Browsing by Author Tiffen, Jessamy

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Issue DateTitleAuthor(s)Citation
2011Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer ProgressionBailey, Charles; Holst, Jeffrey; Rasko, John; Buchanan, Grant; Hendy, Stephen; Lehman, Melanie; Minhas, Vineet; Nelson, Colleen; Ng, Cynthia; Thoeng, Annora; Tiffen, Jessamy; Wang, Qian; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteAndrogen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression, Cancer Research, vol.71, 24, 2011,pp 7525-7536
2013The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cellsBailey, Charles; Feng, Yue; Holst, Jeffrey; Marshall, Amy; Metierre, Cynthia; Rasko, John; Tiffen, Jessamy; Wang, Qian; Watson, Sarah L.; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells, International Journal of Cancer, vol.133, 7, 2013,pp 1603-1613
2015Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signalingDe Paoli-Iseppi, Ricardo; Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Strbenac, Dario; Tiffen, Jessamy; Wilmott, James; Yang, Jean Yee Hwa; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Mathematics & Statistics; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Mathematics & StatisticsCombining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling, Oncotarget, vol.6, 25, 2015,pp 21507-21521
2014Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; James, Wilmott; McArthur, Grant A.; Tummino, Peter J; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteControl of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151, Pigment Cell & Melanoma Research, vol.27, 6, 2014,pp 1126-1137
2014The Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma CellsGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteThe Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma Cells, Journal of Investigative Dermatology, vol.134, 11, 2014,pp 1523-1747
2016EZH2 as a mediator of treatment resistance in melanomaFazekas de St Groth, Barbara Denise; Gallagher, Stuart; Hersey, Peter; Tiffen, Jessamy; Tseng, Hsin-Yi; Filipp, Fabian; School of Medical Sciences: Pathology; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: Sydney Melanoma UnitEZH2 as a mediator of treatment resistance in melanoma, Pigment Cell & Melanoma Research, vol.29, 5, 2016,pp 500-507
2015EZH2: An emerging role in melanoma biology and strategies for targeted therapyGallagher, Stuart; Hersey, Peter; Tiffen, Jessamy; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteEZH2: An emerging role in melanoma biology and strategies for targeted therapy, Pigment Cell & Melanoma Research, vol.28, 1, 2015,pp 21-30
2018HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanomaBeaumont, Kimberley; Ferguson, Peter; Gallagher, Stuart; Gunatilake, Dilini; Haass, Nikolas; Heinemann, Anja; Hersey, Peter; Madore, Jason; Rizos, Helen; Sharp, Danae; Tiffen, Jessamy; Weninger, Wolfgang; Wilmott, James; Central Clinical School: Centenary Institute; Medicine; Westmead Clinical School: Medicine; Northern Clinical School: Kolling Institute; Central Clinical School: Centenary Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryHDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma, International Journal of Cancer, vol.142, 9, 2018,pp 1926-1937
2015Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune TherapyGallagher, Stuart; Hersey, Peter; Tiffen, Jessamy; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteHistone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy, Cancers, vol.7, 4, 2015,pp 1959-1982
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2010Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivoBailey, Charles; Holst, Jeffrey; Ng, Cynthia; Rasko, John; Tiffen, Jessamy; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteLuciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo, Molecular Cancer, vol.9, N/A,pp 299-1-299-8
2016Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in MelanomaGallagher, Stuart; Hersey, Peter; Tiffen, Jessamy; Filipp, Fabian; Wilson, Stephen; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteSomatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma, NeoPlasia: an international journal of oncology research, vol.18, 2, 2016,pp 121-132
2015Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genesGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Mann, Graham; Pupo, Gulietta; Strbenac, Dario; Tiffen, Jessamy; Yang, Jean Yee Hwa; Cullinane, Carleen; Dutton-Regester, Ken; Filli[, Fabian V.; Hayward, Nicholas; McArthur, Grant A.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Mathematics & Statistics; Central Clinical School: Centenary Institute; Mathematics & StatisticsTargeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes, Oncotarget, vol.6, 29, 2015,pp 27023-27036
2013Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor DevelopmentBailey, Charles; Feng, Yue; Holst, Jeffrey; Metierre, Cynthia; Rasko, John; Ritchie, William; Tiffen, Jessamy; Wang, Kevin Qian; Buchanan, Grant; Fazli, Ladan; Gleave, Martin; Lehman, Melanie; Li, Estelle; Nelson, Colleen; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteTargeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development, Journal of the National Cancer Institute, vol.105, 19, 2013,pp 1463-1473
2014Targeting glutamine transport to suppress melanoma cell growthBailey, Charles; Beaumont, Kimberley; Font Sadurni, Josep; Haass, Nikolas; Holst, Jeffrey; Jormakka, Mika; Otte, Nicholas; Rasko, John; Ryan, Renae; Sharp, Danae; Tiffen, Jessamy; van Geldermalsen, Michelle; Wang, Kevin Qian; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Molecular Bioscience; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Pharmacology; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteTargeting glutamine transport to suppress melanoma cell growth, International Journal of Cancer, vol.135, 5, 2014,pp 1060-1071
2015Targeting of cytosolic phospholipase A2a impedes cell cycle re-entry of quiescent prostate cancer cellsBao, Bob Shi San; Dong, Qihan; Holst, Jeffrey; Kiang, Mei-Yee; Teng, Ying; Tiffen, Jessamy; Wang, Kevin Qian; Witting, Paul; Xie, Chanlu; Yao, Mu; Harman, David G.; Sved, Paul; School of Medical Sciences: Pathology; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Anaesthesia; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Central Clinical School: Medicine; Central Clinical School: MedicineTargeting of cytosolic phospholipase A2a impedes cell cycle re-entry of quiescent prostate cancer cells, Oncotarget, vol.6, 33, 2015,pp 34458-34474