Browsing by Author Mun, Hee-Chang

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Issue DateTitleAuthor(s)Citation
2009Adenomatous human parathyroid cells exhibit impaired sensitivity to L-amino acidsBrennan, Sarah; Conigrave, Arthur; Delbridge, Leigh; Mun, Hee-Chang; Brown, Edward M; Wilkinson, Margaret; Molecular Bioscience; Molecular Bioscience; Northern Clinical School: Surgery; Molecular BioscienceAdenomatous human parathyroid cells exhibit impaired sensitivity to L-amino acids, Journal of Clinical Endocrinology and Metabolism, vol.94, 9, 2009,pp 3567-3574
2007Allosteric activation of the extracellular Ca2+- sensing receptor by L-amino acids enhances ERK1/2 phosphorylation.Conigrave, Arthur; Culverston, Emma; Lee, Heather; Lewis, Narelle; Mason, Rebecca; Mun, Hee-Chang; Crouch, Michael F; Molecular & Microbial Bioscien; School of Medical Sciences: Physiology; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; School of Medical Sciences: Physiology; Molecular & Microbial BioscienAllosteric activation of the extracellular Ca2+- sensing receptor by L-amino acids enhances ERK1/2 phosphorylation., Biochemical Journal, vol.404,(1),2007,pp 141-149
2011Allosteric Modulation of the Calcium-sensing Receptor by y-Glutamyl Peptides Inhibition of PTH Secretion, Suppression of Intracellular cAMP Levels and A Common Mechanism of Action with L-Amino AcidsAvlani, Vimesh Ashvinkumar; Broadhead, Geoffrey; Church, William; Conigrave, Arthur; Delbridge, Leigh; Jourdon, Orane; Mun, Hee-Chang; Christopoulos, Arthur; Molecular Bioscience; Molecular Bioscience; Pharmacy; Molecular Bioscience; Northern Clinical School: Surgery; Molecular Bioscience; Molecular BioscienceAllosteric Modulation of the Calcium-sensing Receptor by y-Glutamyl Peptides Inhibition of PTH Secretion, Suppression of Intracellular cAMP Levels and A Common Mechanism of Action with L-Amino Acids, Journal of Biological Chemistry, vol.286, 11, 2011,pp 8786-8797
2007Aromatic L-amino Acids activate the calcium-sensing receptorConigrave, Arthur; Lok, Hiu; Mun, Hee-Chang; School of Molecular Bioscience (SMB); School of Medical Sciences: Biomedical Sciences; School of Molecular Bioscience (SMB)Aromatic L-amino Acids activate the calcium-sensing receptor, The Journal of Nutrition, vol.137, Supplement, 2007,pp 1524S-1527S
2003Autosomal dominant hypocalcemia: a novel activating mutation (E604K) in the cysteine-rich domain of the calcium-sensing receptorConigrave, Arthur; Franks, Alison; Harris, Leslie; Lewis, Narelle; Mun, Hee-Chang; Cardinal, John W.; Prins, J B; Tan, Y M; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Biomedical Sciences; Molecular & Microbial Bioscien; Molecular & Microbial BioscienAutosomal dominant hypocalcemia: a novel activating mutation (E604K) in the cysteine-rich domain of the calcium-sensing receptor, The Journal of Clinical Endocrinology & Metabolism, vol.88,(2),2003,pp 605-610
2013Calcium-sensing receptor-dependent activation of CREB phosphorylation in HEK293 cells and human parathyroid cellsAvlani, Vimesh; Conigrave, Arthur; Delbridge, Leigh; Ma, Wenting; Mun, Hee-Chang; Christopoulos, Arthur; Leach, Katie; Molecular Bioscience; Molecular Bioscience; Northern Clinical School: Surgery; Molecular Bioscience; Molecular BioscienceCalcium-sensing receptor-dependent activation of CREB phosphorylation in HEK293 cells and human parathyroid cells, American Journal of Physiology: Endocrinology and Metabolism (Print), vol.304, 10, 2013,pp E1097-E1104
2005A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing.Clifton-Bligh, Roderick; Collyer, Charles; Conigrave, Arthur; Culverston, Emma; Franks, Alison; Mun, Hee-Chang; Northern Clinical School: Medicine; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; School of Medical Sciences: Physiology; Molecular & Microbial Bioscien; Molecular & Microbial BioscienA double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing., Journal of Biological Chemistry, vol.280,(32),2005,pp 29067-29072
2009Effectors of the frequency of calcium oscillations in HEK-293 cells: wavelet analysis and a computer modelBrennan, S; Conigrave, Arthur; Kuchel, Philip; Mun, Hee-Chang; Szekely, David; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienEffectors of the frequency of calcium oscillations in HEK-293 cells: wavelet analysis and a computer model, European Biophysics Journal, vol.Online Pub,(DOI 10.1007/s00249-009-0469-2),2009,pp N/A-N/A
2013Identification and characterization of D410E, a novel mutation in the loop 3 domain of CASR, in autosomal dominant hypocalcemia and a therapeutic approach using a novel calcilytic, AXT914Mun, Hee-Chang; Baek, Hae Lim; Eom, Young Sil; Hong, Suntaek; Jung, Tae Sik; Kim, Chul Hoon; Lee, Sihoon; Park, So Young; Molecular BioscienceIdentification and characterization of D410E, a novel mutation in the loop 3 domain of CASR, in autosomal dominant hypocalcemia and a therapeutic approach using a novel calcilytic, AXT914, Clinical Endocrinology, vol.78, 5, 2013,pp 687-693
2010Increased Receptor Stimulation Elicits Differential Calcium-sensing Receptor(T888) DephosphorylationConigrave, Arthur; Mun, Hee-Chang; Atkinson-Dell, Rebecca; Campion, Katherine; McCormick, Wanda; Ward, Donald; School of Molecular Bioscience; School of Molecular BioscienceIncreased Receptor Stimulation Elicits Differential Calcium-sensing Receptor(T888) Dephosphorylation, Journal of Biological Chemistry, vol.285, 19,pp 14170-14177
2014Invasive toxic prey may imperil the survival of an iconic giant lizard, the Komodo dragonConigrave, Arthur; Madsen, Thomas; Mun, Hee-Chang; Ujvari, Beata; Ciofi, Claudio; Molecular Bioscience; Biological Sciences; Molecular Bioscience; Vet Science FacultyInvasive toxic prey may imperil the survival of an iconic giant lizard, the Komodo dragon, Pacific Conservation Biology, vol.20, 4, 2014,pp 363-365
2013Isolation breeds naivety: Island living robs Australian varanid lizards of toad-toxin immunity via four-base-pair mutationBray, Alessandra; Conigrave, Arthur; Madsen, Thomas; Mun, Hee-Chang; Ujvari, Beata; Halling, Petter; Osterkamp, Jens; Molecular Bioscience; Molecular Bioscience; Biological Sciences; Molecular Bioscience; Vet Science FacultyIsolation breeds naivety: Island living robs Australian varanid lizards of toad-toxin immunity via four-base-pair mutation, Evolution, vol.67, 1, 2013,pp 289-294
2004L-Amino Acids Regulate Parathyroid Hormone SecretionConigrave, Arthur; Delbridge, Leigh; Mun, Hee-Chang; Brown, Edward M; Quinn, Stephen J; Wilkinson, Margaret; Molecular & Microbial Bioscien; Northern Clinical School: Surgery; Molecular & Microbial BioscienL-Amino Acids Regulate Parathyroid Hormone Secretion, Journal of Biological Chemistry, vol.279,(37),2004,pp 38151-38159
2015Pathophysiologic changes in extracellular pH modulate parathyroid calcium-sensing receptor activity and secretion via a histidine-independent mechanismConigrave, Arthur; Delbridge, Leigh; Mun, Hee-Chang; Atkinson-Dell, Rebecca; Bin Khayat, Mohd Ezuan; Campion, Katherine; McCormick, Wanda; Steward, Martin C.; Ward, Donald; Warwicker, Jim; Molecular Bioscience; Northern Clinical School: Surgery; Molecular BiosciencePathophysiologic changes in extracellular pH modulate parathyroid calcium-sensing receptor activity and secretion via a histidine-independent mechanism, Journal of the American Society of Nephrology, vol.26, 9, 2015,pp 2163-2171
2007Physiological significance of L-amino acid sensing by extracellular Ca(2+)-sensing receptorsBrennan, S; Conigrave, Arthur; Mun, Hee-Chang; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienPhysiological significance of L-amino acid sensing by extracellular Ca(2+)-sensing receptors, Biochemical Society Transactions, vol.35,(5),2007,pp 1195-1198
2015Receptor expression modulates calcium-sensing receptor mediated intracellular Ca2+ mobilizationBrennan, Sarah; Conigrave, Arthur; Kuchel, Philip; Mun, Hee-Chang; Christopoulos, Arthur; Leach, Katie; Molecular Bioscience; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceReceptor expression modulates calcium-sensing receptor mediated intracellular Ca2+ mobilization, Endocrinology, vol.156, 4, 2015,pp 1330-1342
2016Structural mechanism of ligand activation in human calcium-sensing receptorBrennan, Sarah; Brown, Alice; Conigrave, Arthur; Mun, Hee-Chang; Bush, Martin; Cao, Baohua; Chang, Donald; Chen, Yan; Cheng, Tat; Colecraf, Henry M; Geng, Yong; Kurinov, Igor; McDonald, Patricia; Mosyak, Lidia; Nguyen, Trang; Quick, Matthias; Sturchler, Emmanuel; Subramanyam, Prakash; Zuo, Hao; Molecular Bioscience; NH&MRC Clinical Trials Centre; Molecular Bioscience; Molecular BioscienceStructural mechanism of ligand activation in human calcium-sensing receptor, eLife, vol.5, N/A, 2016,pp 1-25
2016Structural mechanism of ligand activation in human calcium-sensing receptorBrennan, Sarah; Brown, Alice; Conigrave, Arthur; Mun, Hee-Chang; Bush, Martin; Cao, Baohua; Chang, Donald; Chen, Yan; Cheng, Tat; Colecraf, Henry M; Geng, Yong; Kurinov, Igor; McDonald, Patricia; Mosyak, Lidia; Nguyen, Trang; Quick, Matthias; Sturchler, Emmanuel; Subramanyam, Prakash; Zuo, Hao; Molecular Bioscience; NH&MRC Clinical Trials Centre; Molecular Bioscience; Molecular BioscienceStructural mechanism of ligand activation in human calcium-sensing receptor, eLife, vol.5, N/A, 2016,pp 1-25
2005Surgery for hyperparathyroidism: does morphology or function matter most?Conigrave, Arthur; Delbridge, Leigh; Mun, Hee-Chang; Wilkinson, Margaret; Molecular & Microbial Bioscien; Northern Clinical School: Surgery; Molecular & Microbial BioscienSurgery for hyperparathyroidism: does morphology or function matter most?, Surgery, vol.138,(6),2005,pp 1111-1120
2004The Venus Fly Trap Domain Of The Extracellular Ca2+-Sensing Receptor Is Required For L-Amino Acid SensingConigrave, Arthur; Culverston, Emma; Franks, Alison; Mun, Hee-Chang; Krapcho, Karen; Nemeth, Edward F; Molecular & Microbial Bioscien; School of Medical Sciences: Physiology; Molecular & Microbial Bioscien; Molecular & Microbial BioscienThe Venus Fly Trap Domain Of The Extracellular Ca2+-Sensing Receptor Is Required For L-Amino Acid Sensing, Journal of Biological Chemistry, vol.279,(50),2004,pp 51739-51744