Browsing by Author Ryan, Renae

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Issue DateTitleAuthor(s)Citation
2004Allosteric Modulation Of Neurotransmitter Transporters At Excitatory SynapsesAubrey, Karin; Ju, Pengchu; Mitrovic, Ann; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyAllosteric Modulation Of Neurotransmitter Transporters At Excitatory Synapses, European Journal of Pharmaceutical Sciences, vol.23,(1),2004,pp 1-11
2017The amino acid transporter SLC1A3 is plasma membrane-localised in adipocytes and its activity is insensitive to insulinBurchfield, James; Cater, Rosemary; Fazakerley, Daniel; Humphrey, Sean; James, David; Krycer, James; Naghiloo, Sheyda; Ryan, Renae; Thomas, Kristen; Vandenberg, Robert; School of Life and Environmental Sciences (SOLES); School of Medical Sciences: Pharmacology; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Molecular Bioscience (SMB); School of Medical Sciences: Pharmacology; School of Life and Environmental Sciences (SOLES); School of Medical Sciences: PharmacologyThe amino acid transporter SLC1A3 is plasma membrane-localised in adipocytes and its activity is insensitive to insulin, FEBS Letters, vol.591, 2, 2017,pp 322-330
2018Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathwaysFreidman, Natasha; Guan, Yi; Holst, Jeffrey; Krycer, James; Pang, Angel; Quek, Lake-Ee; Ryan, Renae; Van Geldermalsen, Michelle; Wang, Qian; Turner, Nigel; School of Medical Sciences: Pharmacology; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; School of Life and Environmental Sciences (SOLES); Central Clinical School: Centenary Institute; Mathematics & Statistics; School of Medical Sciences: Pharmacology; Medicine; Clinical NursingBenzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways, BMC Cancer, vol.18, 1, 2018,pp 689 - 1-689 - 14
2005A channel in a transporter.Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyA channel in a transporter., Clinical and Experimental Pharmacology & Physiology, vol.32,(1-2),2005,pp 1-6
2016Characterization of the Inward- and Outward-Facing Substrate Binding Sites of the Prokaryotic Aspartate Transporter, GltPhMcIlwain, Benjamin; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyCharacterization of the Inward- and Outward-Facing Substrate Binding Sites of the Prokaryotic Aspartate Transporter, GltPh, Biochemistry, vol.55, 49, 2016,pp 6801-6810
2016Characterization of the Inward- and Outward-Facing Substrate Binding Sites of the Prokaryotic Aspartate Transporter, GltPhMcIlwain, Benjamin; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyCharacterization of the Inward- and Outward-Facing Substrate Binding Sites of the Prokaryotic Aspartate Transporter, GltPh, Biochemistry, vol.55, 49, 2016,pp 6801-6810
2004The Chloride Permeation Pathway Of A Glutamate Transporter And Its Proximity To The Glutamate Translocation Pathway.Mitrovic, Ann; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyThe Chloride Permeation Pathway Of A Glutamate Transporter And Its Proximity To The Glutamate Translocation Pathway., Journal of Biological Chemistry, vol.279,(20),2004,pp 20742-20751
2015Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPKMunoz, Lenka; Ryan, Renae; Chalmers, David; Devine, Shane; Krum, Henry; Scammells, Peter J.; Simpson, Jamie; Vinh, Natalie; Wang, Bing; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyDesign, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK, ChemistryOpen, vol.4, 1, 2015,pp 56-64
2013Directed Mutagenesis in Structure Activity Studies of Neurotransmitter TransportersCarland, Jane; Edington, Amelia; Ryan, Renae; Scopelliti, Amanda J; Vandenberg, Robert; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PharmacologyDirected Mutagenesis in Structure Activity Studies of Neurotransmitter Transporters in Genetic Manipulation of DNA and Protein - Examples from Current Research, InTech Publishers, 2013, pp. 167-184
2002Distinct conformational states mediate the transport and anion channel properties of the glutamate transporter EAAT-1Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyDistinct conformational states mediate the transport and anion channel properties of the glutamate transporter EAAT-1, Journal of Biological Chemistry, vol.277, 16,pp 13494-13500
2014The Domain Interface of the Human Glutamate Transporter EAAT1 Mediates Chloride PermeationCater, Rosemary; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyThe Domain Interface of the Human Glutamate Transporter EAAT1 Mediates Chloride Permeation, Biophysical Journal, vol.107, 3, 2014,pp 621-629
2004Effects Of Sumatriptan On Rat Medullary Dorsal Horn NeuronsChristie, MacDonald; Jennings, Ernest; Ryan, Renae; Northern Clinical School: Anaesthesia; Biological Sciences; School of Medical Sciences: PharmacologyEffects Of Sumatriptan On Rat Medullary Dorsal Horn Neurons, Pain, vol.111,(1-2),2004,pp 30-37
2009Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transportEdington, Amelia; Kassiou, Michael; McKinzie, Audra; Reynolds, Aaron; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; Medical Imaging and Radiation Sciences; School of Medical Sciences: Pharmacology; Chemistry; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyExtracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport, Journal of Biological Chemistry, vol.284, 52,pp 36424-36430
2014Glycine transport inhibitors for the treatment of painCarland, Jane; Christie, MacDonald; Imlach, Wendy Louise; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyGlycine transport inhibitors for the treatment of pain, Trends In Pharmacological Sciences, vol.35, 8, 2014,pp 423-430
2016Glycine Transporter2 Inhibitors: Getting the balance rightCarland, Jane; Mostyn, Shannon; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; Medicine; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyGlycine Transporter2 Inhibitors: Getting the balance right, Neurochemistry International, vol.98, N/A, 2016,pp 89-93
2016Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2Carland, Jane; Ryan, Renae; Scopelitti, Amanda; Vandenberg, Robert; O'Mara, Megan; Subramanian, Nandhitha; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: PharmacologyIdentification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2, PloS One, vol.11, 6, 2016,pp 1-16
2014Lipid Inhibitors of High Affinity Glycine Transporters: Identification of a novel class of analgesicsCarland, Jane; Handford, Cheryl; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyLipid Inhibitors of High Affinity Glycine Transporters: Identification of a novel class of analgesics, Neurochemistry International, vol.73, N/A, 2014,pp 211-216
2013Mechanisms of glutamate transportRyan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyMechanisms of glutamate transport, Physiological Reviews, vol.93, 4, 2013,pp 1621-1657
2013Molecular Determinants for Functional Differences between Alanine-Serine-Cysteine Transporter 1 and Other Glutamate Transporter Family MembersRyan, Renae; Scopelliti, Amanda J; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PharmacologyMolecular Determinants for Functional Differences between Alanine-Serine-Cysteine Transporter 1 and Other Glutamate Transporter Family Members, The Journal of Biological Chemistry, vol.288, 12, 2013,pp 8250-8257
2014Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell GrowthBailey, Charles; Font Sadurni, Josep; Holst, Jeffrey; Jormakka, Mika; Moran, Anne; Rasko, John; Ryan, Renae; Wang, Kevin Qian; Bonham, Sarah; Grkovic, Tanja; Pouwer, Rebecca; Quinn, Ronald; Central Clinical School: Centenary Institute; Molecular Bioscience; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Pharmacology; Central Clinical School: Centenary InstituteMonoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth, ACS Chemical Biology, vol.9, 6, 2014,pp 1369-1376