Browsing by Author Laybutt, D. Ross

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Issue DateTitleAuthor(s)Citation
2008Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signalingStevens, Veronica; Akerfeldt, Mia C; Biden, Trevor J; Boubenna, Nacer; Chan, Jeng Yie; Howes, Jennifer; King, Cecile; Laybutt, D. Ross; McGuire, Helen M; Northern Clinical School: MedicineCytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling, Diabetes, vol.57, 11, 2008,pp 3034-3044
2016Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in AdipocytesChaudhuri, Rima; Cooney, Gregory; Humphrey, Sean; James, David; Minard, Annabel; Parker, Benjamin Leo; Stoeckli, Jacqueline; Wong, Martin Kin Lok; Yang, Jean Yee Hwa; Coster, Adelle; Laybutt, D. Ross; Tan, Shi-Xiong; Molecular Bioscience; School of Medical Sciences: School of Medical Sciences; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); Molecular Bioscience; School of Life and Environmental Sciences (SOLES); Physics; Mathematics & StatisticsHyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes, Journal of Biological Chemistry, vol.291, 49, 2016,pp 25629-25640
2016Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in AdipocytesChaudhuri, Rima; Cooney, Gregory; Humphrey, Sean; James, David; Minard, Annabel; Parker, Benjamin Leo; Stoeckli, Jacqueline; Wong, Martin Kin Lok; Yang, Jean Yee Hwa; Coster, Adelle; Laybutt, D. Ross; Tan, Shi-Xiong; Molecular Bioscience; School of Medical Sciences: School of Medical Sciences; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); Molecular Bioscience; School of Life and Environmental Sciences (SOLES); Physics; Mathematics & StatisticsHyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes, The Journal of Biological Chemistry, vol.291, 49, 2016,pp 25629-25640
2016Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cellsGunton, Jenny Elizabeth; Bensellam, Mohammed; Chan, Jeng Yie; Jonas, Jean-Christophe; Laybutt, D. Ross; Luzuriaga, Jude; Maxwell, Emma; West, Phillip; Western Clinical School: Westmead Institute for Medical ResHypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells, Diabetologia, vol.59, 7, 2016,pp 1492-1502
2010Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human isletsBiankin, Andrew; Gunton, Jenny; Hawthorne, Wayne; Kench, James; O'Connell, Philip; Cheng, Kim; Gonzalez, Frank J.; Grey, Shane; Ho, Ken K Y; Kahn, C. Ronald; Kay, Thomas W; Kulkarni, Rohit N.; Lau, Sue; Laybutt, D. Ross; Loudovaris, Thomas; Okada, Terumasa; Scott, Christopher; Shah, Yatrik; Stokes, Rebecca; Wang, Xiaohui; Yim, Sun Hee; School of Public Health: NH&MRC Clinical Trials Centre; School of Molecular Bioscience; Western Clinical School: Westmead Millennium Institute; School of Medical Sciences: Pathology; Western Clinical School: Westmead Millennium InstituteHypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets, Journal of Clinical Investigation, vol.120, 6,pp 2171-2183
2005Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis.Denyer, Gareth; Biden, Trevor J; Busch, Anna K; Cordery, Damien; Gurisik, Ebru; Hughes, William E; Laybutt, D. Ross; Sudlow, Michelle; Molecular & Microbial BioscienIncreased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis., Diabetes, vol.54,(10),2005,pp 2917-2924
2012Mice Deficient in GEM GTPase Show Abnormal Glucose Homeostasis Due to Defects in Beta-Cell Calcium HandlingGunton, Jenny; Cai, Weikang; Cheng, Kim; Cooney, Gregory; et al, Various; Laybutt, D. Ross; Liu, Sue M; Satin, Jon; Satin, Leslie S; Sisavanh, Mary; Stokes, Rebecca; Zhang, Min; Molecular BioscienceMice Deficient in GEM GTPase Show Abnormal Glucose Homeostasis Due to Defects in Beta-Cell Calcium Handling, PLoS One, vol.7, 6, 2012,pp 1-9