Browsing by Author Wright, Lesley

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Issue DateTitleAuthor(s)Citation
2006Application of proton nuclear magnetic resonance spectroscopy to the study of Cryptococcus and cryptococcosis.Himmelreich, Uwe; Sorrell, Tania; Wright, Lesley; Malik, Richard; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteApplication of proton nuclear magnetic resonance spectroscopy to the study of Cryptococcus and cryptococcosis., F E M S Yeast Research, vol.6,(4),2006,pp 558-566
2007Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrityDjordjevic, Julianne; Larsen, Michelle; Siafakas, Rosemary; Sorrell, Tania; Wilson, Christabel; Wright, Lesley; Boadle, Ross; Williamson, Peter R.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Infectious Diseases; Western Clinical School: Westmead Millennium Institute; Infectious Diseases; Western Clinical School: Westmead Millennium InstituteCell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrity, Journal of Biological Chemistry, vol.282,(52),2007,pp 37508-37514
2009Chitotriosidase and gene therapy for fungal infectionsDjordjevic, Julianne; Sorrell, Tania; Wright, Lesley; Gordon-Thomson, Clare; Holford, P.; Kumari, A.; Moore, G.P.M; Tomkins, L.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteChitotriosidase and gene therapy for fungal infections, CMLS-Cellular and Molecular Life Sciences, vol.66,(6),2009,pp 1116-1125
2003Cloning of CnLYS01, a novel extracellular lysophospholipase of the pathogenic fungus cryptococcus neoformansCoe, John; Latouche, G; Sorrell, Tania; Wilson, Christabel; Wright, Lesley; Infectious Diseases; Central Clinical School: Medicine; Western Clinical School: Westmead Millennium Institute; Infectious Diseases; Western Clinical School: Westmead Millennium InstituteCloning of CnLYS01, a novel extracellular lysophospholipase of the pathogenic fungus cryptococcus neoformans, Gene, vol.316,(1),2003,pp 67-78
2006Correlation of antifungal activity with fungal phospholipase inhibition using a series of bisquaternary ammonium saltsJolliffe, Katrina; Ng, Clarissa; Obando Gutierrez, Daniel; Sorrell, Tania; Widmer, Alfred (Fred); Wright, Lesley; Chemistry; Pharmacy; Chemistry; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteCorrelation of antifungal activity with fungal phospholipase inhibition using a series of bisquaternary ammonium salts, Journal of Medicinal Chemistry, vol.49,(2),2006,pp 811-816
2006Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids.Djordjevic, Julianne; Ganendren, Ranjini; Payne, Jacqueline; Santangelo, Rosemary; Sorrell, Tania; Wright, Lesley; Western Clinical School: Westmead Millennium Institute; Clinical Schools; Medicine; Medicine; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteCryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids., Eukaryotic Cell, vol.6,(1),2006,pp 37-47
2004Cryptococcal Phospholipases: A Novel Lysophospholipase Discovered In The Pathogenic Fungus Cryptococcus Gattii.Chen, Sharon; Payne, Jacqueline; Santangelo, Rosemary; Simpanya, Mukoma; Sorrell, Tania; Widmer, Alfred (Fred); Wright, Lesley; Western Clinical School: Medicine (Westmead); Medicine; Medicine; Infectious Diseases; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteCryptococcal Phospholipases: A Novel Lysophospholipase Discovered In The Pathogenic Fungus Cryptococcus Gattii., Biochemical Journal, vol.384,(2),2004,pp 377-384
2005Detection of antibodies to phospholipase B in patients infected with Cryptococcus neoformans by enzyme-linked immunosorbent assay (ELISA).Chen, Sharon; Santangelo, Rosemary; Sorrell, Tania; Wright, Lesley; Western Clinical School: Medicine (Westmead); Medicine; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteDetection of antibodies to phospholipase B in patients infected with Cryptococcus neoformans by enzyme-linked immunosorbent assay (ELISA)., Medical mycology, vol.43,(4),2005,pp 335-341
2003Detergent-resistant membrane factions contribute to the total 1h nmr-visible lipid signal in cellsDjordjevic, Julianne; Himmelreich, Uwe; Lynch, Garry; Muljadi, N; Schibeci, Stephen; Williamson, Peter; Wright, Lesley; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Medicine; Medicine; Medicine; Concord Clinical School: Age & Alzh Dis Rrch Educ; Western Clinical School: Westmead Millennium InstituteDetergent-resistant membrane factions contribute to the total 1h nmr-visible lipid signal in cells, The FEBS Journal, vol.270,(9),2003,pp 2091-2100
2006Hexadecylphosphocholine (miltefosine) has broad-spectrum fungicidal activity and is efficacious in a mouse model of cryptococcosis.Ganendren, Ranjini; Obando Gutierrez, Daniel; Sorrell, Tania; Widmer, Alfred (Fred); Wright, Lesley; Ellis, David H.; Handke, Rosemary; Clinical Schools; Chemistry; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteHexadecylphosphocholine (miltefosine) has broad-spectrum fungicidal activity and is efficacious in a mouse model of cryptococcosis., Antimicrobial Agents and Chemotherapy, vol.50,(2),2006,pp 414-421
2007In Vitro Activities of Miltefosine and Two Novel Antifungal Biscationic Salts against a Panel of 77 DermatophytesChen, Sharon; Guse, Zofia; Halliday, Catriona; Jolliffe, Katrina; Kong, Fanrong; Lee, Ok; Sorrell, Tania; Widmer, Alfred (Fred); Wright, Lesley; Tong, Zhongsheng; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Molecular & Microbial Bioscien; Chemistry; Western Clinical School: Medicine (Westmead); Infectious Diseases; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteIn Vitro Activities of Miltefosine and Two Novel Antifungal Biscationic Salts against a Panel of 77 Dermatophytes, Antimicrobial Agents and Chemotherapy, vol.51,(6),2007,pp 2219-2222
2007Infrared Spectroscopy of Microorganisms: Characterization, Identification, and DifferentiationAli, Mohamed; Carter, Elizabeth; Ganendren, Ranjini; Lay, Peter; Marshall, Craig; Sorrell, Tania; Wright, Lesley; Chen, C.-I.; Lee, Y.-C.; Chemistry; Chemistry; Clinical Schools; Chemistry; Chemistry; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteInfrared Spectroscopy of Microorganisms: Characterization, Identification, and Differentiation in New Approaches in Biomedical Spectroscopy, American Chemical Society, 2007, pp. 64-84
2003Inhibition of tetraphenylphosphonium-induced nmr-visible lipid accumulation in human breast cells by chlorpromazineDelikatny, Edward; Sathasivam, N; Wright, Lesley; Brammah, Susan; School of Medical Sciences: Pathology; Medicine; Western Clinical School: Westmead Millennium InstituteInhibition of tetraphenylphosphonium-induced nmr-visible lipid accumulation in human breast cells by chlorpromazine, B B A-Molecular and Cell Biology of Lipids, vol.1633,(3),2003,pp 149-160
2006Lipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase.Djordjevic, Julianne; Siafakas, Aritee Rosemary; Sorrell, Tania; Wright, Lesley; Western Clinical School: Westmead Millennium Institute; School of Medical Sciences: Pathology; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteLipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase., Eukaryotic Cell, vol.5,(3),2006,pp 488-498
2002Metabolites released by Cryptococcus neoformans var. neoformans and var. gattii differentially affect human neutrophil functionBubb, William (Bill); Davidson, John; Himmelreich, Uwe; Krockenberger, Mark; Santangelo, Rosemary; Sorrell, Tania; Wright, Lesley; Molecular & Microbial Bioscien; Pharmacy; Western Clinical School: Westmead Millennium Institute; Vet Science Faculty; Medicine; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteMetabolites released by Cryptococcus neoformans var. neoformans and var. gattii differentially affect human neutrophil function, Microbes and Infection, vol.4,(14),2002,pp 1427-1438
2006N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring.Djordjevic, Julianne; Sorrell, Tania; Turner, Kylie; Wright, Lesley; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium InstituteN-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring., B B A - General Subjects, vol.1760,(10),2006,pp 1569-1579
2006Phospholipase B activity enhances adhesion of Cryptococcus neoformans to a human lung epithelial cell lineCarter, Elizabeth; Ganendren, Ranjini; Sorrell, Tania; Widmer, Alfred (Fred); Wright, Lesley; Chemistry; Clinical Schools; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstitutePhospholipase B activity enhances adhesion of Cryptococcus neoformans to a human lung epithelial cell line, Microbes and Infection, vol.8,(4),2006,pp 1006-1015
2004Regulatory Roles For The Homeodomain And C2H2 Zinc Finger Regions Of Cryptococcus Neoformans Ste12Alphap.Sorrell, Tania; Wilson, Christabel; Wright, Lesley; Chang, Yun C.; Kwong-Chung, K. J.; Tscharke, R L; Western Clinical School: Westmead Millennium Institute; Infectious Diseases; Western Clinical School: Westmead Millennium InstituteRegulatory Roles For The Homeodomain And C2H2 Zinc Finger Regions Of Cryptococcus Neoformans Ste12Alphap., Molecular Microbiology, vol.53,(5),2004,pp 1385-96-N/A
2007Role of Conserved Active Site Residues in Catalysis by Phospholipase B1 from Cryptococcus neoformansDjordjevic, Julianne; Sorrell, Tania; Turner, Kylie; Wright, Lesley; George, Anthony M; Jones, Peter M; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium InstituteRole of Conserved Active Site Residues in Catalysis by Phospholipase B1 from Cryptococcus neoformans, Biochemistry, vol.46,(35),2007,pp 10024-10032
2004Role Of Extracellular Phospholipases And Mononuclear Phagocytes In Dissemination Of Cryptococcosis In A Murine ModelDjordjevic, Julianne; Donald, Christine; Santangelo, Rosemary; Sorrell, Tania; Wilson, Christabel; Wright, Lesley; Zoellner, Hans; Yi, Shounan; Western Clinical School: Westmead Millennium Institute; Dentistry Faculty; Medicine; Western Clinical School: Westmead Millennium Institute; Infectious Diseases; Western Clinical School: Westmead Millennium Institute; Dentistry FacultyRole Of Extracellular Phospholipases And Mononuclear Phagocytes In Dissemination Of Cryptococcosis In A Murine Model, Infection and Immunity, vol.72,(4),2004,pp 2229-2239