Browsing by Author Manetsch, Melanie

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Issue DateTitleAuthor(s)Citation
2009Asthma and Airway Remodelling: Targeting Mitogen-activated Protein Kinases as Future TherapeuticsAmmit, Alaina; Manetsch, Melanie; Ramsay, Emma; Pharmacy; Pharmacy; PharmacyAsthma and Airway Remodelling: Targeting Mitogen-activated Protein Kinases as Future Therapeutics in ISS2009: Genes to Galaxies, The Science Foundation of Physics within the University of Sydney, 2009, pp. 170-181
2012Corticosteroids and B2-agonists upregulate mitogen-activated protein kinase phosphatase 1: in vitro mechanismsAmmit, Alaina; Che, W; Ge, Qi; Hibbs, David; Manetsch, Melanie; Ramsay, Emma; Seidel, Petra; King, E; Newton, Robert; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; PharmacyCorticosteroids and B2-agonists upregulate mitogen-activated protein kinase phosphatase 1: in vitro mechanisms, British Journal of Pharmacology, vol.166, 7, 2012,pp 2049-2059
2014Corticosteroids Inhibit Sphingosine 1-Phosphate–Induced Interleukin-6 Secretion from Human Airway Smooth Muscle via Mitogen-Activated Protein Kinase Phosphatase 1–Mediated Repression of Mitogen and Stress-Activated Protein Kinase 1Alkhouri, Hatem; Ammit, Alaina; Armour, Carol; Che, Angelina (Wen Chi); Ge, Qi; Manetsch, Melanie; Parmentier, Johannes; Ramsay, Emma; Seidel, Petra; Pharmacy; Pharmacy; Central Clinical School: Woolcock Inst. of Medical Research; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; PharmacyCorticosteroids Inhibit Sphingosine 1-Phosphate–Induced Interleukin-6 Secretion from Human Airway Smooth Muscle via Mitogen-Activated Protein Kinase Phosphatase 1–Mediated Repression of Mitogen and Stress-Activated Protein Kinase 1, American Journal of Respiratory Cell and Molecular Biology, vol.50, 2, 2014,pp 358-368
2013Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 CellsCairns, Rose; Chan, Karen; Darabi, Masoud; Grewal, (Ranjit) Thomas; Hoque, Monira; Manetsch, Melanie; Mulay, Vishwaroop; Rye, Kerry-Anne; Wood, Peta; Alvarez-Guaita, Anna; Enrich, Carlos; Heeren, Joerg; Rentero, Carles; Reverter, M; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Central Clinical School: Heart Research Institute; PharmacyInhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 Cells, PLoS One, vol.8, 4, 2013,pp 1-10
2013Long-acting beta2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (mkp-1) in airway smooth muscle cellsAlkhouri, Hatem; Ammit, Alaina; Ge, Qi; Manetsch, Melanie; Patel, Brijeshkumar; Rahman, Mohammad Mostafizur; Ramsay, Emma; Rumzhum, Nowshin; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyLong-acting beta2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (mkp-1) in airway smooth muscle cells, PLoS One, vol.8, 3, 2013,pp 1-9
2012MKP-1: A negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cellsAmmit, Alaina; Che, Angelina (Wen Chi); Chen, Yang; Manetsch, Melanie; Seidel, Petra; Pharmacy; Pharmacy; Central Clinical School: Woolcock Inst. of Medical Research; Pharmacy; PharmacyMKP-1: A negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells, Cellular Signalling, vol.24, 4, 2012,pp 907-913
2010Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscleAmmit, Alaina; Ge, Qi; Manetsch, Melanie; Munoz, Lenka; Ramsay, Emma; Laufer, Stefan; Peifer, Christian; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyNovel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle, European Journal of Pharmacology, vol.635, N/A, 2010,pp 212-218
2013The nucleotide-binding domain and leucine-rich repeat protein-3 inflammasome is not activated in airway smooth muscle upon toll-like receptor-2 ligationAlkhouri, Hatem; Ammit, Alaina; Bunge, Kristin; Im, Hanna; Manetsch, Melanie; Oliver, Brian; Rahman, Mohammad Mostafizur; Rumzhum, Nowshin; Hirota, Jeremy A; Pascoe, Chris D; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; PharmacyThe nucleotide-binding domain and leucine-rich repeat protein-3 inflammasome is not activated in airway smooth muscle upon toll-like receptor-2 ligation, American Journal of Respiratory Cell and Molecular Biology, vol.49, 4, 2013,pp 517-524
2010Proteasomal inhibition upregulates the endogenous MAPK deactivator MKP-1 in human airway smooth muscle: Mechanism of action and effect on cytokine secretionAlkhouri, Hatem; Ammit, Alaina; Bjorkman, Anna; Che, Angelina (Wen Chi); Ge, Qi; Manetsch, Melanie; Moutzouris, John; Ramsay, Emma; Schuster, Friederike; Pharmacy; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; PharmacyProteasomal inhibition upregulates the endogenous MAPK deactivator MKP-1 in human airway smooth muscle: Mechanism of action and effect on cytokine secretion, BBA - Bioenergetics, vol.1803, 3, 2010,pp 416-423
2012Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cellsAmmit, Alaina; Che, W; Ge, Qi; Manetsch, Melanie; Patel, Brijeshkumar; Quante, Timo; Rahman, MD Mahfuzur; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; PharmacySphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cells, Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol.1823, N/A, 2012,pp 1658-1665
2012TLR2 ligand engagement upregulates airway smooth muscle TNF (A) induced cytokine productionAmmit, Alaina; Che, Angelina; Ge, Qi; Heintz, Udo; Hughes, J. Margaret; Manetsch, Melanie; Seidel, Petra; Sukkar, Maria; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyTLR2 ligand engagement upregulates airway smooth muscle TNF (A) induced cytokine production, AJP: Lung Cellular and Molecular Physiology, vol.302, 9, 2012,pp L838-L845