Browsing by Author Suryo Rahmanto, Yohan

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Issue DateTitleAuthor(s)Citation
2012Bp44mT: An Orally-Active Iron Chelator of the Thiosemicarbazone Class with Potent Anti-Tumour EfficacyRichardson, Desi (Des); Suryo Rahmanto, Yohan; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyBp44mT: An Orally-Active Iron Chelator of the Thiosemicarbazone Class with Potent Anti-Tumour Efficacy, British Journal of Pharmacology, vol.165, 1, 2012,pp 148-166
2011Cellular Iron Depletion and the Mechanisms involved in the Iron-dependent regulation of the growth arrest and DNA damage family of genesRichardson, Desi; Saletta, Federica; Siafakas, Aritee Rosemary; Suryo Rahmanto, Yohan; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyCellular Iron Depletion and the Mechanisms involved in the Iron-dependent regulation of the growth arrest and DNA damage family of genes, The Journal of biological chemistry, vol.286, 41, 2011,pp 35396-35406
2007Differential regulation of the Menkes and Wilson disease copper transporters by hormones: an integrated model of metal transport in the placentaRichardson, Desi; Suryo Rahmanto, Yohan; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDifferential regulation of the Menkes and Wilson disease copper transporters by hormones: an integrated model of metal transport in the placenta, Biochemical Journal, vol.402,(2),2007,pp e1-e3
2009Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutantBecker, Erika; Huang, Michael; Richardson, Desi (Des); Suryo Rahmanto, Yohan; Whitnall, Megan; Ponka, Prem; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical SciencesElucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant, Proceedings of the National Academy of Sciences (PNAS) of the United States of America, vol.106, 38, 2009,pp 16381-16386
2008The function of the membrane-bound transferrin homolog, melanotransferrin (melanoma tumour antigen p97)Richardson, Desi (Des); Suryo Rahmanto, Yohan; Dunn, Louise L.; Sekyere, Eric O.; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe function of the membrane-bound transferrin homolog, melanotransferrin (melanoma tumour antigen p97) in Iron Metabolism and Disease, Research Signpost, 2008, pp. 219-239
2009Generation and characterization of transgenic mice hyper-expressing melanoma tumour antigen p97 (Melanotransferrin): No overt alteration in phenotypeRichardson, Desi; Suryo Rahmanto, Yohan; School of Medical Sciences: Pathology; School of Medical Sciences: Anatomy & HistologyGeneration and characterization of transgenic mice hyper-expressing melanoma tumour antigen p97 (Melanotransferrin): No overt alteration in phenotype, B B A - Molecular Cell Research, vol.1793,(7),2009,pp 1210-1217
2013Hepcidin Bound to α2-Macroglobulin Reduces Ferroportin-1 Expression and Enhances Its Activity at Reducing Serum Iron LevelsHuang, Michael; Richardson, Desi (Des); Suryo Rahmanto, Yohan; Ponka, Prem; Sari, Marie-Agnès; Vyoral, Daniel; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyHepcidin Bound to α2-Macroglobulin Reduces Ferroportin-1 Expression and Enhances Its Activity at Reducing Serum Iron Levels, The Journal of Biological Chemistry, vol.288, 35, 2013,pp 25450-25465
2009Hepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in bloodBecker, Erika; Huang, Michael; Kuchel, Philip; Richardson, Desi (Des); Suryo Rahmanto, Yohan; Sutak, Robert; Vyoral, Daniel; Halada, Petr; Hrdy, Ivan; Kuzelova, Katerina; Peslova, Gabriela; Petrak, Jiri; Ponka, Prem; Soe-Lin, Shan; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Molecular Bioscience; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical SciencesHepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in blood, Blood, vol.113, 24, 2009,pp 6225-6236
2012Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxiaHuang, Michael; Lok, Hiu; Richardson, Desi (Des); Saletta, Federica; Suryo Rahmanto, Yohan; Whitnall, Megan; Fleming, Adam; Gutierrez, Lucia; Lazaro, Francisco; Mikhael, Marc R.; Ponka, Prem; ST Pierre, T. G.; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical SciencesIdentification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia, Proceedings of the National Academy of Sciences (PNAS), vol.109, 50, 2012,pp 20590-20595
2010The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich's ataxia.Becker, Erika; Huang, Michael; Richardson, Desi; Suryo Rahmanto, Yohan; Whitnall, Megan; Ponka, Prem; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical SciencesThe ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich's ataxia., Journal of Molecular Medicine, vol.88, 4,pp 2010-323
2009Iron Chelator-Mediated Alterations in Gene Expression: Identification of Novel Iron-Regulated Molecules that are Molecular Targets of HIF-1{alpha} and p53.Noulsri, Egarit; Richardson, Desi; Saletta, Federica; Suryo Rahmanto, Yohan; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyIron Chelator-Mediated Alterations in Gene Expression: Identification of Novel Iron-Regulated Molecules that are Molecular Targets of HIF-1{alpha} and p53., Molecular Pharmacology, vol.77, 3,pp 443-458
2012Iron chelators for the treatment of cancerGutierrez, Elaine; Kovacevic, Zaklina; Obeidy, Peyman; Richardson, Desi (Des); Saletta, Federica; Suryo Rahmanto, Yohan; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyIron chelators for the treatment of cancer, Current Medicinal Chemistry, vol.19, 17, 2012,pp 2689-2702
2008The MCK mouse heart model of Friedreich’s ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelationBecker, Erika; Richardson, Desi; Suryo Rahmanto, Yohan; Sutak, Robert; Whitnall, Megan; Xu, Xiangcong; Mikhael, Marc R.; Ponka, Prem; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; Northern Clinical School: PathologyThe MCK mouse heart model of Friedreich’s ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation, Proceedings of the National Academy of Sciences, vol.105,(28),2008,pp 9757-9762
2007The melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark - from iron metabolism to tumorigenesisDunn, Louise; Richardson, Desi; Suryo Rahmanto, Yohan; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark - from iron metabolism to tumorigenesis, Oncogene: including Oncogene Reviews, vol.26,(42),2007,pp 6113-6124
2012Melanotransferrin: Search for a functionBal, Sumeet; Loh, Kim; Richardson, Desi (Des); Suryo Rahmanto, Yohan; Yu, Yu; Medicine; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMelanotransferrin: Search for a function, Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol.1820, 3, 2012,pp 237-243
2010Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.Becker, Erika; Huang, Michael; Lane, Darius; Richardson, Desi; Suryo Rahmanto, Yohan; Ponka, Prem; Sheftel, Alex; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol., Proceedings of the National Academy of Sciences, vol.107, 24,pp 10775-10782
2013N-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron DepletionKovacevic, Zaklina; Lane, Darius; Richardson, Desi (Des); Saletta, Federica; Suryo Rahmanto, Yohan; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyN-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron Depletion, PLoS One, vol.8, 2, 2013,pp 1-15
2012Nitrogen Monoxide (NO) Storage and Transport by Dinitrosyl-Dithiol-Iron Complexes: Long-Lived NO that is Trafficked by Interacting ProteinsKalinowski, Danuta; Lane, Darius; Lok, Hiu; Richardson, Desi (Des); Richardson, Vera; Suryo Rahmanto, Yohan; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyNitrogen Monoxide (NO) Storage and Transport by Dinitrosyl-Dithiol-Iron Complexes: Long-Lived NO that is Trafficked by Interacting Proteins, JBC Papers in Press, vol.287, 10, 2012,pp 6960-6968
2006Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo.Dunn, Louise; Owusu Sekyere, Eric; Richardson, Desi; Suryo Rahmanto, Yohan; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyRole of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo., Blood, vol.107,(7),2006,pp 2599-2601
2012Siderocalin/Lcn2/NGAL/24p3 Does Not Drive Apoptosis Through Gentisic Acid Mediated Iron Withdrawal in Hematopoietic Cell LinesKovacevic, Zaklina; Richardson, Desi (Des); Richardson, Vera; Suryo Rahmanto, Yohan; Bandaranayake, Ashok D; Barasch, Jonathan; Clifton, Matthew; Correnti, Colin; Holmes, Margaret; Kaiser, Brett; Raymond, Kenneth; Ruiz, Mario; Sia, Allyson K; Strong, Roland; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologySiderocalin/Lcn2/NGAL/24p3 Does Not Drive Apoptosis Through Gentisic Acid Mediated Iron Withdrawal in Hematopoietic Cell Lines, PLoS One, vol.7, 8, 2012,pp 1-15