Browsing by Author Panchapakesan, Usha

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Issue DateTitleAuthor(s)Citation
2011Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-B1Chen, Xin-Ming; Panchapakesan, Usha; Pollock, Carol; Qi, Weier; Wong, Muh; Silva, Diego G.; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: MedicineCation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-B1, American Journal of Physiology: Renal Physiology, vol.301, 1, 2011,pp F84-F93
2015The dipeptidyl peptidase-4 inhibitor linagliptin preserves endothelial function in mesenteric arteries from type 1 diabetic rats without decreasing plasma glucosePanchapakesan, Usha; Pollock, Carol; Salheen, S M; Woodman, O L; Northern Clinical School: Medicine; Northern Clinical School: MedicineThe dipeptidyl peptidase-4 inhibitor linagliptin preserves endothelial function in mesenteric arteries from type 1 diabetic rats without decreasing plasma glucose, PloS One, vol.10, 11, 2015,pp 1-15
2015The DPP-4 inhibitor linagliptin and the GLP-1 receptor agonist exendin-4 improve endothelium-dependent relaxation of rat mesenteric arteries in the presence of high glucosePanchapakesan, Usha; Pollock, Carol; Salheen, S M; Woodman, O L; Northern Clinical School: Medicine; Northern Clinical School: MedicineThe DPP-4 inhibitor linagliptin and the GLP-1 receptor agonist exendin-4 improve endothelium-dependent relaxation of rat mesenteric arteries in the presence of high glucose, Pharmacological Research, vol.94, N/A, 2015,pp 26-33
2004The Effect Of High Glucose And Ppar-Gamma Agonists On Ppar-Gamma Expression And Function In Hk-2 Cells.Chen, Xin-Ming; Panchapakesan, Usha; Pollock, Carol; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: MedicineThe Effect Of High Glucose And Ppar-Gamma Agonists On Ppar-Gamma Expression And Function In Hk-2 Cells., American Journal of Physiology: Renal Physiology, vol.287,(3),2004,pp F528-F534
2013Effects of SGLT2 inhibition in human kidney proximal tubular cells - renoprotection in diabetic nephropathy?Gangadharan Komala, Muralikris; Gross, Simon; Mather, Amanda; Mudaliar, Harshini; Panchapakesan, Usha; Pegg, Kate; Pollock, Carol; Forbes, Josephine; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Clinical Schools; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: MedicineEffects of SGLT2 inhibition in human kidney proximal tubular cells - renoprotection in diabetic nephropathy?, PLoS One, vol.8, 2, 2013,pp 1-8
2010HMGB1 Contributes to Kidney Ischemia Reperfusion InjuryChadban, Steven; Corpuz, Theresa; Ma, Jin; Panchapakesan, Usha; Wang, Peng; Wu, Huiling; Wyburn, Kate; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: MedicineHMGB1 Contributes to Kidney Ischemia Reperfusion Injury, Journal of the American Society of Nephrology, vol.21, 11,pp 1878-1890
2009The importance of the kidney proximal tubular cells in thiazolidinedione mediated sodium and water uptakePanchapakesan, Usha; Pollock, Carol; Saad, Sonia; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: MedicineThe importance of the kidney proximal tubular cells in thiazolidinedione mediated sodium and water uptake, Nephrology, vol.14,(3),2009,pp 298-301
2014Inhibition of Kidney Proximal Tubular Glucose Reabsorption Does Not Prevent against Diabetic Nephropathy in Type 1 Diabetic eNOS Knockout MiceGangadharan Komala, Muralikrishna; Gross, Simon; Huang, Chunling; Mather, Amanda; Mudaliar, Harshini; Panchapakesan, Usha; Pegg, Kate; Pollock, Carol; Shen, Sylvie; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Clinical Schools; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: MedicineInhibition of Kidney Proximal Tubular Glucose Reabsorption Does Not Prevent against Diabetic Nephropathy in Type 1 Diabetic eNOS Knockout Mice, PloS One, vol.9, 11, 2014,pp 1-12
2015Linagliptin Limits High Glucose Induced Conversion of Latent to Active TGFß through Interaction with CIM6PR and Limits Renal Tubulointerstitial Fibronectin.Gangadharan Komala, Muralikrishna; Gross, Simon; Panchapakesan, Usha; Pollock, Carol; Zaky, Amgad; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteLinagliptin Limits High Glucose Induced Conversion of Latent to Active TGFß through Interaction with CIM6PR and Limits Renal Tubulointerstitial Fibronectin., PloS One, vol.10, 10, 2015,pp e0141143-N/A
2016Long non-coding RNAs-towards precision medicine in diabetic kidney disease?Panchapakesan, Usha; Pollock, Carol; Northern Clinical School: Medicine; Northern Clinical School: MedicineLong non-coding RNAs-towards precision medicine in diabetic kidney disease?, Clinical Science, vol.130, 18, 2016,pp 1599-1602
2007Nanomedicines in the treatment of anemia in renal disease: focus on CERA (Continuous Erythropoietin Receptor Activator)Panchapakesan, Usha; Pollock, Carol; Sumual, Siska; Northern Clinical School: Medicine; Northern Clinical School: Medicine; MedicineNanomedicines in the treatment of anemia in renal disease: focus on CERA (Continuous Erythropoietin Receptor Activator), International Journal of Nanomedicine (Print), vol.2,(1),2007,pp 33-38
2012Novel Treatments in Diabetic NephropathyPanchapakesan, Usha; Pollock, Carol; Northern Clinical School: Medicine; Northern Clinical School: MedicineNovel Treatments in Diabetic Nephropathy, Current Hypertension Reviews, vol.8, 1, 2012,pp 71-78
2016Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db micePanchapakesan, Usha; Pollock, Carol; Borg, Danielle J; Flemming, Nicole B; Forbes, Josephine; Fotheringham, Amelia K; Gallo, Linda A; Harvie, Ben M; Kinneally, Toni L; Koepsell, Hermann; McCarthy, Domenica; Vallon, Volker; Ward, Micheal S; Yeh, Shang-Ming; Zhuang, Aowen; Northern Clinical School: Medicine; Northern Clinical School: MedicineOnce daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice, Scientific Reports, vol.6, N/A, 2016,pp 1-16
2005PPAR gamma agonists exert antifibrotic effects in renal tubular cells exposed to high glucose.Chen, Xin-Ming; Panchapakesan, Usha; Pollock, Carol; Sumual, Siska; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstitutePPAR gamma agonists exert antifibrotic effects in renal tubular cells exposed to high glucose., American Journal of Physiology: Renal Physiology, vol.289,(5),2005,pp F1153-F1158
2014Requirement for TLR2 in the development of albuminuria, inflammation and fibrosis in experimental diabetic nephropathyChadban, Steven; Ma, Jin; Panchapakesan, Usha; Pollock, Carol; Wu, Huiling; Zhao, Cathy Yunjia; Central Clinical School: Medicine; School of Medical Sciences: Bosch Institute; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Medicine; Concord Clinical School: MedicineRequirement for TLR2 in the development of albuminuria, inflammation and fibrosis in experimental diabetic nephropathy, International Journal of Clinical and Experimental Pathology, vol.7, 2, 2014,pp 481-495
2015The role of dipeptidyl peptidase – 4 inhibitors in diabetic kidney diseasePanchapakesan, Usha; Pollock, Carol; Northern Clinical School: Medicine; Northern Clinical School: MedicineThe role of dipeptidyl peptidase – 4 inhibitors in diabetic kidney disease, Frontiers in Immunology, vol.6, N/A, 2015,pp 1-5
2014The Role of TLR2 and 4-Mediated Inflammatory Pathways in Endothelial Cells Exposed to High GlucoseChadban, Steven; Ma, Jin; Mudaliar, Harshini; Panchapakesan, Usha; Pollock, Carol; Wu, Huiling; Central Clinical School: Medicine; School of Medical Sciences: Bosch Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: MedicineThe Role of TLR2 and 4-Mediated Inflammatory Pathways in Endothelial Cells Exposed to High Glucose, PLoS One, vol.9, 10, 2014,pp e108844-N/A
2014Role of toll-like receptors in diabetic nephropathyMudaliar, Harshini; Panchapakesan, Usha; Pollock, Carol; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: MedicineRole of toll-like receptors in diabetic nephropathy, Clinical Science, vol.126, 10, 2014,pp 685-694
2016Saxagliptin reduces renal tubulointerstitial inflammation, hypertrophy and fibrosis in diabetesGangadharan Komala, Muralikrishna; Gross, Simon; Panchapakesan, Usha; Pollock, Carol; Zaky, Amgad A; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteSaxagliptin reduces renal tubulointerstitial inflammation, hypertrophy and fibrosis in diabetes, Nephrology, vol.21, 5, 2016,pp 423-431
2016Saxagliptin reduces renal tubulointerstitial inflammation, hypertrophy and fibrosis in diabetesGangadharan Komala, Muralikrishna; Gross, Simon; Panchapakesan, Usha; Pollock, Carol; Zaky, Amgad A; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteSaxagliptin reduces renal tubulointerstitial inflammation, hypertrophy and fibrosis in diabetes, Nephrology, vol.21, 5, 2016,pp 423-431