Browsing by Author Wienert, Beeke

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Issue DateTitleAuthor(s)Citation
2015Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globinLester, Krystal; Matthews, Jacqueline; Wilkinson-White, Lorna; Crossley, Merlin Paul; Funnell, Alister; Norton, Laura; Pearson, Richard; Porteus, Matthew; Quinlan, Kate; Vadolas, Jim; Wienert, Beeke; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceEditing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin, Nature Communications, vol.6, 7085, 2015,pp 1-8
2015Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity.Cordwell, Stuart; Crossley, Paul (Merlin); Kwok, Alister; Lee, Ming Min; Lee, Stella Hoi Yi; Nicholas, Hannah; Tan, Yee Mun; Dewi, Vitri; Funnell, Alister; Isono, Kyo-ichi; Knights, Alexander; Mak, Ka Sin; Pearson, Richard; Quinlan, Kate; Wienert, Beeke; Molecular Bioscience; Molecular Bioscience; Molecular Bioscience; School of Medical Sciences: Biomedical Sciences; Molecular Bioscience; Molecular Bioscience; Western Clinical School: Medicine (Westmead)Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity., The Journal of Biological Chemistry, vol.290, 13, 2015,pp 8591-8605
2014Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factorTan, Lit-Yeen; Artuz, Crisbel; Burdach, Jon; Crossley, Merlin Paul; Funnell, Alister; Lim, Wooi; Mak, Ka Sin; Pearson, Richard; Wienert, Beeke; Molecular BioscienceRegions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor, Nucleic Acids Research, vol.42, 1, 2014,pp 276-289
2011Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1Dastmalchi, Siavoush; Gamsjaeger, Roland; Mackay, Joel; Matthews, Jacqueline; Stokes, Philippa; Wienert, Beeke; Wilkinson-White, Lorna; Crossley, Merlin; Molecular Bioscience; Molecular Bioscience; Molecular Bioscience; Molecular Bioscience; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceStructural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1, Proceedings of the National Academy of Sciences, vol.108, 35, 2011,pp 14443-14448