Browsing by Author Sahni, Sumit

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Issue DateTitleAuthor(s)Citation
2015Adenosine Monophosphate-Activated Kinase and Its Key Role in Catabolism: Structure, Regulation, Biological Activity and Pharmacological ActivationKrishan, Sukriti; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; MedicineAdenosine Monophosphate-Activated Kinase and Its Key Role in Catabolism: Structure, Regulation, Biological Activity and Pharmacological Activation, Molecular Pharmacology, vol.87, 3, 2015,pp 363-377
2014AMP kinase (PRKAA1)Krishan, Sukriti; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineAMP kinase (PRKAA1), Journal of Clinical Pathology, vol.67, 9, 2014,pp 758-763
2016The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer CellsKrishan, Sukriti; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells, Biochimica et Biophysica Acta, vol.1863, 12, 2016,pp 2916-2933
2015Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in diseaseBae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineCellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease, Biochimica et Biophysica Acta. General Subjects, vol.1853, 5, 2015,pp 1130-1144
2013Cellular Uptake of the Antitumor Agent Dp44mT Occurs via a Carrier/Receptor-Mediated MechanismKalinowski, Danuta; Menezes, Sharleen; Merlot, Angelica; Pantarat, Namfon; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Bosch Institute; Western Clinical School: Westmead Millennium Institute; School of Medical Sciences: Pathology; MedicineCellular Uptake of the Antitumor Agent Dp44mT Occurs via a Carrier/Receptor-Mediated Mechanism, Molecular Pharmacology, vol.84, 6, 2013,pp 911-924
2015Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes multidrug resistance by a novel mechanism involving the hijacking of lysosomal P-Glycoprotein (Pgp)Arvind, Akanksha; Gutierrez, Elaine; Jansson, Patric; Maleki, Sanaz; Richardson, Desi (Des); Sahni, Sumit; Seebacher, Nicole; Sharp, Danae; Stacy, Alexandra Elizabeth; Yamagishi, Tetsuo; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Northern Clinical School: Kolling Institute; School of Medical Sciences: Pathology; Medicine; Biological Sciences; Central Clinical School: Medicine; School of Medical Sciences: Pathology; School of Medical Sciences: School of Medical SciencesDi-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes multidrug resistance by a novel mechanism involving the hijacking of lysosomal P-Glycoprotein (Pgp), The Journal of Biological Chemistry, vol.290, 15, 2015,pp 9588-9603
2015Duodenal cytochrome b (DCYTB) in Iron metabolism: An update on function and regulationBae, Dong-Hun; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desmond; Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pharmacology; School of Medical Sciences: PathologyDuodenal cytochrome b (DCYTB) in Iron metabolism: An update on function and regulation, Nutrients, vol.7, 4, 2015,pp 2274-2296
2016Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxiaChiang, Shannon; Huang, Michael; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyFrataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia, Clinical Science, vol.130, 11, 2016,pp 853-870
2014Glutathione S-Transferase and MRP1 Form an Integrated System Involved in the Storage and Transport of Dinitrosyl-Dithiolato Iron Complexes in CellsKalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Lok, Hiu; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; MedicineGlutathione S-Transferase and MRP1 Form an Integrated System Involved in the Storage and Transport of Dinitrosyl-Dithiolato Iron Complexes in Cells, Free Radical Biology and Medicine, vol.75, N/A, 2014,pp 14-29
2015In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites.Kalinowski, Danuta; Richardson, Desi (Des); Sahni, Sumit; et al, Various; Haskova, Pavlina; Jansova, Hana; Jirkovska, Anna; Machacek, Miloslav; Potuckova, Eliska; Roh, Jaroslav; Sestak, Vit; Stariat, Jan; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyIn Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites., PloS One, vol.10, 10, 2015,pp 1-20
2017Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signalingKovacevic, Zaklina; Menezes, Sharleen; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyInterplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling, The Journal of Biological Chemistry, vol.292, 31, 2017,pp 12772-12782
2016Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT)Arzuman, Laila; Gutierrez, Elaine; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Lok, Hiu; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Seebacher, Nicole; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Biological SciencesLysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), BBA: Biochimica et Biophysica Acta - Molecular Cell Research, vol.1863, 7 Pt A, 2016,pp 1665-1681
2016Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinaseJansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Shafie, Nurul; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinase, Biochemical Pharmacology, vol.109, N/A, 2016,pp 27-47
2016Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinaseJansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Shafie, Nurul; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinase, Biochemical Pharmacology, vol.109, N/A, 2016,pp 27-47
2017The mechanistic role of chemically diverse metal ions in the induction of autophagyBae, Dong-Hun; Jansson, Patric; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe mechanistic role of chemically diverse metal ions in the induction of autophagy, Pharmacological Research, vol.119, N/A, 2017,pp 118-127
2014The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cellsBae, Dong-Hun; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; MedicineThe metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells, The Journal of Biological Chemistry, vol.289, 14, 2014,pp 9692-9709
2016The metastasis suppressor, N-MYC downstream-regulated gene-1 (NDRG1), down-regulates the ErbB family of receptors to inhibit downstream oncogenic signaling pathwaysBae, Dong-Hun; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Menezes, Sharleen; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe metastasis suppressor, N-MYC downstream-regulated gene-1 (NDRG1), down-regulates the ErbB family of receptors to inhibit downstream oncogenic signaling pathways, Journal of Biological Chemistry, vol.291, 3, 2016,pp 1029-1052
2013Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motorsBae, Dong-Hun; Jansson, Jan (Patric); Kovacevic, Zaklina; Richardson, Desi (Des); Sahni, Sumit; Sun, Jing; Zhang, Daohai; Yue, Fei; Zhao, Qian; Zheng, Minhua; Zheng, Ying; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Medicine; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMetastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors, Carcinogenesis, vol.34, 9, 2013,pp 1943-1954
2015The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targetsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Jin, Runsen; Liu, Wensheng; Peng, Zhihai; Wang, Puxiongzhi; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targets, Oncotarget, vol.6, 34, 2015,pp 35522-35541
2015The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targetsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Jin, Runsen; Liu, Wensheng; Peng, Zhihai; Wang, Puxiongzhi; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targets, Oncotarget, vol.6, 34, 2015,pp 35522-35541