Browsing by Author Witting, Paul

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Issue DateTitleAuthor(s)Citation
2009Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striationsAntao, Shane; Cullen, Karen; Gervasio, Othon; Goldsbury, Claire; Jeong, Erica; Whiteman, Ineka; Witting, Paul; Bamburg, James R; Guillemin, Gilles; Minamide, Laurie S.; Central Clinical School: Pathology; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Physiology; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: PathologyActivated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations, The Journal of Neuroscience, vol.29, 41,pp 12994-13005
2011The acute-phase protein serum amyloid A induces endothelial dysfunction that is inhibited by high-density lipoproteinAran, Roshanak; Freedman, Saul (Ben); Hua, Susan; Parry, Sarah; Song, Changjie; Witting, Paul; Geczy, Carolyn; Hsu, Kenneth; School of Medical Sciences: Bosch Institute; Concord Clinical School: ANZAC Research Institute; School of Medical Sciences: Bosch Institute; Central Clinical School: Pathology; Concord Clinical School: ANZAC Research Institute; School of Medical Sciences: PathologyThe acute-phase protein serum amyloid A induces endothelial dysfunction that is inhibited by high-density lipoprotein, Free Radical Biology and Medicine, vol.51, 7, 2011,pp 1390-1398
2008Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex IIWitting, Paul; Domann, F; Dong, Lan-Feng; Dyason, J C; Freeman, R; Low, P; Lu, J; Neuzil, Jiri; Prochazka, L; Scheffler, I E; Spitz, D R; Swettenham, Emma; Turanek, J; Valis, k; Wang, Xiu-Fang; Zobalova, Renata; Concord Clinical School: ANZAC Research InstituteAlpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II, Oncogene: including Oncogene Reviews, vol.27,(31),2008,pp 4324-4335
2005Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress.Witting, Paul; Gellert, Nina; Neuzil, Jiri; Procopio, Antonio; Stapelberg, Michael; Swettenham, Emma; Tomasetti, Marco; Concord Clinical School: ANZAC Research InstituteAlpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress., Journal of Biological Chemistry, vol.280,(27),2005,pp 25369-25376
2005Alpha-tocopheryl succinate selectively induces apoptosis in neuroblastoma cells: potential therapy of malignancies of the nervous system?Witting, Paul; Neuzil, Jiri; Salvatore, Brian A.; Swettenham, Emma; Concord Clinical School: ANZAC Research InstituteAlpha-tocopheryl succinate selectively induces apoptosis in neuroblastoma cells: potential therapy of malignancies of the nervous system?, Journal of Neurochemistry, vol.94,(5),2005,pp 1448-1456
2017Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's diseaseCodd, Rachel; Double, Kay; Gotsbacher, Michael; Telfer, Thomas; Witting, Paul; Finkelstein, David; School of Medical Sciences: Pharmacology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PathologyAnalogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease, Metallomics, vol.9, 7, 2017,pp 852-864
2013Beneficial effects of the synthetic antioxidant tert-butyl bisphenol on the hepatic microcirculation in a rat model of diabetes mellitusBenson, Victoria; Le Couteur, David; McMahon, Aisling; Parry, Sarah; Witting, Paul; Physiology; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Central Clinical School: Pathology; School of Medical Sciences: PathologyBeneficial effects of the synthetic antioxidant tert-butyl bisphenol on the hepatic microcirculation in a rat model of diabetes mellitus, Acta Diabetologica, vol.50, 4, 2013,pp 645-649
2010Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptakeGroebler, Ludwig; Issa, Fatiah; Kassiou, Michael; Morrison, Daniel; Rendina, Louis; Rutledge, Peter; Witting, Paul; Bhadbhade, Mohan; School of Medical Sciences: Bosch Institute; Chemistry; Medical Imaging and Radiation Sciences; Chemistry; Chemistry; Chemistry; School of Medical Sciences: PathologyBoronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptake, Journal of Biological Inorganic Chemistry, vol.15, 8,pp 1305-1318
2012Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney diseaseKim, Hyun; Witting, Paul; Abdelkader, Amany; Broughton, Brad; Ding, Alice; Evans, Roger; Kalaignanasundaram, Priyadharshani; Phillips, Jacqueline; Ricardo, Sharon; Wyse, Benjamin; Northern Clinical School: Pathology; School of Medical Sciences: PathologyChronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease, Clinical and Experimental Pharmacology and Physiology, vol.39, 11, 2012,pp 917-929
2003Coenzyme Q10 Supplementation Inhibits Aortic Lipid Oxidation but Fails to Attenuate Intimal Thickening in Balloon-Injured New Zealand White RabbitsStocker, Roland; Witting, Paul; Choy, KATHERINE J.; Deng, Yi-Mo; Hou, J Y; Lau, Antony K.; Wu, Ben J.; School of Medical Sciences: Pathology; Concord Clinical School: ANZAC Research InstituteCoenzyme Q10 Supplementation Inhibits Aortic Lipid Oxidation but Fails to Attenuate Intimal Thickening in Balloon-Injured New Zealand White Rabbits, Free Radical Biology & Medicine, vol.35,(3),2003,pp 300-309
2010Conjugates of Desferrioxamine B (DFOB) with Derivatives of Adamantane or with Orally Available Chelators as Potential Agents for Treating Iron Overload.Codd, Rachel; Groebler, Ludwig; Kalinowski, Danuta; Liu, Joe; Obando Gutierrez, Daniel; Richardson, Desi; Schipanski, Liam; Witting, Paul; School of Medical Sciences: Pharmacology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pharmacology; Chemistry; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PathologyConjugates of Desferrioxamine B (DFOB) with Derivatives of Adamantane or with Orally Available Chelators as Potential Agents for Treating Iron Overload., Journal of Medicinal Chemistry, vol.53, 3,pp 1370-1382
2012Cosupplementation with a synthetic, lipid-soluble polyphenol and vitamin C inhibits oxidative damage and improves vascular function yet does not inhibit acute renal injury in an animal model of rhabdomyolysisGroebler, Ludwig; Hossain, Farjaneh; Kim, Hyun; McMahon, Aisling; Shanu, Anu; Wang, Xiao; Witting, Paul; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Bosch Institute; Northern Clinical School: Pathology; Concord Clinical School: ANZAC Research Institute; Central Clinical School: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PathologyCosupplementation with a synthetic, lipid-soluble polyphenol and vitamin C inhibits oxidative damage and improves vascular function yet does not inhibit acute renal injury in an animal model of rhabdomyolysis, Free Radical Biology and Medicine, vol.52, 9, 2012,pp 1918-1928
2013Cytosolic phospholipase A2alpha sustains pAKT, pERK and AR levels in PTEN-null/mutated prostate cancer cellsAssinder, Stephen; Dong, Qihan; Gong, Zhen; Hua, Sheng; Niknami, Marzieh; Richardson, Desi (Des); Teng, Ying; Vignarajan, Soma; Witting, Paul; Yao, Mu; Hejazi, Leila; School of Medical Sciences: Physiology; Central Clinical School: Medicine; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Bosch Institute; Central Clinical School: Medicine; School of Medical Sciences: Pathology; Anaesthesia; Central Clinical School: Medicine; School of Medical Sciences: Pathology; Central Clinical School: MedicineCytosolic phospholipase A2alpha sustains pAKT, pERK and AR levels in PTEN-null/mutated prostate cancer cells, Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol.1831, 6, 2013,pp 1146-1157
2010Decrease in expression or activity of cytosolic phospholipase A(2)alpha increases cyclooxygenase-1 action: A cross-talk between key enzymes in arachidonic acid pathway in prostate cancer cells.Dong, Qihan; Niknami, Marzieh; Patel, Manish; Sved, Paul; Witting, Paul; Yao, Mu; Hua, Sheng; Kita, Yoshihiro; Shimizu, Takao; Vignarajan, Soma; Central Clinical School: Medicine; Central Clinical School: Medicine; Western Clinical School: Surgery; Central Clinical School: Medicine; School of Medical Sciences: Pathology; Central Clinical School: MedicineDecrease in expression or activity of cytosolic phospholipase A(2)alpha increases cyclooxygenase-1 action: A cross-talk between key enzymes in arachidonic acid pathway in prostate cancer cells., Biochimica et Biophysica Acta-Molecular Basis of Disease, vol.1801, 7,pp 731-7
2015Effects of 8 weeks of CPAP on lipid-based oxidative markers in obstructive sleep apnea: a randomized trialGrunstein, Ron (Ronald); Hoyos, Camilla; Maw, Aung Min; Phillips, Craig; Sivam, Sheila; Witting, Paul; Yee, Brendon; Central Clinical School: Woolcock Inst. of Medical Research; Central Clinical School: Woolcock Inst. of Medical Research; Sydney Talent; Northern Clinical School: Medicine; Central Clinical School: Medicine; School of Medical Sciences: Pathology; Central Clinical School: Woolcock Inst. of Medical ResearchEffects of 8 weeks of CPAP on lipid-based oxidative markers in obstructive sleep apnea: a randomized trial, Journal of Sleep Research, vol.24, 3, 2015,pp 339-345
2009Effects of hydrogen peroxide and apolipoprotein e isoforms on apolipoprotein e trafficking in HepG2 cellsHarris, Matthew; Kritharides, Leonard; Le Couteur, David; Sabaretnam, Tharani; Witting, Paul; Kockx, Maaike; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; School of Medical Sciences: PathologyEffects of hydrogen peroxide and apolipoprotein e isoforms on apolipoprotein e trafficking in HepG2 cells, Clinical and Experimental Pharmacology & Physiology, vol.36, 12,pp e96-e102
2009Endogenous adenosine selectively modulates oxidant stress via the A1 receptor in ischemic heartsShanu, Anu; Witting, Paul; Blackburn, Michael; Ellis, Natasha A.; Headrick, John; Reichelt, Melissa; Willems, Laura; Central Clinical School: Pathology; School of Medical Sciences: PathologyEndogenous adenosine selectively modulates oxidant stress via the A1 receptor in ischemic hearts, Antioxidants and Redox Signaling, vol.11, 11,pp 2641-2650
2006The Endothelium-Derived Hyperpolarizing Factor, H-2O-2, Promotes Metal-Ion Efflux in Aortic Endothelial Cells: Elemental Mapping by a Hard X-ray MicroprobeAitken, Jade; Dillon, Carolyn; Harris, Hugh; Lay, Peter; Rayner, Benjamin; Witting, Paul; Cai, Zhonghou; Lai, Barry; Stocker, Roland; Chemistry; Chemistry; Chemistry; Chemistry; Concord Clinical School: ANZAC Research Institute; School of Medical Sciences: PathologyThe Endothelium-Derived Hyperpolarizing Factor, H-2O-2, Promotes Metal-Ion Efflux in Aortic Endothelial Cells: Elemental Mapping by a Hard X-ray Microprobe, Biochemistry, vol.45,(41),2006,pp 12500-12509
2018Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer's diseaseChami, Belal; Lim, Julia; Middleton, Terence; Sutherland, Greg; Witting, Paul; Youssef, Priscilla; Westmead Clinical School: Surgery; School of Medical Sciences: Pathology; School of Medical Sciences: Physiology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyEvidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer's disease, Scientific Reports, vol.8, 1, 2018,pp 11553-N/A
2018Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer's diseaseChami, Belal; Lim, Julia; Middleton, Terence; Sutherland, Greg; Witting, Paul; Youssef, Priscilla; Westmead Clinical School: Surgery; School of Medical Sciences: Pathology; School of Medical Sciences: Physiology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyEvidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer's disease, Scientific Reports, vol.8, 1, 2018,pp 11553-N/A