Browsing by Author Smith, Margaret

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Issue DateTitleAuthor(s)Citation
2016Ablation of Perlecan domain I heparan sulfate reduces progressive cartilage degradation, synovitis, and osteophyte size in post-traumatic osteoarthritisJackson, Miriam; Little, Christopher; Melrose, James; Shu, Cindy; Smith, Margaret; Smith, Susan; Lord, Megan; Penm, Steven; Whitelock, John M.; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint ResearchAblation of Perlecan domain I heparan sulfate reduces progressive cartilage degradation, synovitis, and osteophyte size in post-traumatic osteoarthritis, Arthritis & Rheumatology, vol.68, 4, 2016,pp 868-879
2009Activated protein C mediates a healing phenotype in cultured tenocytesJackson, Christopher; Little, Christopher; March, Lyn; Sambrook, Philip; Smith, Margaret; Xue, Meilang; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: MedicineActivated protein C mediates a healing phenotype in cultured tenocytes, Journal of Cellular and Molecular Medicine, vol.13,(4),2009,pp 749-757
2009Activation of Cartilage Matrix Metalloproteinases by Activated Protein CJackson, Christopher; Jackson, Miriam; Little, Christopher; Smith, Margaret; Smith, Susan; Xue, Meilang; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: MedicineActivation of Cartilage Matrix Metalloproteinases by Activated Protein C, Arthritis and Rheumatism, vol.60,(3),2009,pp 780-791
2014Activation of matrix metalloproteinases 2, 9, and 13 by activated protein c in human osteoarthritic cartilage chondrocytesBabak, Moradi; Jackson, Christopher; Jackson, Miriam; Little, Christopher; Smith, Margaret; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint ResearchActivation of matrix metalloproteinases 2, 9, and 13 by activated protein c in human osteoarthritic cartilage chondrocytes, Arthritis & Rheumatology, vol.66, 6, 2014,pp 1525-1536
2013Altered stress induced by partial transection of the infraspinatus tendon leads to perlecan (HSPG2) accumulation in an ovine model of tendinopathyDart, Andrew; Little, Christopher; Melrose, James; Ravi, Varshini; Smith, Margaret; Smith, Susan; Sonnabend, David; Young, A; Vet Science Faculty; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: SurgeryAltered stress induced by partial transection of the infraspinatus tendon leads to perlecan (HSPG2) accumulation in an ovine model of tendinopathy, Tissue and Cell, vol.45, 1, 2013,pp 77-82
2003Biosensor analysis of the molecular interactions of pentosan polysulfate and of sulfated glycosaminoglycans with immobilized elastase, hyaluronidase and lysozyme using surgace plasmon resonance (SPR) technologyGhosh, Peter; Shen, B; Shimmon, Susan; Smith, Margaret; Northern Clinical School: Surgery; Surgery; Central Clinical School: Surgery; Applied Vision SciencesBiosensor analysis of the molecular interactions of pentosan polysulfate and of sulfated glycosaminoglycans with immobilized elastase, hyaluronidase and lysozyme using surgace plasmon resonance (SPR) technology, Journal of Pharmaceutical and Biomedical Analysis, vol.31,(1),2003,pp 83-93
2009Cell biological and biomechanical evaluation of two different fixation techniques for rotator cuff repair.Smith, Margaret; Baums, M; Kahl, E; Klinger, H; Koelling, S; Miosge, N; Schultz, W; Steckel, H; Northern Clinical School: Inst. for Bone & Joint ResearchCell biological and biomechanical evaluation of two different fixation techniques for rotator cuff repair., Scandinavian Journal Of Medicine & Science In Sports, vol.19, 3,pp 329-337
2008Changes in gait after bilateral meniscectomy in sheep: effect of two hyaluronan preparationsBurkhardt, Daniel; Ghosh, Peter; Little, Christopher; Smith, Margaret; Cake, M A; Edwards, Scott; Read, R. A.; Northern Clinical School: Surgery; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint ResearchChanges in gait after bilateral meniscectomy in sheep: effect of two hyaluronan preparations, Journal of orthopaedic science, vol.13, 6, 2008,pp 514-523
2016Chondroitin sulphate glycosaminoglycans contribute to widespread inferior biomechanics in tendon after focal injuryChoi, Rachel; Clarke, Elizabeth Clare; Clarke, Jillian; Dart, Andrew; Little, Christopher; Martin, Joshua; Smith, Margaret; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Medical Imaging and Radiation Sciences; Vet Science Faculty; Northern Clinical School: Kolling Institute; Aerospace Mech & Mtronic Eng; Northern Clinical School: Inst. for Bone & Joint ResearchChondroitin sulphate glycosaminoglycans contribute to widespread inferior biomechanics in tendon after focal injury, Journal of Biomechanics, vol.49, N/A, 2016,pp 2694-2701
2011Colocalization in vivo and association in vitro of perlecan and elastinMelrose, James; Smith, Margaret; Smith, Susan; Weiss, Anthony; Hayes, Anthony; Lord, Megan; Whitelock, John M.; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Molecular BioscienceColocalization in vivo and association in vitro of perlecan and elastin, Histochemistry and Cell Biology, vol.136, N/A, 2011,pp 437-454
2013Comparison of gait and pathology outcomes of three meniscal procedures for induction of knee osteoarthritis in sheepBurkhardt, Daniel; Little, Christopher; Smith, Margaret; Cake, M A; Corfield, G; Daniel, A; Read, R. A.; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint ResearchComparison of gait and pathology outcomes of three meniscal procedures for induction of knee osteoarthritis in sheep, Osteoarthritis and Cartilage, vol.21, 1, 2013,pp 226-236
2017Considerations for the Design and Execution of Protocols for Animal Research and Treatment to improve reproducibility and standardization: "DEPART well-prepared and ARRIVE safely"Clarke, Elizabeth Clare; Little, Christopher; Smith, Margaret; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint ResearchConsiderations for the Design and Execution of Protocols for Animal Research and Treatment to improve reproducibility and standardization: "DEPART well-prepared and ARRIVE safely", Osteoarthritis and Cartilage, vol.25, 3, 2017,pp 354-363
2016Contamination of the surgical field with propionibacterium acnes in primary shoulder arthroplastySmith, Margaret; Baba, Mohammed; Cass, Benjamin; Donaldson, Matthew J; Dorrestijn, Oscar; Falconer, Travis M; Figtree, Melanie; Hudson, Bernard J; Kruse, Lisa M; Young, Allan A; Northern Clinical School: Inst. for Bone & Joint ResearchContamination of the surgical field with propionibacterium acnes in primary shoulder arthroplasty, Journal of Bone and Joint Surgery: American Volume, vol.98, 20, 2016,pp 1722-1728
2014Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanismsJackson, Christopher; Jackson, Miriam; Little, Christopher; McCracken, Sharon Anne; Moradi, Babak; Smith, Margaret; Smith, Susan; Zaki, Sanaa; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Inst. for Bone & Joint Research; Vet Science FacultyDepletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms, Arthritis & Rheumatology, vol.66, 12, 2014,pp 3337-3348
2017Does knee malalignment predict the efficacy of realignment therapy for patients with knee osteoarthritis?Hunter, David; Rezaeian, Zahra Sadat; Gross, Kevin; Harvey, William; Skaife, Tyler; Smith, Margaret; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling InstituteDoes knee malalignment predict the efficacy of realignment therapy for patients with knee osteoarthritis?, International Journal of Rheumatic Diseases, vol.20, 10, 2017,pp 1403-1412
2007Dynamic Biomechanics Correlate With Histopathology in Human Tibial Cartilage: A Preliminary StudyAppleyard, Richard; Little, Christopher; Melrose, James; Smith, Margaret; Young, Allan; Medicine; Northern Clinical School: Surgery; Northern Clinical School: Surgery; Surgery; Northern Clinical School: MedicineDynamic Biomechanics Correlate With Histopathology in Human Tibial Cartilage: A Preliminary Study, Clinical Orthopaedics and Related Research, vol.462,(N/A),2007,pp 212-220
2011Early results of reverse shoulder arthroplasty in patients with rheumatoid arthritisSmith, Margaret; Bacle, Guillaume; Moraga, Claudio; Walch, Gilles; Young, Allan A.; Northern Clinical School: Inst. for Bone & Joint ResearchEarly results of reverse shoulder arthroplasty in patients with rheumatoid arthritis, Journal of Bone and Joint Surgery: American Volume, vol.93, 20, 2011,pp 1915-1923
2005Effects of pentosan polysulfate in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled pilot studyGhosh, Peter; March, Lyn; Smith, Margaret; Edelman, Jack; Northern Clinical School: Surgery; Northern Clinical School: Medicine; Applied Vision SciencesEffects of pentosan polysulfate in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled pilot study, Current Therapeutic Research-Clinical and Experimental 2005, vol.66,(6),2005,pp 552-571
2015Focal experimental injury leads to widespread gene expression and histologic changes in equine flexor tendonsDart, Andrew; Horadagoda, Neil; Jacobsen, Else; Jeffcott, Leo; Little, Christopher; Mondori, Takamitsu; Smith, Margaret; Vet Science Faculty; Vet Science Faculty; Vet Science Faculty; Vet Science Faculty; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Inst. for Bone & Joint ResearchFocal experimental injury leads to widespread gene expression and histologic changes in equine flexor tendons, PloS One, vol.10, 4, 2015,pp 1-25
2008Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissuesFuller, Emily; Little, Christopher; Melrose, James; Smith, Margaret; Caterson, Bruce; Hughes, Clare; Kerr, Briedgeen; Roughley, Peter; Northern Clinical School: Inst. for Bone & Joint Research; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Inst. for Bone & Joint ResearchFragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues, Arthritis Research and Therapy, vol.10, doi:10.1186/ar2453, 2008,pp 1-10