Browsing by Author O'Toole, Sandra

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Issue DateTitleAuthor(s)Citation
2014Alterations of insulin-like growth factor-1 receptor gene copy number and protein expression are common in non-small cell lung cancerCooper, Wendy Anne; O'Toole, Sandra; Yu, Bing; Kennedy, Catherine; Kohonen-Corish, Maija R.J.; McCaughan, Brian; Ng, Chiu Chin; Selinger, Christina; Tran, Thang N.; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: MedicineAlterations of insulin-like growth factor-1 receptor gene copy number and protein expression are common in non-small cell lung cancer, Journal of Clinical Pathology, vol.67, 11, 2014,pp 985-991
2016Alterations of MET Gene Copy Number and Protein Expression in Primary Non-Small-Cell Lung Cancer and Corresponding Nodal MetastasesCooper, Wendy Anne; O'Toole, Sandra; Kennedy, Catherine; Kohonen-Corish, Maija R.J.; McCaughan, Brian; Selinger, Christina; Tran, Thang N.; Central Clinical School: Medicine; Central Clinical School: PathologyAlterations of MET Gene Copy Number and Protein Expression in Primary Non-Small-Cell Lung Cancer and Corresponding Nodal Metastases, Clinical Lung Cancer, vol.17, 1, 2016,pp 30-38
2017The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinomaO'Toole, Sandra; Connelly, A; Coulson, Rhiannon; Deb, Siddhartha; et al, Various; Kumar, Beena; Liew, S; Parslow, A; Poh, Ashleigh; Vargas, A. Cristina; Yee, N; Central Clinical School: PathologyThe angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma, Oncotarget, vol.8, 12, 2017,pp 18640-18656
2016Atypical Ewing sarcoma breakpoint region 1 fluorescence in-situ hybridization signal patterns in bone and soft tissue tumours: diagnostic experience with 135 casesBhadri, Vivek; Cooper, Wendy Anne; Gupta, Ritu; Karim, Rooshdiya; McCarthy, Stanley; O'Toole, Sandra; Scolyer, Richard; Tattersall, Martin; Bonar, S. Fiona; Boyle, Richard; Brown, Wendy; Maclean, Fiona; Mahar, Annabelle; Satgunaseelan, Laveniya; Schatz, Julie; Selinger, Christina; Soper, Judy; Stalley, Paul; Thomas, David; Vargas, A. Cristina; Central Clinical School: Medicine; Central Clinical School: Medicine; School of Medical Sciences: Physiology; Central Clinical School: Pathology; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Pathology; Central Clinical School: MedicineAtypical Ewing sarcoma breakpoint region 1 fluorescence in-situ hybridization signal patterns in bone and soft tissue tumours: diagnostic experience with 135 cases, Histopathology, vol.69, 6, 2016,pp 1000-1011
2013B-Catenin Signaling is a Critical Event in ErbB2-Mediated Mammary Tumor ProgressionO'Toole, Sandra; Sutherland, Robert L.; Bui, Tung; Deblois, Genevieve; Giguere, Vincent; Hallett, Michael; Kahn, Michael; Lesurf, Robert; Lopez-Knowles, Elena; Millar, E. K. A.; Muller, William J.; Sanguin-Gendreau, Virginie; Schade, Babette; Zardawi, Sarah J; Central Clinical School: Pathology; Central Clinical School: PathologyB-Catenin Signaling is a Critical Event in ErbB2-Mediated Mammary Tumor Progression, Cancer Research, vol.73, 14, 2013,pp 4474-4487
2009BAG-1 predicts patient outcome and tamoxifen responsiveness in ER-positive invasive ductal carcinoma of the breastMcNeil, Catriona; O'Toole, Sandra; Anderson, Luke R.; Biankin, Andrew V.; Butt, Alison Joy; Crea, P; Henshall, Susan M.; Millar, E.; Morey, Adrienne; Musgrove, Elizabeth A.; Pinese, Mark; Sutherland, Robert L.; Western Clinical School: Medicine (Westmead); Central Clinical School: PathologyBAG-1 predicts patient outcome and tamoxifen responsiveness in ER-positive invasive ductal carcinoma of the breast, British Journal of Cancer, vol.100, 1,pp 123-133
2013BRAF inhibitor activity in V600R metastatic melanomaClements, Arthur; Kefford, Richard (Rick); Long, Georgina; O'Toole, Sandra; Klein, Oliver; Menzies, Alexander; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: PathologyBRAF inhibitor activity in V600R metastatic melanoma, European Journal of Cancer, vol.49, 5, 2013,pp 1073-1079
2015BRAF mutations in non-small cell lung cancerCooper, Wendy Anne; O'Toole, Sandra; Yu, Bing; Kao, Steven; Luk, Peter; Lum, Trina; Mercorella, B; Ng, Chiu Chin; Selinger, Christina; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: MedicineBRAF mutations in non-small cell lung cancer, Translational Lung Cancer Research, vol.4, 2, 2015,pp 142-148
2016BRAF(V600E) and NRAS(Q61L/Q61R) mutation analysis in metastatic melanoma using immunohistochemistry: a study of 754 cases highlighting potential pitfalls and guidelines for interpretation and reportingCooper, Wendy Anne; Kakavand, Hojabr; Long, Georgina; O'Toole, Sandra; Saw, Robyn; Scolyer, Richard; Smith, Elisabeth; Walker, Emily; Wilmott, James; Yu, Bing; Lum, Trina; Selinger, Christina; Central Clinical School: Medicine; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Medicine; Medicine; Central Clinical School: Surgery; Central Clinical School: MedicineBRAF(V600E) and NRAS(Q61L/Q61R) mutation analysis in metastatic melanoma using immunohistochemistry: a study of 754 cases highlighting potential pitfalls and guidelines for interpretation and reporting, Histopathology, vol.69, 4, 2016,pp 680-686
2017Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancerLee, Cheok; O'Toole, Sandra; Byrne, David; et al, Various; Fellowes, Andrew; Hewitt, Chelsee; Kader, Tanjina; Mir Arnau, Gisela; Pang, Jia-Min B.; Savas, Peter; Takano, E; Vedururu, Ravikiran; Central Clinical School: Medicine; Central Clinical School: PathologyBreast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer, Modern Pathology, vol.30, 7, 2017,pp 952-963
2014c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancerArmstrong, Nicola Joy; Naylor, Matthew; O'Toole, Sandra; Baker, Laura; Cowley, Mark; Herschkowitz, Jason I; Hui, Mun; Junankar, Simon; Kaplan, Warren; Lakhani, Sunil R.; McFarland, Andrea; Morey, Adrienne; Nair, Radhika; Nguyen, Akira; Nicolic, I; Ormandy, Christopher J.; Perou, Charles M; Pfefferle, Adam; Roden, Daniel; Selinger, Christina; Shah, Jaynish; Swarbrick, A.; Teo, W S; Usary, Jerry E; Yang, J; Ye, S; Mathematics & Statistics; School of Medical Sciences: Physiology; Central Clinical School: Pathologyc-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer, Oncogene, vol.33, 30, 2014,pp 3992-4002
2015Cell cycle marker expression in benign and malignant intraductal papillary lesions of the breast.Barnes, Elizabeth; Beith, Jane; Carmalt, Hugh; Chan, Charles; Cooper, Caroline; Gluch, Laurence; O'Toole, Sandra; West, Richard; Caldon, C. E.; Loh, Seow Foong; Selinger, Christina; NH&MRC Clinical Trials Centre; Central Clinical School: Medicine; Concord Clinical School: Surgery; Concord Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: SurgeryCell cycle marker expression in benign and malignant intraductal papillary lesions of the breast., Journal of Clinical Pathology, vol.68, 3, 2015,pp 187-191
2013Classification, morphology and molecular pathology of premalignant lesions of the pancreasCooper, Caroline; Kench, James; O'Toole, Sandra; Central Clinical School: Pathology; School of Medical Sciences: Pathology; Central Clinical School: PathologyClassification, morphology and molecular pathology of premalignant lesions of the pancreas, Pathology - Journal of the RCPA, vol.45, 3, 2013,pp 286-304
2014Concordant BRAFV600E mutation status in primary melanomas and associated naevi: implications for mutation testing of primary melanomasKakavand, Hojabr; Kefford, Richard (Rick); Long, Georgina; O'Toole, Sandra; Scolyer, Richard; Thompson, John; Wilmott, James; Crainic, Oana; Lum, Trina; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Pathology; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryConcordant BRAFV600E mutation status in primary melanomas and associated naevi: implications for mutation testing of primary melanomas, Pathology, vol.46, 3, 2014,pp 193-198
2014Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanomaCarlino, Matteo; Hamilton, Anne; Haydu, Lauren; Kakavand, Hojabr; Kefford, Richard (Rick); Long, Georgina; Menzies, Alexander Maxwel; O'Toole, Sandra; Scolyer, Richard; Thompson, John; Yu, Bing; Cooper, Wendy; Ng, C; Western Clinical School: Medicine (Westmead); Central Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: MedicineCorrelation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma, British Journal of Cancer, vol.111, 2, 2014,pp 292-299
2010Cytoplasmic localization of beta-catenin is a marker of poor outcome in breast cancer patients.McNeil, Catriona; O'Toole, Sandra; Crea, Paul; Lopez-Knowles, Elena; Millar, E.; Musgrove, Elizabeth A.; Sutherland, Robert L.; Zardawi, Sarah J; Western Clinical School: Medicine (Westmead); Central Clinical School: PathologyCytoplasmic localization of beta-catenin is a marker of poor outcome in breast cancer patients., Cancer Epidemiology, Biomarkers & Prevention, vol.19, 1,pp 301-309
2015A Detailed Clinicopathologic Study of ALK-translocated Papillary Thyroid CarcinomaAniss, Ahmad; Clifton-Bligh, Roderick; Delbridge, Leigh; Fraser, Sheila; Gill, Anthony; Learoyd, Diana; O'Neill, Christine; O'Toole, Sandra; Robinson, Bruce; Sidhu, Stan; Sywak, Mark; Chou, Angela; Clarkson, Adele; Cussigh, Carmen; Farzin, Mahtab; Selinger, Christina; Sioson, Loretta; Toon, Christopher; Watson, Nicole; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Surgery; Surgery; Northern Clinical School: Pathology; Northern Clinical School: Medicine; Northern Clinical School: Surgery; Central Clinical School: Pathology; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: SurgeryA Detailed Clinicopathologic Study of ALK-translocated Papillary Thyroid Carcinoma, American Journal of Surgical Pathology, vol.39, 5, 2015,pp 652-659
2016Diagnostic and prognostic utility of Mastermind-like 2 (MAML2) gene rearrangement detection by fluorescent in situ hybridization (FISH) in mucoepidermoid carcinoma of the salivary glandsClark, Jonathan; Gupta, Ruta; O'Toole, Sandra; Ekmejian, Rafael; Eviston, Timothy J; Gao, Kan; Luk, Peter; Lum, Trina; Selinger, Christina; Tay, Jessica; Wykes, James; Central Clinical School: Surgery; School of Medical Sciences: Pathology; Central Clinical School: PathologyDiagnostic and prognostic utility of Mastermind-like 2 (MAML2) gene rearrangement detection by fluorescent in situ hybridization (FISH) in mucoepidermoid carcinoma of the salivary glands, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, vol.121, 5, 2016,pp 530-541
2016Diagnostic and prognostic utility of Mastermind-like 2 (MAML2) gene rearrangement detection by fluorescent in situ hybridization (FISH) in mucoepidermoid carcinoma of the salivary glandsClark, Jonathan; Gupta, Ruta; O'Toole, Sandra; Ekmejian, Rafael; Eviston, Timothy J; Gao, Kan; Luk, Peter; Lum, Trina; Selinger, Christina; Tay, Jessica; Wykes, James; Central Clinical School: Surgery; School of Medical Sciences: Pathology; Central Clinical School: PathologyDiagnostic and prognostic utility of Mastermind-like 2 (MAML2) gene rearrangement detection by fluorescent in situ hybridization (FISH) in mucoepidermoid carcinoma of the salivary glands, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, vol.121, 5, 2016,pp 530-541
2013EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinomaGill, Anthony; Horvath, Lisa; McCaughan, Brian; O'Toole, Sandra; Trent, Ronald; Yip, Po Yee; Yu, Bing; Clarkson, A; Cooper, Wendy; Farzin, M; Kench, James; Kohonen-Corish, Maija R.J.; Lum, Trina; Mercorella, B; Ng, Chiu Chin; Deans Unit: (CIPHER); Central Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Medicine; Medicine; Central Clinical School: MedicineEGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma, Journal of Clinical Pathology (JCP Online), vol.66, 9, 2013,pp 744-748