Browsing by Author Stokes, Leanne

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Issue DateTitleAuthor(s)Citation
2013CAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulationStokes, Leanne; Pupovac, Aleta; Sluyter, Ronald; Nepean Clinical School: MedicineCAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulation, Purinergic Signalling, vol.9, 4, 2013,pp 609-619
2009Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation.Stokes, Leanne; Surprenant, A; Nepean Clinical School: MedicineDynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation., European Journal of Immunology, vol.39, 4,pp 986-995
2009Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation.McGeachie, A; Stokes, Leanne; Wiley, James; Gu, Ben; Rathsam, Catherine; Children's Hospital Westmead: Childrens Medical Research Ins; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineExtracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation., American Journal of Physiology: Cell Physiology, vol.297, 2,pp C430-C439
2009Genetics of the P2X7 receptor and human diseaseFuller, Stephen; Gu, Baijun (Ben); Skarratt, K; Stokes, Leanne; Wiley, James; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineGenetics of the P2X7 receptor and human disease, Purinergic Signalling, vol.5,(2),2009,pp 257-262
2007Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonistShemon, Anne; Sluyter, Ronald; Stokes, Leanne; Wiley, James; Manley, Paul W; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineInhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist, Biochemical and Biophysical Research Communications (2005), vol.365,(Available online 20 November 2007),2007,pp 515-520
2011A Loss-of-Function Polymorphism in the Human P2X4 Receptor Is Associated With Increased Pulse PressureGu, Baijun (Ben); Skarratt, Kristen; Stokes, Leanne; Wiley, James; Cromer, Brett; Ellis, Justine; Harrap, Stephen B.; Scurrah, Katrina Jacqueline; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineA Loss-of-Function Polymorphism in the Human P2X4 Receptor Is Associated With Increased Pulse Pressure, Hypertension, vol.58, 6, 2011,pp 1086-1092
2014Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and MonocytesHiggins, Kathryn; Kovacevic, William; Stokes, Leanne; Nepean Clinical School: Office; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineNucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes, Mediators of Inflammation, vol.2014, N/A, 2014,pp 1-13
2015Paroxetine suppresses recombinant human P2X7 responsesDao-Ung, Phuong; Fuller, Stephen; Skarratt, Kristen; Stokes, Leanne; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineParoxetine suppresses recombinant human P2X7 responses, Purinergic Signalling, vol.11, 4, 2015,pp 481-490
2017Pharmacological evaluation of novel bioisosteres of an adamantanyl benzamide P2X7 receptor antagonistBarron, Melissa; Fuller, Stephen; Hibbs, David; Kassiou, Michael; O'Brien-Brown, James; Ong, Jennifer; Skarratt, Kristen; Werry, Eryn; Wilkinson, Shane; Chishty, Mansoor; Janssen, Bieneke; Stokes, Leanne; Vugts, Danielle J.; Windhorst, Albert D.; School of Medical Sciences: Physiology; Nepean Clinical School: Medicine; Pharmacy; Chemistry; Chemistry; Pharmacy; Nepean Clinical School: Medicine; Medical Imaging and Radiation Sciences; ChemistryPharmacological evaluation of novel bioisosteres of an adamantanyl benzamide P2X7 receptor antagonist, ACS Chemical Neuroscience, vol.8, 11, 2017,pp 2374-2380
2012Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal womenSkarratt, Kristen; Stokes, Leanne; Wiley, James; Fraser, William; Gallagher, James A.; Gartland, A.; Hocking, Lynne J; Jorgensen, Niklas Rye; Parsons, Claire; Reid, D. M.; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicinePolymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women, European Journal of Human Genetics, vol.20, 5, 2012,pp 559-564
2014Probenecid Blocks Human P2X7 Receptor-Induced Dye Uptake via a Pannexin-1 Independent MechanismBhaskaracharya, Archana; Dao-Ung, Phuong; Fuller, Stephen; Skarratt, Kristen; Stokes, Leanne; Jalilian, Iman; Sluyter, Ronald; Spildrejorde, Mari; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineProbenecid Blocks Human P2X7 Receptor-Induced Dye Uptake via a Pannexin-1 Independent Mechanism, PLoS One, vol.9, 3, 2014,pp 1-8
2014R270C polymorphism leads to loss of function of the canine P2X7 receptorSkarratt, Kristen; Stokes, Leanne; Bakhsh, Tahani; Bartlett, Rachael; Curtis, Belinda; Dowton, Mark; Jalilian, Iman; McArthur, Jason D.; Peranec, Michelle; Seavers, A; Skora, Amanda; Sluyter, Ronald; Sluyter, Vanessa; Spildrejorde, Mari; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineR270C polymorphism leads to loss of function of the canine P2X7 receptor, Physiological Genomics, vol.46, 14, 2014,pp 512-522
2013Rab5 regulates internalisation of P2X4 receptors and potentiation by ivermectinStokes, Leanne; Nepean Clinical School: MedicineRab5 regulates internalisation of P2X4 receptors and potentiation by ivermectin, Purinergic Signalling, vol.9, 1, 2013,pp 113-121
2011Significance of P2X7 Receptor Variants to Human Health and DiseaseStokes, Leanne; Sluyter, Ronald; Nepean Clinical School: MedicineSignificance of P2X7 Receptor Variants to Human Health and Disease, Recent Patents on DNA and Gene Sequences, vol.5, 1, 2011,pp 41-54
2012Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fracturesClifton-Bligh, Roderick; Fuller, Stephen; Skarratt, Kristen; Stokes, Leanne; Wiley, James; Brixen, Kim; Eiken, P; Gartland, A.; Husted, Lise; Jensen, Jens-Erik; Jorgensen, Niklas Rye; Kvist, Torben; Langdahl, Bente; Schwarz, Peter; Tofteng, Charlotte; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineSingle-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures, European Journal of Human Genetics, vol.20, 6, 2012,pp 675-681
2010Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1{beta} secretion.Fuller, Stephen; Gu, Baijun (Ben); Skarratt, Kristen; Sluyter, Ronald; Stokes, Leanne; Wiley, James; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineTwo haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1{beta} secretion., The F A S E B Journal, vol.24, 8,pp 2916-2927