Browsing by Author Manos-Turvey, Alexandra

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Issue DateTitleAuthor(s)Citation
2012Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosisManos-Turvey, Alexandra; Payne, Richard; Baker, Edward; Bulloch, Esther; Chi, Gamma; Evans, Genevieve L.; Johnston, Jodie; Lott, J. Shaun; O'Connor, Patrick D.; Chemistry; ChemistryImplications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis, Biochemistry, vol.51, 24, 2012,pp 4868-4879
2010Inhibition studies of mycobacterium tuberculosis salicylate synthase (Mbtl)Manos-Turvey, Alexandra; Payne, Richard; Rutledge, Peter; Baker, Edward; Bulloch, Esther; Lott, J. Shaun; Chemistry; Chemistry; ChemistryInhibition studies of mycobacterium tuberculosis salicylate synthase (Mbtl), ChemMedChem: chemistry enabling drug discovery, vol.5, 7,pp 1067-1079
2015Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complexManos-Turvey, Alexandra; Payne, Richard; Baker, Edward; Bashiri, Ghader; Bulloch, Esther; Castell, Alina; Evans, Genevieve L.; Goldstone, David C.; Jirgis, Ehab N.M.; Johnston, Jodie; Kleinboelting, Silke; Lott, J. Shaun; Ramsay, Rochelle J.; Chemistry; ChemistryStructure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex, Acta Crystallographica. Section D: Biological Crystallography, vol.D71, 11, 2015,pp 2297-2308
2012Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active siteBritton, Warwick; Cergol, Katie; Manos-Turvey, Alexandra; Pang, Angel; Payne, Richard; Salam, Noeris; West, Nicholas; Baker, Edward; Bulloch, Esther; Chi, Gamma; Lott, J. Shaun; Central Clinical School: Centenary Institute; Chemistry; Chemistry; Central Clinical School: Centenary Institute; Chemistry; Pharmacy; Central Clinical School: Centenary InstituteSynthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site, Organic and Biomolecular Chemistry, vol.10, 46, 2012,pp 9223-9236
2015Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agentsManos-Turvey, Alexandra; Payne, Richard; Watson, Emma; Avery, Vicky; Baell, Jonathan B.; Jones, Amy J.; Kaiser, Marcel; Sykes, Melissa; Chemistry; Chemistry; ChemistrySynthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents, MedChemComm (Medicinal Chemistry Communications), vol.6, 3, 2015,pp 403-406
2011The TB Structural Genomics Consortium: A decade of progressManos-Turvey, Alexandra; Payne, Richard; Baker, Edward; Bruning, John; Bulloch, Esther; Chim, Nicholas; Eisenberg, David; Goulding, Celia; Habel, Jeff; Hung, Li-Wei; James, Michael; Johnston, Jodie; Kim, Chang-Yub; Kim, Haelee; Krieger, Inna; Li, Hongye; Lott, J. Shaun; Miallau, Linda; Morse, Robert; Sacchettini, James; Sankaranarayanan, Ramasamy; Swanson, Stephanie; Terwilliger, Thomas; Chemistry; ChemistryThe TB Structural Genomics Consortium: A decade of progress, Tuberculosis, vol.91, 2, 2011,pp 155-172