Browsing by Author Lane, Darius John Rowland

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Issue DateTitleAuthor(s)Citation
2014The Active Role of Vitamin C in Mammalian Iron Metabolism: Much More Than Just Enhanced Iron Absorption!Lane, Darius John Rowland; Richardson, Desi (Des); School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe Active Role of Vitamin C in Mammalian Iron Metabolism: Much More Than Just Enhanced Iron Absorption!, Free Radical Biology and Medicine, vol.75, C, 2014,pp 69-83
2015Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in diseaseBae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineCellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease, Biochimica et Biophysica Acta. General Subjects, vol.1853, 5, 2015,pp 1130-1144
2015Duodenal cytochrome b (DCYTB) in Iron metabolism: An update on function and regulationBae, Dong-Hun; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desmond; Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pharmacology; School of Medical Sciences: PathologyDuodenal cytochrome b (DCYTB) in Iron metabolism: An update on function and regulation, Nutrients, vol.7, 4, 2015,pp 2274-2296
2014Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transitionKalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Mills, Thomas; Richardson, Desi (Des); Saleh Moussa, Rayan; Shafie, Nurul; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyExpanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transition, Biochimica et Biophysica Acta-Reviews on Cancer, vol.1845, 2, 2014,pp 166-181
2014Fixing frataxin: "ironing out" the metabolic defect in friedreich's ataxiaAnzovino, Amy; Huang, Michael; Lane, Darius John Rowland; Richardson, Desi (Des); School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyFixing frataxin: "ironing out" the metabolic defect in friedreich's ataxia, British Journal of Pharmacology, vol.171, 8, 2014,pp 2174-2190
2016Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxiaChiang, Shannon; Huang, Michael; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyFrataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia, Clinical Science, vol.130, 11, 2016,pp 853-870
2016Glucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug TransporterJansson, Patric; Lane, Darius John Rowland; Richardson, Desi (Des); Seebacher, Nicole; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Biological SciencesGlucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug Transporter, The Journal of Biological Chemistry, vol.291, 8, 2016,pp 3796-3820
2014Glutathione S-Transferase and MRP1 Form an Integrated System Involved in the Storage and Transport of Dinitrosyl-Dithiolato Iron Complexes in CellsKalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Lok, Hiu; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; MedicineGlutathione S-Transferase and MRP1 Form an Integrated System Involved in the Storage and Transport of Dinitrosyl-Dithiolato Iron Complexes in Cells, Free Radical Biology and Medicine, vol.75, N/A, 2014,pp 14-29
2016Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT)Arzuman, Laila; Gutierrez, Elaine; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Lok, Hiu; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Seebacher, Nicole; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Biological SciencesLysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), BBA: Biochimica et Biophysica Acta - Molecular Cell Research, vol.1863, 7 Pt A, 2016,pp 1665-1681
2016Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinaseJansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Shafie, Nurul; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinase, Biochemical Pharmacology, vol.109, N/A, 2016,pp 27-47
2016Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinaseJansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Shafie, Nurul; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinase, Biochemical Pharmacology, vol.109, N/A, 2016,pp 27-47
2014The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cellsBae, Dong-Hun; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; MedicineThe metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells, The Journal of Biological Chemistry, vol.289, 14, 2014,pp 9692-9709
2016The metastasis suppressor, N-MYC downstream-regulated gene-1 (NDRG1), down-regulates the ErbB family of receptors to inhibit downstream oncogenic signaling pathwaysBae, Dong-Hun; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Menezes, Sharleen; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe metastasis suppressor, N-MYC downstream-regulated gene-1 (NDRG1), down-regulates the ErbB family of receptors to inhibit downstream oncogenic signaling pathways, Journal of Biological Chemistry, vol.291, 3, 2016,pp 1029-1052
2015The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targetsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Jin, Runsen; Liu, Wensheng; Peng, Zhihai; Wang, Puxiongzhi; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targets, Oncotarget, vol.6, 34, 2015,pp 35522-35541
2015The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targetsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Jin, Runsen; Liu, Wensheng; Peng, Zhihai; Wang, Puxiongzhi; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targets, Oncotarget, vol.6, 34, 2015,pp 35522-35541
2014Molecular Functions of the Iron-Regulated Metastasis Suppressor, NDRG1, and its Potential as a Molecular Target for Cancer TherapyFang, Bernard; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Park, Kyung Chan; Richardson, Desi (Des); Sahni, Sumit; Central Clinical School: Medicine; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineMolecular Functions of the Iron-Regulated Metastasis Suppressor, NDRG1, and its Potential as a Molecular Target for Cancer Therapy, Biochimica et Biophysica Acta (Molecular and Cell Biology of Lipids), vol.1845, 1, 2014,pp 1-19
2015Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cellsDoddareddy, Munikumar; Fordham, Ashleigh; Hibbs, David; Huang, Michael; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Ong, Jennifer; Pantarat, Namfon; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Bosch Institute; Pharmacy; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; Pharmacy; Western Clinical School: Westmead Institute for Medical Res; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyPotentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells, Oncotarget, vol.6, 12, 2015,pp 10374-10398
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874