Browsing by Author Merlot, Angelica

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Issue DateTitleAuthor(s)Citation
2015Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in diseaseBae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineCellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease, Biochimica et Biophysica Acta. General Subjects, vol.1853, 5, 2015,pp 1130-1144
2013Cellular Uptake of the Antitumor Agent Dp44mT Occurs via a Carrier/Receptor-Mediated MechanismKalinowski, Danuta; Menezes, Sharleen; Merlot, Angelica; Pantarat, Namfon; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Bosch Institute; Western Clinical School: Westmead Millennium Institute; School of Medical Sciences: Pathology; MedicineCellular Uptake of the Antitumor Agent Dp44mT Occurs via a Carrier/Receptor-Mediated Mechanism, Molecular Pharmacology, vol.84, 6, 2013,pp 911-924
2015Duodenal cytochrome b (DCYTB) in Iron metabolism: An update on function and regulationBae, Dong-Hun; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desmond; Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pharmacology; School of Medical Sciences: PathologyDuodenal cytochrome b (DCYTB) in Iron metabolism: An update on function and regulation, Nutrients, vol.7, 4, 2015,pp 2274-2296
2014Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transitionKalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Mills, Thomas; Richardson, Desi (Des); Saleh Moussa, Rayan; Shafie, Nurul; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyExpanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transition, Biochimica et Biophysica Acta-Reviews on Cancer, vol.1845, 2, 2014,pp 166-181
2016Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxiaChiang, Shannon; Huang, Michael; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyFrataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia, Clinical Science, vol.130, 11, 2016,pp 853-870
2016Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT)Arzuman, Laila; Gutierrez, Elaine; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Lok, Hiu; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Seebacher, Nicole; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Biological SciencesLysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), BBA: Biochimica et Biophysica Acta - Molecular Cell Research, vol.1863, 7 Pt A, 2016,pp 1665-1681
2016Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinaseJansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Shafie, Nurul; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinase, Biochemical Pharmacology, vol.109, N/A, 2016,pp 27-47
2016Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinaseJansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Shafie, Nurul; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinase, Biochemical Pharmacology, vol.109, N/A, 2016,pp 27-47
2010Membrane Transport and Intracellular Sequestration of Novel Thiosemicarbazone Chelators for the Treatment of CancerKalinowski, Danuta; Lovejoy, David; Merlot, Angelica; Pantarat, Namfon; Richardson, Desi; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; Western Clinical School: Westmead Millennium Institute; School of Medical Sciences: PathologyMembrane Transport and Intracellular Sequestration of Novel Thiosemicarbazone Chelators for the Treatment of Cancer, Molecular Pharmacology, vol.78, 4,pp 675-684
2015The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targetsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Jin, Runsen; Liu, Wensheng; Peng, Zhihai; Wang, Puxiongzhi; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targets, Oncotarget, vol.6, 34, 2015,pp 35522-35541
2015The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targetsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Jin, Runsen; Liu, Wensheng; Peng, Zhihai; Wang, Puxiongzhi; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targets, Oncotarget, vol.6, 34, 2015,pp 35522-35541
2013Novel Chelators for Cancer Treatment: Where Are We Now?Kalinowski, Danuta; Merlot, Angelica; Richardson, Desi (Des); School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PathologyNovel Chelators for Cancer Treatment: Where Are We Now?, Antioxidants & redox signaling, vol.18, 8, 2013,pp 973-1006
2015Novel Thiosemicarbazones Regulate the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway: Inhibition of Constitutive and Interleukin 6-Induced Activation by Iron Depletion.Kalinowski, Danuta; Kovacevic, Zaklina; Lui, Goldie Yuan Lam; Menezes, Sharleen; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineNovel Thiosemicarbazones Regulate the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway: Inhibition of Constitutive and Interleukin 6-Induced Activation by Iron Depletion., Molecular Pharmacology, vol.87, 3, 2015,pp 543-560
2015Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cellsDoddareddy, Munikumar; Fordham, Ashleigh; Hibbs, David; Huang, Michael; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Ong, Jennifer; Pantarat, Namfon; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Bosch Institute; Pharmacy; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; Pharmacy; Western Clinical School: Westmead Institute for Medical Res; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyPotentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells, Oncotarget, vol.6, 12, 2015,pp 10374-10398
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2016Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeuticsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desmond; Sahni, Sumit; Stefani, Christian; Anderson, Gregory; Chua, Anita; Ganz, Tomas; Lee, C Soon; Olynyk, John K; Subramaniam, Nathan; Toyokuni, Shinya; Trinder, Debbie; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyRedox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics, Biochimica et Biophysica Acta, vol.1863, 4, 2016,pp 727-748
2015The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazonesFouani, Leyla; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; Seebacher, Nicole; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; Medicine; Biological SciencesThe renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazones, Pharmacological Research, vol.100, N/A, 2015,pp 255-260