Browsing by Author Mach, John

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Issue DateTitleAuthor(s)Citation
2016Acetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure typeCogger, Victoria Carroll; Hilmer, Sarah; Jones, Brett; Kane, Alice; Le Couteur, David; Mach, John; de Cabo, Rafael; Huizer-Pajkos, Aniko; McKenzie, Catriona; Mitchell, Sarah; Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; School of Medical Sciences: Pharmacology; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling InstituteAcetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure type, Experimental Gerontology, vol.73, N/A, 2016,pp 95-106
2016Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of AgingHilmer, Sarah; Kane, Alice; Le Couteur, David; Mach, John; De Cabo, Rafael; Howlett, Susan; Huizer-Pajkos, Aniko; Mitchell, Sarah; Northern Clinical School: Medicine; School of Medical Sciences: Pharmacology; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling InstituteAdverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging, Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.71, 5, 2016,pp 571-577
2016Animal models of frailty: current applications in clinical researchHilmer, Sarah; Mach, John; De Cabo, Rafael; Howlett, Susan; Kane, Alice E; Mitchell, Sarah; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteAnimal models of frailty: current applications in clinical research, Clinical Interventions in Aging, vol.11, N/A, 2016,pp 1519-1529
2017A Comparison of Two Mouse Frailty Assessment ToolsHilmer, Sarah; Huizer-Pajkos, Aniko; Kane, Alice; Le Couteur, David; Mach, John; de Cabo, Rafael; Howlett, Susan; Mitchell, Sarah; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; School of Medical Sciences: Pharmacology; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling InstituteA Comparison of Two Mouse Frailty Assessment Tools, Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.72, 7, 2017,pp 904-910
2014The Effect of Aging on Acetaminophen Pharmacokinetics, Toxicity and Nrf2 in Fischer 344 RatsCogger, Victoria Carroll; Hilmer, Sarah; Jones, Brett; Le Couteur, David; Mach, John; De Cabo, Rafael; Huizer-Pajkos, Aniko; McKenzie, Catriona; Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling InstituteThe Effect of Aging on Acetaminophen Pharmacokinetics, Toxicity and Nrf2 in Fischer 344 Rats, Journals of Gerontology. Series A: Biological Sciences and Medical Sciences, vol.69, 4, 2014,pp 387-397
2016The effect of aging on isoniazid pharmacokinetics and hepatotoxicity in Fischer 344 ratsCogger, Victoria Carroll; Hilmer, Sarah; Jones, Brett; Kane, Alice; Le Couteur, David; Mach, John; Phillips, Leo; de Cabo, Rafael; Huizer-Pajkos, Aniko; McKenzie, Catriona; Mitchell, Sarah; Concord Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; School of Medical Sciences: Pharmacology; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling Institute; School of Medical Sciences: Anatomy & HistologyThe effect of aging on isoniazid pharmacokinetics and hepatotoxicity in Fischer 344 rats, Fundamental and Clinical Pharmacology, vol.30, 1, 2016,pp 23-34
2015The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats.Cogger, Victoria Carroll; Hilmer, Sarah; Jones, Brett; Kane, Alice; Le Couteur, David; Mach, John; de Cabo, Rafael; Huizer-Pajkos, Aniko; McKenzie, Catriona; Mitchell, Sarah; Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; School of Medical Sciences: Pharmacology; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling InstituteThe effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats., Experimental Gerontology, vol.67, N/A, 2015,pp 54-61
2015Factors that Impact on Interrater Reliability of the Mouse Clinical Frailty IndexHilmer, Sarah; Kane, Alice; Boyer, Dawn; De Cabo, Rafael; Gavin, Kristan; Huizer-Pajkos, Aniko; Mach, John; Mitchell, Sarah; Nines, Dawn; Northern Clinical School: Medicine; School of Medical Sciences: PharmacologyFactors that Impact on Interrater Reliability of the Mouse Clinical Frailty Index, Journals of Gerontology. Series A: Biological Sciences and Medical Sciences, vol.70, 6, 2015,pp 694-695
2016N-Acetyl Cysteine does not prevent liver toxicity from chronic low-dose plus subacute high-dose paracetamol exposure in young or old miceCogger, Victoria Carroll; Hilmer, Sarah; Jones, Brett; Kane, Alice; Le Couteur, David; Mach, John; De Cabo, Rafael; Huizer-Pajkos, Aniko; McKenzie, Catriona; Mitchell, Sarah; Concord Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; School of Medical Sciences: Pharmacology; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling InstituteN-Acetyl Cysteine does not prevent liver toxicity from chronic low-dose plus subacute high-dose paracetamol exposure in young or old mice, Fundamental and Clinical Pharmacology, vol.30, 3, 2016,pp 263-275
2016Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistanceCogger, Victoria Carroll; Cordwell, Stuart; Hilmer, Sarah; Le Couteur, David; Mach, John; Mohamad, Mashani; Simpson, Stephen; Solon-Biet, Samantha; Warren, Alessandra; White, Melanie; Boyer, Dawn; Das, Abhirup; de Cabo, Rafael; Fraser, Robin; Li, Shi-Yun; Mitchell, Sarah; Nines, Dawn; Sinclair, David; Wu, Lindsay E; Concord Clinical School: Medicine; School of Life and Environmental Sciences (SOLES); Northern Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling Institute; Concord Clinical School: ANZAC Research Institute; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); Concord Clinical School: ANZAC Research Institute; Molecular BioscienceUltrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance, Aging Cell, vol.15, 4, 2016,pp 706-715