Browsing by Author Whitelock, John M.

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Issue DateTitleAuthor(s)Citation
2016Ablation of Perlecan domain I heparan sulfate reduces progressive cartilage degradation, synovitis, and osteophyte size in post-traumatic osteoarthritisJackson, Miriam; Little, Christopher; Melrose, James; Shu, Cindy; Smith, Margaret; Smith, Susan; Lord, Megan; Penm, Steven; Whitelock, John M.; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint ResearchAblation of Perlecan domain I heparan sulfate reduces progressive cartilage degradation, synovitis, and osteophyte size in post-traumatic osteoarthritis, Arthritis & Rheumatology, vol.68, 4, 2016,pp 868-879
2016Bioengineered human heparin with anticoagulant activityLyons, Guy; Cheng, Bill; Lord, Megan; Rnjak-Kovacina, Jelena; Tang, Fengying; Whitelock, John M.; Central Clinical School: MedicineBioengineered human heparin with anticoagulant activity, Metabolic Engineering, vol.38, N/A, 2016,pp 105-114
2008Characterization and purification of glycosaminoglycans from crude biological samplesRoubin, Rebecca; Davies, N. P.; Whitelock, John M.; PharmacyCharacterization and purification of glycosaminoglycans from crude biological samples, Journal of Agricultural and Food Chemistry, vol.56,(2),2008,pp 343-348
2011Colocalization in vivo and association in vitro of perlecan and elastinMelrose, James; Smith, Margaret; Smith, Susan; Weiss, Anthony; Hayes, Anthony; Lord, Megan; Whitelock, John M.; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Molecular BioscienceColocalization in vivo and association in vitro of perlecan and elastin, Histochemistry and Cell Biology, vol.136, N/A, 2011,pp 437-454
2008Diverse Cell Signaling Events Modulated by PerlecanMelrose, James; Iozzo, Renato V; Whitelock, John M.; Northern Clinical School: SurgeryDiverse Cell Signaling Events Modulated by Perlecan, Biochemistry, vol.47, 43, 2008,pp 11174-11183
2010Heparan Sulfate-Dependent Signaling of Fibroblast Growth Factor 18 by Chondrocyte-Derived Perlecan.Melrose, James; Chuang, Christine; Freeman, Craig; Iozzo, Renato V; Knox, Sarah; Lord, Megan; Rees, Martin D; Whitelock, John M.; Northern Clinical School: SurgeryHeparan Sulfate-Dependent Signaling of Fibroblast Growth Factor 18 by Chondrocyte-Derived Perlecan., Biochemistry, vol.49, 26,pp 5524-5532
2009Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxidesDavies, Michael; Bottle, Steven; Fairfull-Smith, Kathryn; Malle, Ernst; Rees, Martin D; Whitelock, John M.; Central Clinical School: Heart Research InstituteInhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides, Biochemical Journal, vol.421, 1, 2009,pp 79-86
2013Mast Cells Produce Novel Shorter Forms of Perlecan That Contain Functional Endorepellin: A Role in Angiogenesis and Wound HealingAlkhouri, Hatem; Hughes, J. Margaret; Lyons, James (Guy); Cheng, Bill; Iozzo, Renato V; Jung, MoonSun; Lord, Megan; McCarthy, Simon J; Whitelock, John M.; Pharmacy; Pharmacy; Central Clinical School: MedicineMast Cells Produce Novel Shorter Forms of Perlecan That Contain Functional Endorepellin: A Role in Angiogenesis and Wound Healing, Journal of Biological Chemistry, vol.288, 5, 2013,pp 3289-3304
2018The multifaceted roles of perlecan in fibrosisMelrose, James; Lord, Megan; Rnjak-Kovacina, Jelena; Smith, James; Tang, Fengying; Whitelock, John M.; Northern Clinical School: SurgeryThe multifaceted roles of perlecan in fibrosis, Matrix Biology, vol.68-69, N/A, 2018,pp 150-166
2018The multifaceted roles of perlecan in fibrosisMelrose, James; Lord, Megan; Rnjak-Kovacina, Jelena; Smith, James; Tang, Fengying; Whitelock, John M.; Northern Clinical School: SurgeryThe multifaceted roles of perlecan in fibrosis, Matrix Biology, vol.68-69, N/A, 2018,pp 150-166
2018The multifaceted roles of perlecan in fibrosisMelrose, James; Lord, Megan; Rnjak-Kovacina, Jelena; Smith, James; Tang, Fengying; Whitelock, John M.; Northern Clinical School: SurgeryThe multifaceted roles of perlecan in fibrosis, Matrix Biology, vol.68-69, N/A, 2018,pp 150-166
2018The multifaceted roles of perlecan in fibrosisMelrose, James; Lord, Megan; Rnjak-Kovacina, Jelena; Smith, James; Tang, Fengying; Whitelock, John M.; Northern Clinical School: SurgeryThe multifaceted roles of perlecan in fibrosis, Matrix Biology, vol.68-69, N/A, 2018,pp 150-166
2018The multifaceted roles of perlecan in fibrosisMelrose, James; Lord, Megan; Rnjak-Kovacina, Jelena; Smith, James; Tang, Fengying; Whitelock, John M.; Northern Clinical School: SurgeryThe multifaceted roles of perlecan in fibrosis, Matrix Biology, vol.68-69, N/A, 2018,pp 150-166
2018The multifaceted roles of perlecan in fibrosisMelrose, James; Lord, Megan; Rnjak-Kovacina, Jelena; Smith, James; Tang, Fengying; Whitelock, John M.; Northern Clinical School: SurgeryThe multifaceted roles of perlecan in fibrosis, Matrix Biology, vol.68-69, N/A, 2018,pp 150-166
2010Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecanDavies, Michael; Chuang, Christine; Iozzo, Renato V; Malle, Ernst; Nilasaroya, Anastasia; Rees, Martin D; Whitelock, John M.; Central Clinical School: Heart Research InstituteMyeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan, Matrix biology: journal of the International Society for Matrix Biology, vol.29, 1,pp 63-73
2017Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degenerationHunyor, Alex; Krilis, Matthew; Madigan, Michele; McCluskey, Peter; Abdelatti, Mahmoud; Giannakopoulos, Bill; Guymer, Robyn; Krilis, Steven; Qi, Jian Cheng; Qi, Miao; Whitelock, John M.; Wong, Jason W H; Zhang, Peng; Save Sight Institute; Central Clinical School: Medicine; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Clinical Ophthal & Eye HealthNitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration, Oncotarget, vol.8, 30, 2017,pp 49016-49032
2014Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cellsChuang, Christine; Davies, Michael; Degendorfer, Georg; Hammer, Astrid; Malle, Ernst; Whitelock, John M.; Central Clinical School: Heart Research Institute; Central Clinical School: Heart Research Institute; Central Clinical School: Heart Research InstituteOxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells, The Biochemical Journal, vol.459, 2, 2014,pp 313-322
2008Oxidative damage to extracellular matrix and its role in human pathologiesDavies, Michael; Kennett, Eleanor C; Rees, Martin D; Whitelock, John M.; Central Clinical School: Heart Research InstituteOxidative damage to extracellular matrix and its role in human pathologies, Free Radical Biology and Medicine, vol.44, 12, 2008,pp 1973-2001
2016Pericellular colocalisation and interactive properties of type VI collagen and perlecan in the intervertebral discLittle, Christopher; Melrose, James; Hayes, Anthony; Lord, Megan; Shu, Cindy; Whitelock, John M.; Northern Clinical School: Kolling Institute; Northern Clinical School: SurgeryPericellular colocalisation and interactive properties of type VI collagen and perlecan in the intervertebral disc, European Cells and Materials, vol.32, N/A, 2016,pp 40-57
2010Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chainsDavies, Michael; Hammer, Astrid; Kennett, Eleanor C; Malle, Ernst; Rees, Martin D; Whitelock, John M.; Central Clinical School: Heart Research InstitutePeroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains, Free Radical Biology & Medicine, vol.49, 2,pp 282-293