Browsing by Author Patel, Brijeshkumar

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Issue DateTitleAuthor(s)Citation
2017Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effectAmmit, Alaina; Baehring, Gina; Kugel, Michael; Patel, Brijeshkumar; Central Clinical School: Woolcock Inst. of Medical Research; Central Clinical School: Woolcock Inst. of Medical Research; Central Clinical School: Woolcock Inst. of Medical Research; PharmacyDoxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect, Pulmonary Pharmacology & Therapeutics, vol.45, N/A, 2017,pp 34-39
2016IL-17A increases TNF-(alpha)-induced COX-2 protein stability and augments PGE2 secretion from airway smooth muscle cells: impact on (beta)2 -adrenergic receptor desensitizationAmmit, Alaina; Gelissen, Ingrid Catherina; Oliver, Brian; Patel, Brijeshkumar; Prabhala, Pavan; Rumzhum, Nowshin; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; PharmacyIL-17A increases TNF-(alpha)-induced COX-2 protein stability and augments PGE2 secretion from airway smooth muscle cells: impact on (beta)2 -adrenergic receptor desensitization, Allergy, vol.71, 3, 2016,pp 387-396
2015Inhibitors of PDE4, but Not PDE3, Increase β2-agonist-induced Expression of Anti-inflammatory MKP-1 in Airway Smooth Muscle CellsAmmit, Alaina; Oliver, Brian; Patel, Brijeshkumar; Prabhala, Pavan; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; PharmacyInhibitors of PDE4, but Not PDE3, Increase β2-agonist-induced Expression of Anti-inflammatory MKP-1 in Airway Smooth Muscle Cells, American Journal of Respiratory Cell and Molecular Biology, vol.52, 5, 2015,pp 634-640
2013Long-acting beta2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (mkp-1) in airway smooth muscle cellsAlkhouri, Hatem; Ammit, Alaina; Ge, Qi; Manetsch, Melanie; Patel, Brijeshkumar; Rahman, Mohammad Mostafizur; Ramsay, Emma; Rumzhum, Nowshin; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyLong-acting beta2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (mkp-1) in airway smooth muscle cells, PLoS One, vol.8, 3, 2013,pp 1-9
2016The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cellsAmmit, Alaina; Gelissen, Ingrid Catherina; Lebender, Leonard; Patel, Brijeshkumar; Prunte, Laura; Rahman, Mohammad Mostafizur; Clark, Andrew R; Hansbro, Philip M.; Morris, Jonathan C.; Verrills, Nicole M.; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyThe phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells, Scientific Reports, vol.6, N/A, 2016,pp 1-8
2016The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cellsAmmit, Alaina; Gelissen, Ingrid Catherina; Lebender, Leonard; Patel, Brijeshkumar; Prunte, Laura; Rahman, Mohammad Mostafizur; Clark, Andrew R; Hansbro, Philip M.; Morris, Jonathan C.; Verrills, Nicole M.; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyThe phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells, Scientific Reports, vol.6, N/A, 2016,pp 1-8
2015Repression of breast cancer cell growth by proteasome inhibitors in vitro: impact of mitogen-activated protein kinase phosphatase 1Ammit, Alaina; Che, Wenchi; Co, Wai; Donat, Claudia; Martin, Janet; Patel, Brijeshkumar; Prabhala, Pavan; Schulz, Vera; Schuster, Friederike; Wang, Mary; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Northern Clinical School: Kolling Institute; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyRepression of breast cancer cell growth by proteasome inhibitors in vitro: impact of mitogen-activated protein kinase phosphatase 1, Cancer Biology & Therapy, vol.16, 5, 2015,pp 780-789
2017Roflumilast N-oxide in combination with formoterol enhances the antiinflammatory effect of dexamethasone in airway smooth muscle cellsAmmit, Alaina; Baehring, Gina; Oliver, Brian; Patel, Brijeshkumar; Rahman, Mohammad Mostafizur; Tang, Francesca; Xenaki, Dikaia; Central Clinical School: Woolcock Inst. of Medical Research; Central Clinical School: Woolcock Inst. of Medical Research; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Central Clinical School: Woolcock Inst. of Medical ResearchRoflumilast N-oxide in combination with formoterol enhances the antiinflammatory effect of dexamethasone in airway smooth muscle cells, American Journal of Respiratory Cell and Molecular Biology, vol.56, 4, 2017,pp 532-538
2012Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cellsAmmit, Alaina; Che, W; Ge, Qi; Manetsch, Melanie; Patel, Brijeshkumar; Quante, Timo; Rahman, MD Mahfuzur; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; PharmacySphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cells, Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol.1823, N/A, 2012,pp 1658-1665
2016Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition: Novel Role as a Protein Phosphatase 2A ActivatorAmmit, Alaina; Oliver, Brian; Patel, Brijeshkumar; Rahman, Mohammad Mostafizur; Rumzhum, Nowshin; Verrills, Nicole M.; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; PharmacyTheophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition: Novel Role as a Protein Phosphatase 2A Activator, American Journal of Respiratory Cell and Molecular Biology, vol.54, 6, 2016,pp 792-801
2016Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition: Novel Role as a Protein Phosphatase 2A ActivatorAmmit, Alaina; Oliver, Brian; Patel, Brijeshkumar; Rahman, Mohammad Mostafizur; Rumzhum, Nowshin; Verrills, Nicole M.; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; PharmacyTheophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition: Novel Role as a Protein Phosphatase 2A Activator, American Journal of Respiratory Cell and Molecular Biology, vol.54, 6, 2016,pp 792-801
2016TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activatorsAmmit, Alaina; Patel, Brijeshkumar; Prabhala, Pavan; Rahman, Mohammad Mostafizur; Rumzhum, Nowshin; Wickop, Thomas; Hansbro, Philip M.; Verrills, Nicole M.; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyTLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators, The International Journal of Biochemistry and Cell Biology, vol.78, N/A, 2016,pp 279-287