Browsing by Author Sharpe, Philip C.

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Issue DateTitleAuthor(s)Citation
20092-Acetylpyridine Thiosemicarbazones are Potent Iron Chelators and Antiproliferative Agents: Redox Activity, Iron Complexation and Characterization of their Antitumor ActivityKalinowski, Danuta; Lovejoy, David; Richardson, Desi; Richardson, Vera; Bernhardt, Paul V.; Islam, Mohammad; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute2-Acetylpyridine Thiosemicarbazones are Potent Iron Chelators and Antiproliferative Agents: Redox Activity, Iron Complexation and Characterization of their Antitumor Activity, Journal of Medicinal Chemistry, vol.52,(5),2009,pp 1459-1470
2006Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity.Kalinowski, Danuta; Lovejoy, David; Richardson, Desi; Bernhardt, Paul V.; Islam, Mohammad; Senaratne, Dakshita; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity., Journal of Medicinal Chemistry, vol.49,(22),2006,pp 6510-6521
2011Halogenated 2'-Benzoylpyridine Thiosemicarbazone (XBpT) Chelators with Potent and Selective Anti-Neoplastic Activity: Relationship to Intracellular Redox Activity.Jansson, Jan; Kalinowski, Danuta; Lovejoy, David; Punnia-Moorthy, Armugan; Richardson, Desi; Stefani, Christian; Bernhardt, Paul V.; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Dentistry Faculty; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyHalogenated 2'-Benzoylpyridine Thiosemicarbazone (XBpT) Chelators with Potent and Selective Anti-Neoplastic Activity: Relationship to Intracellular Redox Activity., Journal of Medicinal Chemistry, vol.54, 19, 2011,pp 6936-6948
2009Iron Chelators of the Dipyridylketone Thiosemicarbazone Class: Precomplexation and Transmetalation Effects on Anticancer ActivityKalinowski, Danuta; Lovejoy, David; Richardson, Desi; Bernhardt, Paul V.; Islam, Mohammad; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyIron Chelators of the Dipyridylketone Thiosemicarbazone Class: Precomplexation and Transmetalation Effects on Anticancer Activity, Journal of Medicinal Chemistry, vol.52,(2),2009,pp 407-415
2012Methemoglobin Formation by Triapine, Di-2-pyridylketone-4,4-dimethyl-3- thiosemicarbazone (Dp44mT), and Other Anticancer Thiosemicarbazones: Identification of Novel Thiosemicarbazones and Therapeutics That Prevent This EffectGutierrez, Elaine; Jansson, Jan (Patric); Kalinowski, Danuta; Lovejoy, David; Quach, Patricia; Richardson, Desi (Des); Basha, Maram; Bernhardt, Paul V.; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMethemoglobin Formation by Triapine, Di-2-pyridylketone-4,4-dimethyl-3- thiosemicarbazone (Dp44mT), and Other Anticancer Thiosemicarbazones: Identification of Novel Thiosemicarbazones and Therapeutics That Prevent This Effect, Molecular Pharmacology, vol.82, 1, 2012,pp 105-114
2010Novel Thiosemicarbazones of the ApT and DpT Series and Their Copper Complexes: Identification of Pronounced Redox Activity and Characterization of Their Antitumor ActivityJansson, Patric; Richardson, Desi (Des); Bernhardt, Paul V.; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyNovel Thiosemicarbazones of the ApT and DpT Series and Their Copper Complexes: Identification of Pronounced Redox Activity and Characterization of Their Antitumor Activity, Journal of Medicinal Chemistry, vol.53, 15, 2010,pp 5759-5769
2008Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone seriesKalinowski, Danuta; Richardson, Desi (Des); Bernhardt, Paul V.; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyStructure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone series, Journal of Medicinal Chemistry, vol.51, 2, 2008,pp 331-344