Browsing by Author Madore, Jason

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Issue DateTitleAuthor(s)Citation
2018CD103+ Tumor-Resident CD8+ T Cells Are Associated with Improved Survival in Immunotherapy-Naive Melanoma Patients and Expand Significantly During Anti-PD-1 TreatmentBritton, Warwick; Chen, Jinbiao; Edwards, Jarem; Ferguson, Angela; Gide, Tuba; Hersey, Peter; Hewavisenti, Rehana; Long, Georgina; Madore, Jason; Menzies, Alexander Maxwel; Palendira, Umaimainthan; Quek, Camelia; Saw, Robyn; Scolyer, Richard; Tasker, Annie; Thompson, John; Weninger, Wolfgang; Wilmott, James; Gebhardt, Thomas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Medicine; Physiology; Northern Clinical School: Surgery; Veterinary Science; Northern Clinical School: Medicine; Central Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Pathology; Charles Perkins Centre; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryCD103+ Tumor-Resident CD8+ T Cells Are Associated with Improved Survival in Immunotherapy-Naive Melanoma Patients and Expand Significantly During Anti-PD-1 Treatment, Clinical Cancer Research, vol.24, 13, 2018,pp 3036-3045
2015Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signalingDe Paoli-Iseppi, Ricardo; Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Strbenac, Dario; Tiffen, Jessamy; Wilmott, James; Yang, Jean Yee Hwa; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Mathematics & Statistics; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Mathematics & StatisticsCombining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling, Oncotarget, vol.6, 25, 2015,pp 21507-21521
2015Detailed Pathological Examination of Completion Node Dissection Specimens and Outcome in Melanoma Patients with Minimal (<01 mm) Sentinel Lymph Node MetastasesMadore, Jason; Nieweg, Omgo; Scolyer, Richard; Thompson, John; Vilain, Ricardo; Wang, Shu; Wilmott, James; Holtkamp, Lodewijka H J; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Medicine; Central Clinical School: SurgeryDetailed Pathological Examination of Completion Node Dissection Specimens and Outcome in Melanoma Patients with Minimal (<01 mm) Sentinel Lymph Node Metastases, Annals of Surgical Oncology, vol.22, 9, 2015,pp 2972-2977
2017Dynamic changes in PD-L1 expression and immune infiltrates early during treatment predict response to PD-1 blockade in MelanomaCarlino, Matteo; Guminski, Alexander; Jakrot, Valerie; Kakavand, Hojabr; Kefford, Richard (Rick); Liniker, Elizabeth; Lo, Serigne; Long, Georgina; Madore, Jason; Menzies, Alexander Maxwel; Saw, Robyn; Scolyer, Richard; Thompson, John; Vilain, Ricardo; Wilmott, James; Cooper, Adam J.; Howle, Julie; Kong, Benjamin; Westmead Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Westmead Clinical School: Medicine; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: SurgeryDynamic changes in PD-L1 expression and immune infiltrates early during treatment predict response to PD-1 blockade in Melanoma, Clinical Cancer Research, vol.23, 17, 2017,pp 5024-5033
2014Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium studydeFazio, Anna; Madore, Jason; Bowtell, David D L; Clarke, B; Deen, Suha; et al, Various; Kobel, M; Lele, S; Menon, U; Morrison, C; Odunsi, Kunle; Pharoah, Paul D. P.; Ramus, Susan J.; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Melonoma & Skin Cancer Res. Inst.Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study, British Journal of Cancer, vol.111, 12, 2014,pp 2297-2307
2018HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanomaBeaumont, Kimberley; Ferguson, Peter; Gallagher, Stuart; Gunatilake, Dilini; Haass, Nikolas; Heinemann, Anja; Hersey, Peter; Madore, Jason; Rizos, Helen; Sharp, Danae; Tiffen, Jessamy; Weninger, Wolfgang; Wilmott, James; Central Clinical School: Centenary Institute; Medicine; Westmead Clinical School: Medicine; Northern Clinical School: Kolling Institute; Central Clinical School: Centenary Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryHDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma, International Journal of Cancer, vol.142, 9, 2018,pp 1926-1937
2017MAPK signaling and inflammation link melanoma phenotype switching to induction of CD73 during immunotherapyLong, Georgina; Madore, Jason; Scolyer, Richard; Bald, Tobias; et al, Various; Glodde, Nicole; Landsberg, Jennifer; Lopez-Ramos, Dorys; Ngiow, Shin Foong; Ramis, Bartomeu Bibiloni; Reinhardt, Julia; Schmid-Burgk, Jonathan L; Young, Arabella; Northern Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: PathologyMAPK signaling and inflammation link melanoma phenotype switching to induction of CD73 during immunotherapy, Cancer Research, vol.77, 17, 2017,pp 4697-4709
2015PD-L1 expression in melanoma shows marked heterogeneity within and between patients: Implications for anti-PD-1/PD-L1 clinical trialsHersey, Peter; Kakavand, Hojabr; Kefford, Richard (Rick); Long, Georgina; Madore, Jason; Menzies, Alexander Maxwel; Scolyer, Richard; Thompson, John; Vilain, Ricardo; Wilmott, James; Hyman, Jessica; Yearley, Jennifer H; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: SurgeryPD-L1 expression in melanoma shows marked heterogeneity within and between patients: Implications for anti-PD-1/PD-L1 clinical trials, Pigment Cell & Melanoma Research, vol.28, 3, 2015,pp 245-253
2015PD-L1 expression is a favorable prognostic factor in early stage non-small cell carcinomaBoyer, Michael; Cooper, Wendy Anne; Horvath, Lisa; Kao, Steven; McCaughan, Brian; O'Toole, Sandra; Scolyer, Richard; Vilain, Ricardo; Yip, Po Yee; Yu, Bing; Kohonen-Corish, Maija R.J.; Madore, Jason; Selinger, Christina; Tran, Thang N.; Yearley, Jennifer H; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Medicine; Concord Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Pathology; Central Clinical School: Pathology; Medicine; Central Clinical School: MedicinePD-L1 expression is a favorable prognostic factor in early stage non-small cell carcinoma, Lung Cancer, vol.89, 2, 2015,pp 181-188
2016PD-L1 Negative Status is Associated with Lower Mutation Burden, Differential Expression of Immune-Related Genes, and Worse Survival in Stage III MelanomaLong, Georgina; Madore, Jason; Mann, Graham; Menzies, Alexander Maxwel; Scolyer, Richard; Strbenac, Dario; Thompson, John; Vilain, Ricardo; Wilmott, James; Yang, Jean Yee Hwa; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: Medicine; Central Clinical School: Pathology; Mathematics & Statistics; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Surgery; Mathematics & StatisticsPD-L1 Negative Status is Associated with Lower Mutation Burden, Differential Expression of Immune-Related Genes, and Worse Survival in Stage III Melanoma, Clinical Cancer Research, vol.22, 15, 2016,pp 3915-3923
2016Programmed cell death-ligand 1 expression in oral squamous cell carcinoma is associated with an inflammatory phenotypeBoyer, Michael; Clark, Jonathan; Gupta, Ruta; Madore, Jason; Scolyer, Richard; Chia, Noel; Lum, Trina; Palme, Carsten E.; Satgunaseelan, Laveniya; Central Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: Medicine; Central Clinical School: PathologyProgrammed cell death-ligand 1 expression in oral squamous cell carcinoma is associated with an inflammatory phenotype, Pathology, vol.48, 6, 2016,pp 574-580
2016Programmed death ligand 1 expression in triple-negative breast cancer is associated with tumour-infiltrating lymphocytes and improved outcomeBeith, Jane; Carmalt, Hugh; Chan, Charles; Cooper, Caroline; Gee, Harriet; Gillett, David; Gluch, Laurence; Kennedy, Catherine; McLean, Anna; McNeil, Catriona; O'Toole, Sandra; Scolyer, Richard; Vilain, Ricardo; Walker, Emily; Warrier, Sanjay; Wilmott, James; Beckers, Rhiannon; Harvey, Kate; Holliday, Anne; Madore, Jason; Mak, Cindy; Robbins, Elizabeth; Selinger, Christina; Swarbrick, A.; Central Clinical School: Medicine; Concord Clinical School: Surgery; Concord Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Medicine; Concord Clinical School: Surgery; Central Clinical School: Medicine; Central Clinical School: Surgery; Northern Clinical School: Rehabilitations Studies Unit; Western Clinical School: Medicine (Westmead); Central Clinical School: Pathology; Central Clinical School: Pathology; Central Clinical School: Pathology; Medicine; Central Clinical School: Surgery; Central Clinical School: SurgeryProgrammed death ligand 1 expression in triple-negative breast cancer is associated with tumour-infiltrating lymphocytes and improved outcome, Histopathology, vol.69, 1, 2016,pp 25-34
2015Recurrent inactivating RASA2 mutations in melanomaMadore, Jason; Mann, Graham; Scolyer, Richard; Wilmott, James; Arafeh, Rand; Di Pizio, Antonella; Elkahloun, Abdel; Emmanuel, Rafi; et al, Various; Gartner, Jared; Keren-Paz, Alona; Qutob, Nouar; Rotkoph, Ron; Sindiri, Sivasish; Winograd-Katz, Sabina; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: Pathology; Central Clinical School: SurgeryRecurrent inactivating RASA2 mutations in melanoma, Nature Genetics, vol.47, 12, 2015,pp 1408-1410
2015Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genesGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Mann, Graham; Pupo, Gulietta; Strbenac, Dario; Tiffen, Jessamy; Yang, Jean Yee Hwa; Cullinane, Carleen; Dutton-Regester, Ken; Filli[, Fabian V.; Hayward, Nicholas; McArthur, Grant A.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Mathematics & Statistics; Central Clinical School: Centenary Institute; Mathematics & StatisticsTargeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes, Oncotarget, vol.6, 29, 2015,pp 27023-27036
2017Targeting adenosine in BRAF-mutant melanoma reduces tumor growth and metastasisLong, Georgina; Madore, Jason; Scolyer, Richard; Ahern, Elizabeth; Bald, Tobias; Barkauskas, Deborah; Boyle, Glen M; Chitsazan, Arash; Holzel, Michael; Huntington, Nicholas; Landsberg, Jennifer; Ngiow, Shin Foong; Rautela, Jai; Reinhardt, Julia; Schadendorf, Dirk; Smyth, Mark J; Young, Arabella; Northern Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: PathologyTargeting adenosine in BRAF-mutant melanoma reduces tumor growth and metastasis, Cancer Research, vol.77, 17, 2017,pp OF1-OF13
2017Tumor Suppressor microRNAs Contribute to the Regulation of PD-L1 Expression in Malignant Pleural MesotheliomaBoyer, Michael; Cheng, Yuen Yee; Cooper, Wendy Anne; Kao, Steven; Kirschner, Michaela; Madore, Jason; McCaughan, Brian; Reid, Glen; Scolyer, Richard; van Zandwijk, Nico; Williams, Marissa; Klebe, Sonja; Linton, Anthony; Lum, Trina; Sarun, Kadir; Central Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Central Clinical School: Medicine; Central Clinical School: Medicine; Concord Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Surgery; Concord Clinical School: Medicine; Central Clinical School: Pathology; Concord Clinical School: Medicine; Concord Clinical School: Asbestos Disease Research InstituteTumor Suppressor microRNAs Contribute to the Regulation of PD-L1 Expression in Malignant Pleural Mesothelioma, Journal of Thoracic Oncology, vol.12, 9, 2017,pp 1421-1433
2015UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell CarcinomasDe Paoli-Iseppi, Ricardo; Gill, Anthony; Hruby, George; Madore, Jason; Mann, Graham; Scolyer, Richard; Thompson, John; Wilmott, James; Arnau, Gisela Mir; Colebatch, Andrew J; et al, Various; Fellowes, Andrew; Li, Jason; Lupat, Richard; Schroder, Jan; Semple, Timothy; Vergara, Ismael A; Waldeck, Kelly; Wong, Stephen; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Northern Clinical School: Pathology; Central Clinical School: Medicine; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryUV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas, Cancer Research, vol.75, 24, 2015,pp 5228-5234