Browsing by Author Wilmott, James

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Issue DateTitleAuthor(s)Citation
2009Atypical Spitzoid Melanocytic Tumors With Positive Sentinel Lymph Nodes in Children and Teenagers, and Comparison With Histologically Unambiguous and Lethal Melanomas.McCarthy, Stanley; Murali, Rajmohan; Scolyer, Richard; Shaw, Helen; Thompson, John; Brady, Mary; Busam, Klaus; Coit, Daniel G.; Dusza, Stephen; Kayton, Marc; LaQuaglia, Michael; Pulitzer, Melissa; Wilmott, James; Central Clinical School: Inst. of Anatomical Pathology RPAH; Central Clinical School: Pathology; Central Clinical School: Pathology; Central Clinical School: Sydney Melanoma Unit; Central Clinical School: SurgeryAtypical Spitzoid Melanocytic Tumors With Positive Sentinel Lymph Nodes in Children and Teenagers, and Comparison With Histologically Unambiguous and Lethal Melanomas., American Journal of Surgical Pathology, vol.33, 9,pp 1386-1395
2013BRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III MelanomaCampain, Anna; Carter, Candace; De Silva, Chitra; Gerega, Sebastien; Hersey, Peter; Kefford, Richard (Rick); Lai, Kenneth; Mann, Graham; Pianova, Svetlana; Pupo, Gulietta; Schramm, Sarah-Jane; Scolyer, Richard; Synnott, Catherine; Thompson, John; Wilmott, James; Yang, Yee (Jean); Mathematics & Statistics; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Melanoma Foundation; Biological Sciences; Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Clinical Ophthal & Eye Health; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Central Clinical School: Pathology; RADS - Research Analytics & Data Strategy; Central Clinical School: Surgery; Central Clinical School: Surgery; Mathematics & StatisticsBRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III Melanoma, The Journal of Investigative Dermatology, vol.133, 2, 2013,pp 509-517
2016BRAF(V600E) and NRAS(Q61L/Q61R) mutation analysis in metastatic melanoma using immunohistochemistry: a study of 754 cases highlighting potential pitfalls and guidelines for interpretation and reportingCooper, Wendy Anne; Kakavand, Hojabr; Long, Georgina; O'Toole, Sandra; Saw, Robyn; Scolyer, Richard; Smith, Elisabeth; Walker, Emily; Wilmott, James; Yu, Bing; Lum, Trina; Selinger, Christina; Central Clinical School: Medicine; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Medicine; Medicine; Central Clinical School: Surgery; Central Clinical School: MedicineBRAF(V600E) and NRAS(Q61L/Q61R) mutation analysis in metastatic melanoma using immunohistochemistry: a study of 754 cases highlighting potential pitfalls and guidelines for interpretation and reporting, Histopathology, vol.69, 4, 2016,pp 680-686
2013BRAF(V600E) protein expression and outcome from BRAF inhibitor treatment in BRAF(V600E) metastatic melanomaHaydu, Lauren; Kefford, Richard (Rick); Long, Georgina; Menzies, Alexander; Scolyer, Richard; Thompson, John; Wilmott, James; Capper, D; Preusser, Matthias; von Diemling, Andreas Von; Zhang, Yuxiao; Central Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryBRAF(V600E) protein expression and outcome from BRAF inhibitor treatment in BRAF(V600E) metastatic melanoma, British Journal of Cancer, vol.108, 4, 2013,pp 924-931
2018CD103+ Tumor-Resident CD8+ T Cells Are Associated with Improved Survival in Immunotherapy-Naive Melanoma Patients and Expand Significantly During Anti-PD-1 TreatmentBritton, Warwick; Chen, Jinbiao; Edwards, Jarem; Ferguson, Angela; Gide, Tuba; Hersey, Peter; Hewavisenti, Rehana; Long, Georgina; Madore, Jason; Menzies, Alexander Maxwel; Palendira, Umaimainthan; Quek, Camelia; Saw, Robyn; Scolyer, Richard; Tasker, Annie; Thompson, John; Weninger, Wolfgang; Wilmott, James; Gebhardt, Thomas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Medicine; Physiology; Northern Clinical School: Surgery; Veterinary Science; Northern Clinical School: Medicine; Central Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Pathology; Charles Perkins Centre; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryCD103+ Tumor-Resident CD8+ T Cells Are Associated with Improved Survival in Immunotherapy-Naive Melanoma Patients and Expand Significantly During Anti-PD-1 Treatment, Clinical Cancer Research, vol.24, 13, 2018,pp 3036-3045
2015Clinicopathologic features associated with efficacy and long-term survival in metastatic melanoma patients treated with BRAF or combined BRAF and MEK inhibitorsCarlino, Matteo; Drummond, Martin John; Guminski, Alexander; Kefford, Richard (Rick); Lo, Serigne; Long, Georgina; Lyle, Megan; Menzies, Alexander Maxwel; Scolyer, Richard; Thompson, John; Wilmott, James; Chan, Matthew M K; Western Clinical School: Medicine (Westmead); School of Public Health: Public Health; Medicine Faculty Office; Western Clinical School: Westmead Institute for Medical Res; The George Institute for Global Health; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryClinicopathologic features associated with efficacy and long-term survival in metastatic melanoma patients treated with BRAF or combined BRAF and MEK inhibitors, Cancer, vol.121, 21, 2015,pp 3826-3835
2015Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signalingDe Paoli-Iseppi, Ricardo; Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Strbenac, Dario; Tiffen, Jessamy; Wilmott, James; Yang, Jean Yee Hwa; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Mathematics & Statistics; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Mathematics & StatisticsCombining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling, Oncotarget, vol.6, 25, 2015,pp 21507-21521
2016Comparison of whole-exome sequencing of matched fresh and formalin fixed paraffin embedded melanoma tumours: implications for clinical decision makingKakavand, Hojabr; Long, Georgina; Mann, Graham; Menzies, Alexander Maxwel; Pupo, Gulietta; Scolyer, Richard; Wilmott, James; De Paoli-Iseppi, Ricardo; Dias, Kerith-Rae; Dinger, Marcel; Hayward, Nicholas K; Johansson, Peter; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Central Clinical School: Pathology; Central Clinical School: SurgeryComparison of whole-exome sequencing of matched fresh and formalin fixed paraffin embedded melanoma tumours: implications for clinical decision making, Pathology, vol.48, 3, 2016,pp 261-266
2014Concordant BRAFV600E mutation status in primary melanomas and associated naevi: implications for mutation testing of primary melanomasKakavand, Hojabr; Kefford, Richard (Rick); Long, Georgina; O'Toole, Sandra; Scolyer, Richard; Thompson, John; Wilmott, James; Crainic, Oana; Lum, Trina; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Pathology; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryConcordant BRAFV600E mutation status in primary melanomas and associated naevi: implications for mutation testing of primary melanomas, Pathology, vol.46, 3, 2014,pp 193-198
2015Detailed Pathological Examination of Completion Node Dissection Specimens and Outcome in Melanoma Patients with Minimal (<01 mm) Sentinel Lymph Node MetastasesMadore, Jason; Nieweg, Omgo; Scolyer, Richard; Thompson, John; Vilain, Ricardo; Wang, Shu; Wilmott, James; Holtkamp, Lodewijka H J; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Medicine; Central Clinical School: SurgeryDetailed Pathological Examination of Completion Node Dissection Specimens and Outcome in Melanoma Patients with Minimal (<01 mm) Sentinel Lymph Node Metastases, Annals of Surgical Oncology, vol.22, 9, 2015,pp 2972-2977
2014DNA methylation and gene deletion analysis of brain metastases in melanoma patients identifies mutually exclusive molecular alterationsBuckland, Michael; Scolyer, Richard; Thompson, John; Wilmott, James; Barkhoudarian, Garni; Hoon, D; Huynh, Janie L; Kelly, Daniel F; Marzese, Diego M; Morton, Donald L.; Murali, Rajmohan; Roqué, Maria; Vargas-Roig, Laura M; School of Medical Sciences: Brain & Mind Research Institute; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryDNA methylation and gene deletion analysis of brain metastases in melanoma patients identifies mutually exclusive molecular alterations, Neuro-Oncology, vol.16, 11, 2014,pp 1499-1509
2017Dynamic changes in PD-L1 expression and immune infiltrates early during treatment predict response to PD-1 blockade in MelanomaCarlino, Matteo; Guminski, Alexander; Jakrot, Valerie; Kakavand, Hojabr; Kefford, Richard (Rick); Liniker, Elizabeth; Lo, Serigne; Long, Georgina; Madore, Jason; Menzies, Alexander Maxwel; Saw, Robyn; Scolyer, Richard; Thompson, John; Vilain, Ricardo; Wilmott, James; Cooper, Adam J.; Howle, Julie; Kong, Benjamin; Westmead Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Westmead Clinical School: Medicine; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: SurgeryDynamic changes in PD-L1 expression and immune infiltrates early during treatment predict response to PD-1 blockade in Melanoma, Clinical Cancer Research, vol.23, 17, 2017,pp 5024-5033
2014Dynamics of chemokine, cytokine, and growth factor serum levels in BRAF-mutant melanoma patients during BRAF inhibitor treatmentHaydu, Lauren; Hersey, Peter; Kefford, Richard (Rick); Long, Georgina; Menzies, Alexander Maxwel; Scolyer, Richard; Thompson, John; Wilmott, James; Hyman, Jessica; Lum, Trina; Central Clinical School: Surgery; Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryDynamics of chemokine, cytokine, and growth factor serum levels in BRAF-mutant melanoma patients during BRAF inhibitor treatment, The Journal of Immunology, vol.192, 5, 2014,pp 2505-2513
2013Effects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment and on progressionHaydu, Lauren; Howle, Julie; Kefford, Richard (Rick); Long, Georgina; Rizos, Helen; Scolyer, Richard; Sharma, Raghwa; Tembe, Varsha; Thompson, John; Wilmott, James; Central Clinical School: Surgery; Western Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Pathology; Western Clinical School: Pathology; Western Clinical School: Medicine (Westmead); Central Clinical School: Surgery; Central Clinical School: SurgeryEffects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment and on progression, Pigment Cell and Melanoma Research, vol.26, 4, 2013,pp 499-508
2011The emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancersHersey, Peter; Scolyer, Richard; Wilmott, James; Zhang, Xu Dong; Medicine Faculty Office; Central Clinical School: Pathology; School of Medical Sciences: PathologyThe emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancers, Pathology, vol.43, 6, 2011,pp 657-671
2015Endosialin Expression in Metastatic Melanoma Tumor Microenvironment Vasculature: Potential Therapeutic ImplicationsScolyer, Richard; Wilmott, James; Donovan, Nicholas C; Hoon, D; Huang, Sharon K; Jones, Peter; Kiyohara, Eiji; O’Shannessy, Daniel; Somers, Elizabeth; Takeshima, L; Central Clinical School: Pathology; Central Clinical School: SurgeryEndosialin Expression in Metastatic Melanoma Tumor Microenvironment Vasculature: Potential Therapeutic Implications, Cancer Microenvironment, vol.8, 2, 2015,pp 111-118
2015Expression of the class 1 histone deacetylases HDAC8 and 3 are associated with improved survival of patients with metastatic melanomaCarlino, Matteo; Colebatch, Andrew; Hersey, Peter; Kakavand, Hojabr; Long, Georgina; Scolyer, Richard; Thompson, John; Wilmott, James; Shang, Ping; Western Clinical School: Medicine (Westmead); Medicine; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryExpression of the class 1 histone deacetylases HDAC8 and 3 are associated with improved survival of patients with metastatic melanoma, Modern Pathology, vol.28, 7, 2015,pp 884-894
2018HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanomaBeaumont, Kimberley; Ferguson, Peter; Gallagher, Stuart; Gunatilake, Dilini; Haass, Nikolas; Heinemann, Anja; Hersey, Peter; Madore, Jason; Rizos, Helen; Sharp, Danae; Tiffen, Jessamy; Weninger, Wolfgang; Wilmott, James; Central Clinical School: Centenary Institute; Medicine; Westmead Clinical School: Medicine; Northern Clinical School: Kolling Institute; Central Clinical School: Centenary Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryHDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma, International Journal of Cancer, vol.142, 9, 2018,pp 1926-1937
2013Immunohistochemistry Is Highly Sensitive and Specific for the Detection of V600E BRAF Mutation in MelanomaKefford, Richard (Rick); Long, Georgina; Scolyer, Richard; Thompson, John; Wilmott, James; Capper, D; Preusser, Matthias; von Deimling, Andreas; Zhang, Yuxiao; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryImmunohistochemistry Is Highly Sensitive and Specific for the Detection of V600E BRAF Mutation in Melanoma, The American Journal of Surgical Pathology, vol.37, 1, 2013,pp 61-65
2015INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomasScolyer, Richard; Wilmott, James; Chi, Meng Na; Croft, Amanda; et al, Various; Guo, Sutang; Guo, X Y; Jin, Lei; Liu, Tao; Liu, Xiao Ying; Tseng, Hsin-Yi; Wang, ChunYan; Yan, Xu Guang; Central Clinical School: Pathology; Central Clinical School: SurgeryINPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas, Oncotarget, vol.6, 37, 2015,pp 39891-39907