Browsing by Author Pupo, Gulietta

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Issue DateTitleAuthor(s)Citation
2015Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanismsKefford, Richard (Rick); Long, Georgina; Menzies, Alexander Maxwel; Pupo, Gulietta; Rizos, Helen; Scolyer, Richard; Thompson, John; Becker, Jurgen C; Berking, Carola; Eroglu, Zeynep; et al, Various; Gogas, Helen; Gutzmer, R.; Johnson, Douglas B; Sucker, Antje; Ye, Fei; Zhao, Shilin; Zimmer, Lisa; Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: Pathology; Central Clinical School: SurgeryAcquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms, European Journal of Cancer, vol.51, 18, 2015,pp 2792-2799
2012Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK InhibitionBecker, Therese; Gowrishankar, Kavitha; Kefford, Richard (Rick); Pupo, Gulietta; Rizos, Helen; Snoyman, Stephanie; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteAcquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition, The Journal of Investigative Dermatology, vol.132, 7, 2012,pp 1850-1859
2006Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resourceBalleine, Rosemary; Butow, Phyllis; Clarke, Christine; Kirk, Judy; Leary, Jennifer; Mann, Graham; Pupo, Gulietta; Chenevix-Trench, Georgia; Edkins, Edward; Evans, Gerda M.; Fereday, Sian; Gattas, Michael; Giles, Graham; Goldblatt, Jack; Haan, Eric; Hopper, John; Lindeman, Geoffrey J; Niedermayr, Eveline; Phillips, Kelly-Anne; Picken, Sandra; Saunders, Christobel; Scott, Clare L; Spurdle, Amanda B.; Suthers, Graeme; The Kathleen Cuningham Consortium for Research in Familial Breast Cancer, kConFab; Thorne, Heather; Tucker, Katherine M.; Western Clinical School: Medicine (Westmead); Psychology; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource, Breast Cancer Research, vol.8,(1),2006,pp N/A-N/A
2013Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in MelanomaBecker, Therese; Carlino, Matteo; Gowrishankar, Kavitha; Kefford, Richard (Rick); Long, Georgina; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Snoyman, Stephanie; Saunders, Catherine; Zhang, Xu Dong; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteAntiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma, Molecular Cancer Therapeutics, vol.12, 7, 2013,pp 1332-1342
2007BCoR-L1 variation and breast cancerMann, Graham; Pupo, Gulietta; Arnold, Jeremy; Brown, Carolyn J.; Chenevix-Trench, Georgia; Khanna, Kum Kum; Lose, Felicity; Spurdle, Amanda B.; Young, David B; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)BCoR-L1 variation and breast cancer, Breast Cancer Research, vol.9,(4),2007,pp 1-12
2014BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impactBecker, Therese; Boyd, Suzanah; Carlino, Matteo; Fung, Carina; Haydu, Lauren; Howle, Julie; Kefford, Richard (Rick); Long, Georgina; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Scolyer, Richard; Thompson, John; Hyman, Jessica; Menzies, Alexander; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Infectious Diseases; Central Clinical School: Surgery; Western Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: SurgeryBRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact, Clinical Cancer Research, vol.20, 7, 2014,pp 1965-1977
2013BRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III MelanomaCampain, Anna; Carter, Candace; De Silva, Chitra; Gerega, Sebastien; Hersey, Peter; Kefford, Richard (Rick); Lai, Kenneth; Mann, Graham; Pianova, Svetlana; Pupo, Gulietta; Schramm, Sarah-Jane; Scolyer, Richard; Synnott, Catherine; Thompson, John; Wilmott, James; Yang, Yee (Jean); Mathematics & Statistics; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Melanoma Foundation; Biological Sciences; Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Clinical Ophthal & Eye Health; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Central Clinical School: Pathology; RADS - Research Analytics & Data Strategy; Central Clinical School: Surgery; Central Clinical School: Surgery; Mathematics & StatisticsBRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III Melanoma, The Journal of Investigative Dermatology, vol.133, 2, 2013,pp 509-517
2017Clinical significance of intronic variants in BRAF inhibitor resistant melanomas with altered BRAF transcript splicingCarlino, Matteo; Kefford, Richard (Rick); Long, Georgina; Menzies, Alexander Maxwel; Pedersen, Bernadette; Pupo, Gulietta; Rizos, Helen; Scolyer, Richard; Boyd, Suzanah C; Fung, Carina; Hayward, Nicholas K; Johansson, Peter; Westmead Clinical School: Medicine; Westmead Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Westmead Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Central Clinical School: PathologyClinical significance of intronic variants in BRAF inhibitor resistant melanomas with altered BRAF transcript splicing, Biomarker Research, vol.5, 17, 2017,pp 1-4
2016Comparison of whole-exome sequencing of matched fresh and formalin fixed paraffin embedded melanoma tumours: implications for clinical decision makingKakavand, Hojabr; Long, Georgina; Mann, Graham; Menzies, Alexander Maxwel; Pupo, Gulietta; Scolyer, Richard; Wilmott, James; De Paoli-Iseppi, Ricardo; Dias, Kerith-Rae; Dinger, Marcel; Hayward, Nicholas K; Johansson, Peter; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Central Clinical School: Pathology; Central Clinical School: SurgeryComparison of whole-exome sequencing of matched fresh and formalin fixed paraffin embedded melanoma tumours: implications for clinical decision making, Pathology, vol.48, 3, 2016,pp 261-266
2014Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; James, Wilmott; McArthur, Grant A.; Tummino, Peter J; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteControl of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151, Pigment Cell & Melanoma Research, vol.27, 6, 2014,pp 1126-1137
2014Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanomaCarlino, Matteo; Fung, C.; Gowrishankar, Kavitha; Hersey, Peter; Kefford, Richard (Rick); Long, Georgina; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Snoyman, Stephanie; Todd, Jason; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteDifferential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma, Molecular Oncology, vol.8, 3, 2014,pp 544-554
2002Dominant Negative ATM Mutations in Breast Cancer FamiliesKirk, Judy; Mann, Graham; Pupo, Gulietta; Tucker, Peter; Bendix, Regina; Chen, Xiaoshuang; Chenevix-Trench, Georgia; Cummings, M; Donn, Karen; Dork, Thilo; et, al; Gatei, Magtouf; Jenkins, Mark; Kelly, Helena; Marsh, Anna; Nyholt, Dale; Scott, Clare; Spurdle, Amanda B.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Psychological MedicineDominant Negative ATM Mutations in Breast Cancer Families, Journal of the National Cancer Institute, vol.94,(3),2002,pp 205-215
2014The Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma CellsGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteThe Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma Cells, Journal of Investigative Dermatology, vol.134, 11, 2014,pp 1523-1747
2010Familial Concordance of Breast Cancer Pathology as an Indicator of Genotype in Multiple-Case FamiliesBalleine, Rosemary; Bilous, Michael; Byth Wilson, Karen; Mann, Graham; Pathmanathan, Nirmala; Provan, Pamela; Pupo, Gulietta; Cummings, Margaret; Farshid, Gelareh; kConFab Investigators, .; Salisbury, Elizabeth; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); School of Public Health: NH&MRC Clinical Trials Centre; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Familial Concordance of Breast Cancer Pathology as an Indicator of Genotype in Multiple-Case Families, Genes Chromosomes and Cancer, vol.49, 12,pp 1082-1094
2006A genome wide linkage search for breast cancer susceptibility genes.Mann, Graham; Pupo, Gulietta; Chenevix-Trench, Georgia; Easton, Douglas F.; et, al; Lynch, Henry; McGuffog, Lesley; Newman, B.; Odefrey, Fabrice; Renard, Helene; Southey, Melissa C.; Szabo, Csilla; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)A genome wide linkage search for breast cancer susceptibility genes., Genes Chromosomes & Cancer, vol.45,(7),2006,pp 646-655
2012A high-throughput panel for identifying clinically relevant mutation profiles in melanomaCarter, Candace; Mann, Graham; Pupo, Gulietta; Scolyer, Richard; Tembe, Varsha; Aoude, Lauren G; Dutton-Regester, Ken; et al, various; Hunt, Priscilla; Irwin, Darryl; Lanagan, Cathy; O'Connor, Linda; O'Rourke, Michael; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Central Clinical School: Pathology; Western Clinical School: Medicine (Westmead)A high-throughput panel for identifying clinically relevant mutation profiles in melanoma, Molecular Cancer Therapeutics, vol.11, 4, 2012,pp 888-897
2012Identification of TFG (TRK-Fused Gene) as a Putative Metastatic Melanoma Tumor Suppressor GeneMann, Graham; Pupo, Gulietta; Scolyer, Richard; Tembe, Varsha; Aoude, Lauren G; Carter, Candace; Dutton-Regester, Ken; et al, various; Lanagan, Cathy; Nancarrow, Derek J.; O'Connor, Linda; O'Rourke, Michael; Stark, Mitchell; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Central Clinical School: Pathology; Western Clinical School: Medicine (Westmead)Identification of TFG (TRK-Fused Gene) as a Putative Metastatic Melanoma Tumor Suppressor Gene, Genes Chromosomes and Cancer, vol.51, 5, 2012,pp 452-461
2010IGFBP7 is not required for B-RAF-induced melanocyte senescenceBecker, Therese; Haferkamp, Sebastian; Irvine, Malama; Kefford, Richard (Rick); Mann, Graham; Pupo, Gulietta; Rizos, Helen; Scolyer, Richard; Scurr, Lyndee; Becker, Jurgen; Lai, Ken; Schrama, David; Western Clinical School: Westmead Millennium Institute; Western Clinical School (Westmead): Office; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Pathology; Western Clinical School: Medicine (Westmead)IGFBP7 is not required for B-RAF-induced melanocyte senescence, Cell, vol.141, 4,pp 717-727
2014Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanomaCarlino, Matteo; Fung, Carina; Howle, Julie; Kefford, Richard (Rick); Long, Georgina; Menzies, Alexander Maxwel; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Scolyer, Richard; Shahheydari, Hamideh; Tembe, Varsha; Thompson, John; Hayward, Nicholas K; Hyman, Jessica; Johansson, Peter; Western Clinical School: Medicine (Westmead); Infectious Diseases; Western Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Central Clinical School: Pathology; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Central Clinical School: SurgeryIncreased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma, Nature Communications, vol.5, N/A, 2014,pp 1-9
2014Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanomaLong, Georgina; Pupo, Gulietta; Scolyer, Richard; Chen, Guo; Cooper, Zachary; Deng, Wanleng; et al, Various; Frederick, Dennie; Gopal, Vashisht; Komurov, Kakajan; Patel, Lalit; Rizos, Helen; Sehgal, Vasudha; Zhang, Jiexin; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Medicine (Westmead); Central Clinical School: PathologyInhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma, Cancer Research, vol.74, 23, 2014,pp 7037-7047