Browsing by Author Tomlinson, Christopher

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Issue DateTitleAuthor(s)Citation
2016The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNABryan, Tracy; Mathias, Jordan; Tomlinson, Christopher; Holien, Jessica; Parker, Michael; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA, Biochimie, vol.128-129, N/A, 2016,pp 114-121
2015A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of TelomeraseBryan, Tracy; Killedar, Anagha; Pickett, Hilda; Reddel, Roger; Sobinoff, Alexander; Stutz, Michael D.; Tomlinson, Christopher; Beesley, Jonathan; Chenevix-Trench, Georgia; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Medicine; Central Clinical School: Medicine; Children's Hospital Westmead: Childrens Medical Research InsA Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase, PLoS Genetics, vol.11, 6, 2015,pp 1-23
2014Inhibition of Telomerase: Promise, Progress and Potential PitfallsBryan, Tracy; Cohen, Scott; Tomlinson, Christopher; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)Inhibition of Telomerase: Promise, Progress and Potential Pitfalls in Cancer Drug Design and Discovery, Academic Press, 2014, pp. 491-527
2017Quantitative assays for measuring human telomerase activity and DNA binding propertiesBryan, Tracy; Cohen, Scott; Jurczyluk, Julie; Sasaki, Natsuki; Tomlinson, Christopher; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Ins; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)Quantitative assays for measuring human telomerase activity and DNA binding properties, Methods, vol.114, N/A, 2017,pp 85-95
2015Two-step mechanism involving active-site conformational changes regulates human telomerase DNA bindingBryan, Tracy; Cohen, Scott; Moye, Aaron; Tomlinson, Christopher; Holien, Jessica; Parker, Michael; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsTwo-step mechanism involving active-site conformational changes regulates human telomerase DNA binding, The Biochemical Journal, vol.465, 2, 2015,pp 347-357