Browsing by Author Rawling, Tristan

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Issue DateTitleAuthor(s)Citation
2013Anti-proliferative actions of N'-desmethylsorafenib in human breast cancer cellsBourget, Kirsi; Cui, Pei-Hong; Gillani, Tina; Murray, Michael; Rawling, Tristan; Wang, Xiao; Zhou, Fanfan; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Bosch Institute; PharmacyAnti-proliferative actions of N'-desmethylsorafenib in human breast cancer cells, Biochemical Pharmacology, vol.86, 3, 2013,pp 419-427
2015Anti-tumor activities of lipids and lipid analogues and their development as potential anticancer drugsHraiki, Adam; Murray, Michael; Bebawy, Mary; Pazderka, Curtis; Rawling, Tristan; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyAnti-tumor activities of lipids and lipid analogues and their development as potential anticancer drugs, Pharmacology & Therapeutics, vol.150, N/A, 2015,pp 109-128
2012Antiproliferative and Antimigratory Actions of Synthetic Long Chain n-3 Monounsaturated Fatty Acids in Breast Cancer Cells That Overexpress Cyclooxygenase-2Bourget, Kirsi; Cui, Pei (Sarah); Doddareddy, Munikumar; Duke, Colin; Hibbs, David; Kim, Terry; Murray, Michael; Rawling, Tristan; Tattam, Bruce; Zhou, Fanfan; Petrovic, Nenad; Pharmacy; Pharmacy; School of Medical Sciences: Brain & Mind Research Institute; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyAntiproliferative and Antimigratory Actions of Synthetic Long Chain n-3 Monounsaturated Fatty Acids in Breast Cancer Cells That Overexpress Cyclooxygenase-2, Journal of Medicinal Chemistry, vol.55, 16, 2012,pp 7163-7172
2018Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell DeathBourget, Kirsi; Koolaji, Nooshin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyCarboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death, ChemMedChem: chemistry enabling drug discovery, vol.13, 10, 2018,pp 1036-1043
2018Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell DeathBourget, Kirsi; Koolaji, Nooshin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyCarboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death, ChemMedChem: chemistry enabling drug discovery, vol.13, 10, 2018,pp 1036-1043
2018Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell DeathBourget, Kirsi; Koolaji, Nooshin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyCarboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death, ChemMedChem: chemistry enabling drug discovery, vol.13, 10, 2018,pp 1036-1043
2018Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell DeathBourget, Kirsi; Koolaji, Nooshin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyCarboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death, ChemMedChem: chemistry enabling drug discovery, vol.13, 10, 2018,pp 1036-1043
2018Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell DeathBourget, Kirsi; Koolaji, Nooshin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyCarboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death, ChemMedChem: chemistry enabling drug discovery, vol.13, 10, 2018,pp 1036-1043
2018Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell DeathBourget, Kirsi; Koolaji, Nooshin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyCarboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death, ChemMedChem: chemistry enabling drug discovery, vol.13, 10, 2018,pp 1036-1043
2018Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell DeathBourget, Kirsi; Koolaji, Nooshin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyCarboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death, ChemMedChem: chemistry enabling drug discovery, vol.13, 10, 2018,pp 1036-1043
2013Cell-Derived Microparticles: New Targets in the Therapeutic Management of DiseaseGrau, Georges; Bebawy, Mary; Luk, Frederick; Rawling, Tristan; Roseblade, Ariane; Ung, Alison; School of Medical Sciences: PathologyCell-Derived Microparticles: New Targets in the Therapeutic Management of Disease, Journal of Pharmacy and Pharmaceutical Sciences, vol.16, 2, 2013,pp 238-253
2015Cytochrome P450-Mediated Biotransformation of Sorafenib and Its N-Oxide Metabolite: Implications for Cell Viability and Human ToxicityGillani, Tina; Murray, Michael; Rawling, Tristan; Pharmacy; School of Medical Sciences: PharmacologyCytochrome P450-Mediated Biotransformation of Sorafenib and Its N-Oxide Metabolite: Implications for Cell Viability and Human Toxicity, Chemical Research in Toxicology, vol.28, 1, 2015,pp 92-102
2010Facile and Stereoselective Synthesis of (Z)-15-Octadecenoic Acid and (Z)-16-Nonadecenoic Acid: Monounsaturated Omega-3 Fatty AcidsCui, Pei (Sarah); Duke, Colin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; Pharmacy; PharmacyFacile and Stereoselective Synthesis of (Z)-15-Octadecenoic Acid and (Z)-16-Nonadecenoic Acid: Monounsaturated Omega-3 Fatty Acids, Lipids, vol.45, 2,pp 159-165
2014Lipid analogues as potential drugs for the regulation of mitochondrial cell deathAllison, Sarah; Dyari, Herryawan; Murray, Michael; Rawling, Tristan; Pharmacy; Northern Clinical School: Pharmacology; School of Medical Sciences: PharmacologyLipid analogues as potential drugs for the regulation of mitochondrial cell death, British Journal of Pharmacology, vol.171, 8, 2014,pp 2051-2066
2015Liquid chromatography-tandem mass spectrometry assay suitable for quantifying omega-3 epoxy-fatty acid analogs in mouse brain and plasmaMurray, Michael; Ching, Lai-Ming; Rawling, Tristan; Yung, Raymond; School of Medical Sciences: PharmacologyLiquid chromatography-tandem mass spectrometry assay suitable for quantifying omega-3 epoxy-fatty acid analogs in mouse brain and plasma, Journal of Liquid Chromatography and Related Technologies, vol.38, 8, 2015,pp 891-897
2017A Novel Arylurea Fatty Acid That Targets the Mitochondrion and Depletes Cardiolipin to Promote Killing of Breast Cancer CellsAllison, Sarah; Bourget, Kirsi; Chen, Yongjuan; Choucair, Hassan; Dunstan, Colin; Koolaji, Nooshin; Murray, Michael; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; Aerospace, Mechanical and Mechatronic Engineering; Pharmacy; School of Medical Sciences: PharmacologyA Novel Arylurea Fatty Acid That Targets the Mitochondrion and Depletes Cardiolipin to Promote Killing of Breast Cancer Cells, Journal of Medicinal Chemistry, vol.60, 20, 2017,pp 8661-8666
2017A novel synthetic analogue of v-3 17,18-epoxyeicosatetraenoic acid activates TNF receptor-1/ ASK1/JNK signaling to promote apoptosis in human breast cancer cellsAllison, Sarah; Bourget, Kirsi; Chen, Yongjuan; Dwyer, Julie; Eziwar Dyari, Herryawan Ryadi Bin; Murray, Michael; Sudarmana, W; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; MedicineA novel synthetic analogue of v-3 17,18-epoxyeicosatetraenoic acid activates TNF receptor-1/ ASK1/JNK signaling to promote apoptosis in human breast cancer cells, The FASEB Journal, vol.31, 12, 2017,pp 5246-5257
2012Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolitesCui, Pei (Sarah); Doddareddy, Munikumar; Ghassabian, Susan; Hibbs, David; Murray, Michael; Rawling, Tristan; Tattam, Bruce; Zhou, Fanfan; Edwards, Robert J.; Pharmacy; School of Medical Sciences: Brain & Mind Research Institute; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyRole of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites, Biochemical Pharmacology, vol.84, 2, 2012,pp 215-223
2014Selective Inhibition of Human Solute Carrier Transporters by Multikinase InhibitorsChan, Ting; Johnston, Rosie; Murray, Michael; Zhou, Fanfan; Rawling, Tristan; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; PharmacySelective Inhibition of Human Solute Carrier Transporters by Multikinase Inhibitors, Drug Metabolism and Disposition, vol.42, 11, 2014,pp 1851-1857
2017Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2Carland, Jane; Mostyn, Shannon; Ryan, Renae; Vandenberg, Robert; Rawling, Tristan; Shimmon, Susan; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologySynthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2, ACS Chemical Neuroscience, vol.8, 9, 2017,pp 1949-1959