Browsing by Author Moussa, Iman

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Issue DateTitleAuthor(s)Citation
2010Design, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligandsBanister, Samuel; Beinat, Corinne; Giboureau, Nicolas; Kassiou, Michael; Moussa, Iman; Reynolds, Aaron; Chemistry; Chemistry; Medical Radiation Sciences; Medical Radiation Sciences; Chemistry; ChemistryDesign, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands, Journal of Medicinal Chemistry, vol.53, 16,pp 6228-6239
2011Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine sigma(1) receptor ligandsAkladios, Fady; Banister, Samuel; Chua, Sook; Kassiou, Michael; Moussa, Iman; Chemistry; Chemistry; School of Medical Sciences: Brain & Mind Research Institute; Medical Imaging and Radiation Sciences; ChemistryEffects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine sigma(1) receptor ligands, Bioorganic & Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, vol.21, 19, 2011,pp 5707-5710
2012Exploration of ring size in a series of cyclic vicinal diamines with sigma(1) receptor-affinityBanister, Samuel; Doddareddy, Munikumar; Kassiou, Michael; Manoli, Miral; Moussa, Iman; Cui, Jinquan; Mach, Robert H.; Chemistry; Brand Management; Medical Imaging and Radiation Sciences; Medical Radiation Sciences; ChemistryExploration of ring size in a series of cyclic vicinal diamines with sigma(1) receptor-affinity, Bioorganic & Medicinal Chemistry Letters, vol.22, 17, 2012,pp 5493-5497
2010Insights into structure-activity relationships and CNS therapeutic applications of NR2B selective antagonistsBanister, Samuel; Beinat, Corinne; Kassiou, Michael; McErlean, Christopher; Moussa, Iman; Reynolds, Aaron; Chemistry; Chemistry; Medical Imaging and Radiation Sciences; Chemistry; Chemistry; ChemistryInsights into structure-activity relationships and CNS therapeutic applications of NR2B selective antagonists, Current Medicinal Chemistry, vol.17, 34,pp 4166-4190
2011Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivityBanister, Samuel; Chua, Sook; Jorgensen, William; Kassiou, Michael; Moussa, Iman; Chemistry; School of Medical Sciences: Brain & Mind Research Institute; Chemistry; Medical Imaging and Radiation Sciences; ChemistryMolecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivity, Bioorganic & Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, vol.21, 12, 2011,pp 3622-3626
2010Oxo-bridged isomers of aza-trishomocubane sigma (o) receptor ligands: Synthesis, in vitro binding, and molecular modelingBanister, Samuel; Jordan, Meredith; Kassiou, Michael; Moussa, Iman; Coster, Mark J; Medical Radiation Sciences; Chemistry; Medical Imaging and Radiation Sciences; ChemistryOxo-bridged isomers of aza-trishomocubane sigma (o) receptor ligands: Synthesis, in vitro binding, and molecular modeling, Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, vol.20, 1, 2010,pp 145-148
2011Synthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N'-[4-(2-fluoroethoxy)benzyl]piperazine, a novel σ1 receptor PET imaging agentBanister, Samuel; Giboureau, Nicolas; Kassiou, Michael; Meikle, Steven; Moussa, Iman; Chemistry; Medical Imaging and Radiation Sciences; Medical Imaging and Radiation Sciences; Medical Imaging and Radiation Sciences; ChemistrySynthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N'-[4-(2-fluoroethoxy)benzyl]piperazine, a novel σ1 receptor PET imaging agent, Bioorganic & Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, vol.21, 22, 2011,pp 6820-6823
2011Trishomocubane as a Scaffold for the Development of Selective Dopamine Transporter (DAT) LigandsBanister, Samuel; Beinat, Corinne; Jorgensen, William; Kassiou, Michael; Moussa, Iman; Reynolds, Aaron; Schiavini, Paolo; Chemistry; Chemistry; Chemistry; Medical Imaging and Radiation Sciences; Chemistry; Chemistry; ChemistryTrishomocubane as a Scaffold for the Development of Selective Dopamine Transporter (DAT) Ligands, Bioorganic & Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, vol.21, 1, 2011,pp 38-41