Browsing by Author Smith, Susan

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Issue DateTitleAuthor(s)Citation
2016Ablation of Perlecan domain I heparan sulfate reduces progressive cartilage degradation, synovitis, and osteophyte size in post-traumatic osteoarthritisJackson, Miriam; Little, Christopher; Melrose, James; Shu, Cindy; Smith, Margaret; Smith, Susan; Lord, Megan; Penm, Steven; Whitelock, John M.; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint ResearchAblation of Perlecan domain I heparan sulfate reduces progressive cartilage degradation, synovitis, and osteophyte size in post-traumatic osteoarthritis, Arthritis & Rheumatology, vol.68, 4, 2016,pp 868-879
2005Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healingBuisson-Legendre, Nathalie; Cooper, Alan; Davey, Ross; Furphy, L; Jackson, Christopher; March, Lyn; Sambrook, Philip; Smith, Susan; Thompson, Patrick; Whitmont, K; Xue, Meilang; Sztynda, Tamara; Medicine Faculty Office; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: MedicineActivated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing, Wound Repair and Regeneration, vol.13,(3),2005,pp 284-294
2009Activation of Cartilage Matrix Metalloproteinases by Activated Protein CJackson, Christopher; Jackson, Miriam; Little, Christopher; Smith, Margaret; Smith, Susan; Xue, Meilang; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: MedicineActivation of Cartilage Matrix Metalloproteinases by Activated Protein C, Arthritis and Rheumatism, vol.60,(3),2009,pp 780-791
2007Aggrecan, versican and type VI collagen are components of annular translamellar crossbridges in the intervertebral discAppleyard, Richard; Little, Christopher; Melrose, James; Smith, Susan; Medicine; Northern Clinical School: Surgery; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint ResearchAggrecan, versican and type VI collagen are components of annular translamellar crossbridges in the intervertebral disc, European Spine Journal, vol.Published online: 31 October 2007,(N/A),2007,pp N/A-N/A
2013Altered stress induced by partial transection of the infraspinatus tendon leads to perlecan (HSPG2) accumulation in an ovine model of tendinopathyDart, Andrew; Little, Christopher; Melrose, James; Ravi, Varshini; Smith, Margaret; Smith, Susan; Sonnabend, David; Young, A; Vet Science Faculty; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: SurgeryAltered stress induced by partial transection of the infraspinatus tendon leads to perlecan (HSPG2) accumulation in an ovine model of tendinopathy, Tissue and Cell, vol.45, 1, 2013,pp 77-82
2003Assessment of the cellular heterogeneity of the ovine intervertebral disc: comparison with synovial fibroblasts and articular chondrocytesGhosh, Peter; Melrose, James; Smith, Susan; Northern Clinical School: Surgery; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint ResearchAssessment of the cellular heterogeneity of the ovine intervertebral disc: comparison with synovial fibroblasts and articular chondrocytes, European Spine Journal, vol.12,(1),2003,pp 57-65
2007Biglycan and fibromodulin fragmentation correlates with temporal and spatial annular remodelling in experimentally injured ovine intervertebral discsDart, Andrew; Fuller, Emily; Little, Christopher; Melrose, James; Smith, Susan; Young, Allan; Roughley, Peter J; Vet Science Faculty; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Surgery; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: MedicineBiglycan and fibromodulin fragmentation correlates with temporal and spatial annular remodelling in experimentally injured ovine intervertebral discs, European Spine Journal, vol.16,(12),2007,pp 2193-2205
2007Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repairLittle, Christopher; Smith, Susan; Farmer, Pamela J.; Fosang, Amanda J.; Golub, Suzanne; Lawlor, Kate E.; Meeker, Clare T.; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint ResearchBlocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair, Journal of Clinical Investigation, vol.117,(6),2007,pp 1627-1636
2012Chondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint developmentLittle, Christopher; Melrose, James; Smith, Susan; Caterson, Bruce; Hayes, Anthony; Hughes, Clare E.; Isaacs, Marc; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint ResearchChondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint development, Histochemistry and Cell Biology, vol.138, 3, 2012,pp 461-475
2011Colocalization in vivo and association in vitro of perlecan and elastinMelrose, James; Smith, Margaret; Smith, Susan; Weiss, Anthony; Hayes, Anthony; Lord, Megan; Whitelock, John M.; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Molecular BioscienceColocalization in vivo and association in vitro of perlecan and elastin, Histochemistry and Cell Biology, vol.136, N/A, 2011,pp 437-454
2013Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral discMelrose, James; Smith, Susan; Hayes, Anthony; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint ResearchComparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc, Histochemistry and Cell Biology, vol.139, 1, 2013,pp 1-11
2010Comparative immunolocalisation of perlecan with collagen II and aggrecan in human foetal, newborn and adult ovine joint tissues demonstrates perlecan as an early developmental chondrogenic markerMelrose, James; Shu, Cindy; Smith, Susan; Northern Clinical School: SurgeryComparative immunolocalisation of perlecan with collagen II and aggrecan in human foetal, newborn and adult ovine joint tissues demonstrates perlecan as an early developmental chondrogenic marker, Histochemistry and Cell Biology, vol.134, 3,pp 251-263
2013Comparative immunolocalisation of perlecan, heparan sulphate, fibroblast growth factor-18, and fibroblast growth factor receptor-3 and their prospective roles in chondrogenic and osteogenic development of the human foetal spineLittle, Christopher; Melrose, James; Shu, Cindy; Smith, Susan; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint ResearchComparative immunolocalisation of perlecan, heparan sulphate, fibroblast growth factor-18, and fibroblast growth factor receptor-3 and their prospective roles in chondrogenic and osteogenic development of the human foetal spine, European Spine Journal, vol.22, 8, 2013,pp 1774-1784
2016The CS Sulphation Motifs 4C3, 7D4, 3B3[-]; and Perlecan Identify Stem Cell Populations and Niches, Activated Progenitor Cells and Transitional Tissue Development in the Fetal Human ElbowLittle, Christopher; Melrose, James; Smith, Susan; Caterson, Bruce; Hayes, Anthony; Hughes, Clare E.; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint ResearchThe CS Sulphation Motifs 4C3, 7D4, 3B3[-]; and Perlecan Identify Stem Cell Populations and Niches, Activated Progenitor Cells and Transitional Tissue Development in the Fetal Human Elbow, Stem Cells and Development, vol.25, 11, 2016,pp 836-847
2014Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanismsJackson, Christopher; Jackson, Miriam; Little, Christopher; McCracken, Sharon Anne; Moradi, Babak; Smith, Margaret; Smith, Susan; Zaki, Sanaa; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Vet Science FacultyDepletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms, Arthritis & Rheumatology, vol.66, 12, 2014,pp 3337-3348
2016The heparan sulphate deficient Hspg2 exon 3 null mouse displays reduced deposition of TGF-Beta1 in skin compared to C57BL/6 wild type miceMelrose, James; Shu, Cindy; Smith, Susan; Northern Clinical School: SurgeryThe heparan sulphate deficient Hspg2 exon 3 null mouse displays reduced deposition of TGF-Beta1 in skin compared to C57BL/6 wild type mice, Journal of Molecular Histology, vol.47, 3, 2016,pp 365-374
2016Immunolocalization and distribution of proteoglycans in carious dentineBertassoni, Luiz; Little, Christopher; Sarram, Leila; Smith, Susan; Stankoska, Katerina; Swain, Michael; Bedran-Russo, A; Dentistry Faculty; Northern Clinical School: Kolling Institute; Dentistry Faculty; Northern Clinical School: Inst. for Bone & Joint Research; Dentistry Faculty; Dentistry FacultyImmunolocalization and distribution of proteoglycans in carious dentine, Australian Dental Journal, vol.61, 3, 2016,pp 288-297
2016Immunolocalization and distribution of proteoglycans in carious dentineBertassoni, Luiz; Little, Christopher; Sarram, Leila; Smith, Susan; Stankoska, Katerina; Swain, Michael; Bedran-Russo, A; Dentistry Faculty; Northern Clinical School: Kolling Institute; Dentistry Faculty; Northern Clinical School: Inst. for Bone & Joint Research; Dentistry Faculty; Dentistry FacultyImmunolocalization and distribution of proteoglycans in carious dentine, Australian Dental Journal, vol.61, 3, 2016,pp 288-297
2011Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritisChan, Benjamin; Fuller, Emily; Jackson, Miriam; Little, Christopher; Russell, A; Sambrook, Philip; Smith, Margaret; Smith, Susan; Bateman, John F; Cake, M A; Read, R. A.; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint ResearchIncreased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis, Osteoarthritis and Cartilage, vol.19, 7, 2011,pp 874-885
2009Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte developmentBarai, Ashutosh; Burkhardt, Daniel; Little, Christopher; Smith, Susan; Fosang, A; Shah, M; Thompson, Erik Walter; Werb, Z; Northern Clinical School: Surgery; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint ResearchMatrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development, Arthritis Care and Research, vol.60, 12,pp 3723-3733