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in MelanomaBecker, Therese; Carlino, Matteo; Gowrishankar, Kavitha; Kefford, Richard (Rick); Long, Georgina; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Snoyman, Stephanie; Saunders, Catherine; Zhang, Xu Dong; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteAntiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma, Molecular Cancer Therapeutics, vol.12, 7, 2013,pp 1332-1342
2010Apoptosis of Human Melanoma Cells Induced by Inhibition of B-RAFV600E Involves Preferential Splicing of BimSBecker, Therese; Rizos, Helen; Croft, A.; Hersey, Peter; Jiang, Chen Chen; Lai, F; Liu, H.; Tay, KH; Thorne, R F; Yang, F.; Zhang, Xu Dong; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteApoptosis of Human Melanoma Cells Induced by Inhibition of B-RAFV600E Involves Preferential Splicing of BimS, Cell Death & Disease, vol.1, 9,pp e69-1-e69-14
2013The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistanceGallagher, Stuart; Haass, Nikolas; Hersey, Peter; Mijatov, Branka; Lai, Fritz; Mohana-Kumara, Nethia; Wroblewski, David; Zhang, Xu Dong; Western Clinical School: Medicine (Westmead); Central Clinical School: Centenary Institute; Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteThe BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance, Carcinogenesis, vol.34, 2, 2013,pp 237-247
2010Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIP(L) from degradation by the E3 ligase itch in human melanoma cellsChristopherson, Richard; Yang, E.; Dong, L.; Hersey, Peter; Jiang, Chen Chen; Liu, H.; Tay, KH; Thorne, R F; Tseng, H-Y; Yang, F.; Zhang, Xu Dong; School of Molecular Bioscience; School of Molecular BioscienceCystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIP(L) from degradation by the E3 ligase itch in human melanoma cells, Cell Death & Differentiation, vol.17, 8,pp 1354-1367
2011The emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancersHersey, Peter; Scolyer, Richard; Wilmott, James; Zhang, Xu Dong; Medicine Faculty Office; Central Clinical School: Pathology; School of Medical Sciences: PathologyThe emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancers, Pathology, vol.43, 6, 2011,pp 657-671
2015ER stress-induced autophagy in melanomaDong, Qihan; Yao, Mu; Meng, Xiao-Xiao; Xu, Hong-Xi; Zhang, Xu Dong; Central Clinical School: Medicine; Central Clinical School: MedicineER stress-induced autophagy in melanoma, Clinical and Experimental Pharmacology and Physiology, vol.42, 8, 2015,pp 811-816
2012Evidence for upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitorsHersey, Peter; Jiang, Chen Chen; Lai, Fritz; Zhang, Xu Dong; Farrelly, Margaret L.; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling InstituteEvidence for upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitors, Melanoma Research: a journal for basic, translational and clinical research in melanoma, vol.22, 3, 2012,pp 244-251
2009Expression of glucose-regulated stress protein GRP78 is related to progression of melanomaLee, Cheok; McCarthy, Stanley; Scolyer, Richard; Thompson, John; Cooper, Wendy A.; Hersey, Peter; Zhang, Xu Dong; Zhuang, L.; Central Clinical School: Medicine; Central Clinical School: Inst. of Anatomical Pathology RPAH; Central Clinical School: Pathology; Central Clinical School: SurgeryExpression of glucose-regulated stress protein GRP78 is related to progression of melanoma, Histopathology, vol.54, 4,pp 462-470
2012Histone Deacetylases (HDACs) as Mediators of Resistance to Apoptosis in Melanoma and as Targets for Combination Therapy with Selective BRAF InhibitorsGallagher, Stuart; Hersey, Peter; Jin, Lei; Mijatov, Branka; Lai, Fritz; Zhang, Xu Dong; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium InstituteHistone Deacetylases (HDACs) as Mediators of Resistance to Apoptosis in Melanoma and as Targets for Combination Therapy with Selective BRAF Inhibitors, Advances in Pharmacology, vol.65, N/A, 2012,pp 27-43
2010Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteinsMcCarthy, Stanley; Murali, Rajmohan; Scolyer, Richard; Thompson, John; Hersey, Peter; Zhang, Xu Dong; Zhuang, L.; Central Clinical School: Inst. of Anatomical Pathology RPAH; Central Clinical School: Pathology; Central Clinical School: Pathology; Central Clinical School: SurgeryLactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins, Modern pathology, vol.23, 1,pp 45-53
2014Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanomaHersey, Peter; de Bock, C E; Geng, Xin Yan; Molloy, T; Oliveira, Camila; Sadeqzadeh, Elham; Thorne, Rick Francis; Zhang, Xu Dong; Northern Clinical School: SurgeryMacrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma, BMC Cancer, vol.14, N/A, 2014,pp 1-14
2007Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanomaLee, Cheok; McCarthy, Stanley; Scolyer, Richard; Thompson, John; Zhuang, Liqing; Hersey, Peter; Zhang, Xu Dong; School of Medical Sciences: Pathology; Central Clinical School: Inst. of Anatomical Pathology RPAH; Central Clinical School: Pathology; Central Clinical School: Surgery; Dermatology Research Foundat.Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma, Modern pathology, vol.20,(4),2007,pp 416-426
2013MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancerJin, Lei; Feng, Y; Guo, Sutang; Guo, X Y; Jiang, Chen Chen; Li, Y P; Thorne, Rick; Tseng, Hsin-Yi; Wang, ChunYan; Wang, F H; Wang, G P; Yang, R H; Zhang, Xu Dong; Northern Clinical School: Kolling InstituteMicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer, Oncogene, vol.32, 15, 2013,pp 1910-1920
2012Modulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737Haass, Nikolas; Weninger, Wolfgang; Allen, John D; Hersey, Peter; Huang, David; Kumaran - Mohana, Nethia; Lau, Diana; Lucas, Keryn; Zhang, Xu Dong; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteModulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737, Clinical Cancer Research, vol.18, 3, 2012,pp 783-795
2014Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cellsScolyer, Richard; Wilmott, James; Guo, Su T; Jiang, Chen Chen; Jin, Lei; Lai, Fritz; Liu, Xiao Ying; Liu, Yi Lun; Luan, Qi; Tseng, Hsin-Yi; Yan, Xu Guang; Zhang, Xu Dong; Central Clinical School: Pathology; Central Clinical School: SurgeryNoxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells, Oncotarget, vol.5, 22, 2014,pp 11237-11251
2014Oncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum StressBoyd, Suzanah; Hersey, Peter; Rizos, Helen; Croft, Amanda; Guo, Su T; Jiang, Chen Chen; Jin, Lei; Lai, Fritz; Tay, Kwang Hong; Tseng, Hsin-Yi; Zhang, Xu Dong; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteOncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum Stress, Journal of Investigative Dermatology, vol.134, 2, 2014,pp 488-497
2006Progression in melanoma is associated with decreased expression of death receptors for tumor necrosis factor-related apoptosis-inducing ligand.Hersey, Peter; Lee, Cheok; McCarthy, Stanley; Scolyer, Richard; Thompson, John; Zhuang, Liqing; Screaton, Gavin; Zhang, Xu Dong; Medicine Faculty Office; Central Clinical School: Medicine; Central Clinical School: Inst. of Anatomical Pathology RPAH; Central Clinical School: Pathology; Central Clinical School: Surgery; Dermatology Research Foundat.Progression in melanoma is associated with decreased expression of death receptors for tumor necrosis factor-related apoptosis-inducing ligand., Human Pathology, vol.37,(10),2006,pp 1286-1294
2013Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in MelanomaHersey, Peter; Ashton, Katie A; Avery-Kiejda, Kelly A; Bowden, Nikola; Braye, Stephen; Budden, Timothy; Davey, Ryan; Murray, Heather; Scott, Rodney J.; Vilain, Ricardo; Zhang, Xu Dong; Northern Clinical School: SurgeryRegulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma, PLoS One, vol.8, 8, 2013,pp 1-8
2015RIP1 Kinase Is an Oncogenic Driver in MelanomaScolyer, Richard; Wilmott, James; Croft, Amanda; Guo, Sutang; Jiang, Chen Chen; Jin, Lei; Lai, Fritz; Liu, Xiao Ying; Tseng, Hsin-Yi; Wang, ChunYan; Yan, Xu Guang; Zhang, Xu Dong; Central Clinical School: Pathology; Central Clinical School: SurgeryRIP1 Kinase Is an Oncogenic Driver in Melanoma, Cancer Research, vol.75, 8, 2015,pp 1736-1748