Browsing by Author West, Nicholas

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Issue DateTitleAuthor(s)Citation
2010Cutinase-like protein-6 of Mycobacterium tuberculosis is recognised in tuberculosis patients and protects mice against pulmonary infection as a single and fusion protein vaccineBritton, Warwick; Pinto, Rachael; Triccas, James; Shanahan, Erin; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: MedicineCutinase-like protein-6 of Mycobacterium tuberculosis is recognised in tuberculosis patients and protects mice against pulmonary infection as a single and fusion protein vaccine, Vaccine, vol.28, 5,pp 1341-1346
2009Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identificationBritton, Warwick; West, Nicholas; Chen, Jian-Feng; Chow, Francess M E; Randall, Elizabeth J; Ribeiro, Jose M C; Wu, Jing; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteCutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification, The FASEB Journal, vol.23,(doi: 10.1096/fj.08-114421),2009,pp N/A-N/A
2011Delivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosisBritton, Warwick; Triccas, James; West, Nicholas; Medveczky, C Jill; Ramshaw, Ian; Thomson, Scott A; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary InstituteDelivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosis, Vaccine, vol.29, 44, 2011,pp 7759-7765
2012Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration StrategyBritton, Warwick; Payne, Richard; Tran, Anh; West, Nicholas; Central Clinical School: Centenary Institute; Chemistry; Chemistry; Central Clinical School: Centenary InstituteElucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration Strategy, ChemMedChem: chemistry enabling drug discovery, vol.7, 6, 2012,pp 1031-1043
2013Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosisBritton, Warwick; Triccas, James; West, Nicholas; Leotta, Lisa; Leyh, Thomas; Pinto, Rachel; Shanahan, Erin; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary InstituteHost cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosis, The Journal of Infectious Diseases, vol.207, 5, 2013,pp 778-785
2008Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosisBritton, Warwick; West, Nicholas; Wozniak, Teresa; Feng, Carl G; Ribeiro, Jose M C; Sher, Alan; Valenzuela, Jesus; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: OfficeImmunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosis, Vaccine, vol.26, 31, 2008,pp 3853-3859
2013Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU)Britton, Warwick; Payne, Richard; Tran, Anh; West, Nicholas; Baker, Edward; Wen, Daying; Central Clinical School: Centenary Institute; Chemistry; Chemistry; Central Clinical School: Centenary InstituteInhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU), Organic and Biomolecular Chemistry, vol.11, 46, 2013,pp 8113-8126
2011Inhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leadsBritton, Warwick; Cergol, Katie; Payne, Richard; West, Nicholas; Xue, Millie; Randall, Elizabeth J; Central Clinical School: Centenary Institute; Chemistry; Chemistry; Central Clinical School: Centenary Institute; ChemistryInhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leads, Chemical Communications, vol.47, 18, 2011,pp 5166-5168
2014Nitrate supplementation and high-intensity performance in competitive cyclistsHoon, Matthew Wallace; Johnson, Nathan; Burke, Louise; Halson, Shona; Hopkins, William; Jones, Andrew; Martin, David; West, Nicholas; Exercise Health and Performance; Exercise Health and PerformanceNitrate supplementation and high-intensity performance in competitive cyclists, Applied Physiology, Nutrition and Metabolism, vol.39, 9, 2014,pp 1043-1049
2014Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killingMonteleone, Mercedes; West, Nicholas; Donald, Cortny; Ly, Diane; Maddocks, Tracey; McArthur, Jason D.; Nizet, Victor; Ranson, Marie; Sanderson-Smith, Martina L.; Skora, Amanda; Taylor, Jude; Tsatsaronis, James; Walker, Mark James; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstitutePlasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing, Journal of Innate Immunity, vol.6, 2, 2014,pp 240-250
2018PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infectionAshhurst (was Tyne), Anneliese; Britton, Warwick; Chan, Hak-Kim (Kim); Chan, John Gar Yan; Florido, Manuela; Lin, Leon; Parumasivam, Thaigarajan; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: Pathology; Central Clinical School: Centenary Institute; PharmacyPLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection, PloS One, vol.13, 3, 2018,pp N/A-N/A
2018PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infectionAshhurst (was Tyne), Anneliese; Britton, Warwick; Chan, Hak-Kim (Kim); Chan, John Gar Yan; Florido, Manuela; Lin, Leon; Parumasivam, Thaigarajan; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: Pathology; Central Clinical School: Centenary Institute; PharmacyPLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection, PloS One, vol.13, 3, 2018,pp N/A-N/A
2018PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infectionAshhurst (was Tyne), Anneliese; Britton, Warwick; Chan, Hak-Kim (Kim); Chan, John Gar Yan; Florido, Manuela; Lin, Leon; Parumasivam, Thaigarajan; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: Pathology; Central Clinical School: Centenary Institute; PharmacyPLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection, PloS One, vol.13, 3, 2018,pp N/A-N/A
2018PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infectionAshhurst (was Tyne), Anneliese; Britton, Warwick; Chan, Hak-Kim (Kim); Chan, John Gar Yan; Florido, Manuela; Lin, Leon; Parumasivam, Thaigarajan; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: Pathology; Central Clinical School: Centenary Institute; PharmacyPLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection, PloS One, vol.13, 3, 2018,pp N/A-N/A
2018PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infectionAshhurst (was Tyne), Anneliese; Britton, Warwick; Chan, Hak-Kim (Kim); Chan, John Gar Yan; Florido, Manuela; Lin, Leon; Parumasivam, Thaigarajan; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: Pathology; Central Clinical School: Centenary Institute; PharmacyPLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection, PloS One, vol.13, 3, 2018,pp N/A-N/A
2018PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infectionAshhurst (was Tyne), Anneliese; Britton, Warwick; Chan, Hak-Kim (Kim); Chan, John Gar Yan; Florido, Manuela; Lin, Leon; Parumasivam, Thaigarajan; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: Pathology; Central Clinical School: Centenary Institute; PharmacyPLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection, PloS One, vol.13, 3, 2018,pp N/A-N/A
2018PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infectionAshhurst (was Tyne), Anneliese; Britton, Warwick; Chan, Hak-Kim (Kim); Chan, John Gar Yan; Florido, Manuela; Lin, Leon; Parumasivam, Thaigarajan; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: Pathology; Central Clinical School: Centenary Institute; PharmacyPLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection, PloS One, vol.13, 3, 2018,pp N/A-N/A
2018PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infectionAshhurst (was Tyne), Anneliese; Britton, Warwick; Chan, Hak-Kim (Kim); Chan, John Gar Yan; Florido, Manuela; Lin, Leon; Parumasivam, Thaigarajan; West, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: Pathology; Central Clinical School: Centenary Institute; PharmacyPLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection, PloS One, vol.13, 3, 2018,pp N/A-N/A
2014Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individualsGebski, Val; Cripps, Allan; Fricker, Peter; Horn, Peggy L; Lahtinen, Sampo J; Pyne, David; West, Nicholas; School of Public Health: NH&MRC Clinical Trials CentreProbiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individuals, Clinical Nutrition, vol.33, 4, 2014,pp 581-587
2017Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesisBritton, Warwick; Conroy, Trent; Dowman, Luke J.; Giltrap, Andrew Michael; Pang, Angel; Payne, Richard; Tran, Anh Thu Eve; Watson, Emma; Bugg, Timothy D.H.; Charman, Susan; Crick, Dean; Dowson, Christopher; Linington, Roger G.; Mahapatra, Sebabrata; Pujari, Venugopal; Roper, David; Saunders, Jessica; Tod, Julie; West, Nicholas; Wong, Weng Ruh; Central Clinical School: Centenary Institute; Chemistry; Chemistry; Chemistry; Central Clinical School: Centenary Institute; Chemistry; Chemistry; ChemistrySansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis, Nature Communications, vol.8, N/A, 2017,pp 1-9