Browsing by Author Pickett, Hilda

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Issue DateTitleAuthor(s)Citation
2009Alternative lengthening of telomeres in human cellsPickett, Hilda; Reddel, Roger; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAlternative lengthening of telomeres in human cells in Telomeres and Telomerase in Cancer, Springer, 2009, pp. 127-148
2013Alternative lengthening of telomeres in normal mammalian somatic cellsNeumann, Axel; Pickett, Hilda; Reddel, Roger; Tam, Patrick; Watson, Catherine; Noble, Jane R; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAlternative lengthening of telomeres in normal mammalian somatic cells, Genes and Devleopment, vol.27, 1, 2013,pp 18-23
2017Alternative Lengthening of Telomeres: DNA Repair Pathways ConvergePickett, Hilda; Sobinoff, Alexander; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)Alternative Lengthening of Telomeres: DNA Repair Pathways Converge, Trends in Genetics, vol.33, 12, 2017,pp 921-932
2013Alternative lengthening of telomeres: remodeling the telomere architectureConomos, Dimitri; Pickett, Hilda; Reddel, Roger; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAlternative lengthening of telomeres: remodeling the telomere architecture, Frontiers in Oncology, vol.3, N/A, 2013,pp 1-7
2008Amplification of Telomerase Reverse Transcriptase Gene in Human Mammary Epithelial Cells with Limiting Telomerase RNA Expression LevelsBryan, Tracy; Cao, Ying; Chang, Andy; Huschtscha, Lily; Neumann, Axel; Nouwens, Amanda; Pickett, Hilda; Reddel, Roger; Toouli, Christian; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Concord Clinical School: Age & Alzh Dis Rrch Educ; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAmplification of Telomerase Reverse Transcriptase Gene in Human Mammary Epithelial Cells with Limiting Telomerase RNA Expression Levels, Cancer Research, vol.68, 9, 2008,pp 3115-3123
2017Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrityPickett, Hilda; Chan, F Lyn; Daly, Roger; Hii, Linda; Huang, Cheng; Lin, Jane I; Novy, Karel; Nunez-Iglesias, Juan; Schittenhelm, Ralf B; Udugama, Maheshi; Vinod, Benjamin; Wong, Lee H; Childrens Medical Research Institute (CMRI)Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity, Nucleic Acids Research, vol.45, 21, 2017,pp 12340-12353
2017BLM and SLX4 play opposing roles in recombination-dependent replication at human telomeresAllen, Joshua; Neumann, Axel; Pickett, Hilda; Reddel, Roger; Sobinoff, Alexander; Walsh, Monica; Yang, Sile; Henson, Jeremy; Childrens Medical Research Institute (CMRI); Children's Hospital Westmead: Childrens Medical Research Ins; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Children's Hospital Westmead: Childrens Medical Research InsBLM and SLX4 play opposing roles in recombination-dependent replication at human telomeres, EMBO Journal, vol.36, 19, 2017,pp 2907-2919
2015A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of TelomeraseBryan, Tracy; Killedar, Anagha; Pickett, Hilda; Reddel, Roger; Sobinoff, Alexander; Stutz, Michael D.; Tomlinson, Christopher; Beesley, Jonathan; Chenevix-Trench, Georgia; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Medicine; Central Clinical School: Medicine; Children's Hospital Westmead: Childrens Medical Research InsA Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase, PLoS Genetics, vol.11, 6, 2015,pp 1-23
2017Comparative analysis of whole genome sequencing-based telomere length measurement techniquesArthur, Jonathan; Lee, Michael; Napier, Christine; Pickett, Hilda; Reddel, Roger; Yang, Fiona; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)Comparative analysis of whole genome sequencing-based telomere length measurement techniques, Methods, vol.114, N/A, 2017,pp 4-15
2009Control of telomere length by a trimming mechanism that involves generation of t-circlesCesare, Anthony; Neumann, A; Pickett, Hilda; Reddel, Roger; Johnston, Rebecca; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsControl of telomere length by a trimming mechanism that involves generation of t-circles, The EMBO Journal, vol.28,(7),2009,pp 799-809
2009DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activityAu, Amy; Cao, Ying; Chang, Andy; Henson, J; Huschtscha-Holliday, Lily; Pickett, Hilda; Reddel, Roger; Northern Clinical School: Kolling Institute; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsDNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity, Nature Biotechnology, vol.27, 12,pp 1181-1185
2017Extensive Proliferation of Human Cancer Cells with Ever-Shorter TelomeresArthur, Jonathan; Dagg, Rebecca; Lau, Loretta; Napier, Christine; Neumann, Axel; Pickett, Hilda; Reddel, Roger; Sobinoff, Alexander; Teber, Erdahl; Haber, M; Henson, J; Murray, J; Reynolds, C; Childrens Medical Research Institute (CMRI); School of Molecular Bioscience (SMB); Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Medical Research Institute (CMRI); Children's Hospital Westmead: Childrens Medical Research Ins; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres, Cell Reports, vol.19, 12, 2017,pp 2544-2556
2012Extreme telomere length dimorphism in the Tasmanian devil and related marsupials suggests parental control of telomere lengthNeumann, Axel; Pickett, Hilda; Reddel, Roger; Bender, Hannah; Conlan, Carly; Deakin, Janine E.; Graves, Jennifer A. Marshall; Greider, Carol; Hannon, Gregory; McMillan, Daniel; Murchison, Elizabeth; Strong, Margaret; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsExtreme telomere length dimorphism in the Tasmanian devil and related marsupials suggests parental control of telomere length, PLoS One, vol.7, 9, 2012,pp 1-10
2014Folate Deficiency Induces Dysfunctional Long and Short Telomeres; Both States are Associated With Hypomethylation and DNA Damage in Human WIL2-NS CellsPickett, Hilda; Au, Amy Y.M.; Bull, C.M.; Fenech, Michael F; Hande, M Prakash; Low, Grace Kah Mun; Mayrhofer, Graham; O'Callaghan, Nathan J; Zeegers, Dimphy; Children's Hospital Westmead: Childrens Medical Research InsFolate Deficiency Induces Dysfunctional Long and Short Telomeres; Both States are Associated With Hypomethylation and DNA Damage in Human WIL2-NS Cells, Cancer Prevention Research, vol.7, 1, 2014,pp 128-138
2011Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancersPickett, Hilda; Reddel, Roger; Stutz, Michael D.; Beesley, Johnathan; Chen, Xiaoqing; Dunning, Alison; et al, various; Johnatty, Sharon E.; Li, Jun; Lu, Yi; Michailidou, Kyriaki; Palmieri, Rachel T.; Rider, David; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Central Clinical School: MedicineFunctional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers, PLoS One, vol.6, 9, 2011,pp 1-6
2015Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeresPickett, Hilda; Chan, F Lyn; Chang, Fiona T M; Collas, Philippe; Mann, Jeffrey R; Mayne, Lynne; McGhie, James D R; Tang, Michelle C; Udugama, Maheshi; Wong, Lee H; Childrens Medical Research Institute (CMRI)Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres, Nucleic Acids Research, vol.43, 21, 2015,pp 10227-10237
2014Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1Al-Odaib, Ahmad; Barbaro, Pasquale; Bryan, Tracy; Christodoulou, John; Kartawinata, Melissa; Pickett, Hilda; Reddel, Roger; Chen, Yulan; Guo, Yiran; Hakonarson, Haron; Keating, Brendan; Kilo, Tatjana; Li, Jiankang; Teo, Juliana; Tian, Lifeng; Xu, Xun; Childrens Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Childrens Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsInherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1, Blood, vol.124, 18, 2014,pp 2767-2774
2015Molecular mechanisms of activity and derepression of alternative lengthening of telomeresPickett, Hilda; Reddel, Roger; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)Molecular mechanisms of activity and derepression of alternative lengthening of telomeres, Nature Structural and Molecular Biology, vol.22, 11, 2015,pp 875-880
2013Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerPickett, Hilda; Reddel, Roger; Stutz, Michael D.; Beesley, Johnathan; Bojesen, Stig; Edwards, Stacey; et al, Various; Johnatty, Sharon E.; Michailidou, Kyriaki; Pooley, Karen; Shen, Howard; Smart, Chanel; Tyrer, Johnathan; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Central Clinical School: MedicineMultiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer, Nature Genetics, vol.45, 4, 2013,pp 371-384
2016MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of DyskerinPickett, Hilda; et al, Various; Kong, Cheng Fei; Liu, Bing; Maritz, Michelle F; Murray, Jayne; O'Brien, Rosemary; Purgato, Stefania; Russell, Amanda; Tran, Sieu L; Yang, Chen; Childrens Medical Research Institute (CMRI)MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin, Cancer Research, vol.76, 12, 2016,pp 3604-3617