Browsing by Author Kovacevic, Zaklina

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 20 of 52  next >
Issue DateTitleAuthor(s)Citation
2015Differential targeting of the cyclin-dependent kinase inhibitor by chelators with anti-proliferative activity in a range of tumor cell-typesKovacevic, Zaklina; Richardson, Desi (Des); Saleh Moussa, Rayan; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDifferential targeting of the cyclin-dependent kinase inhibitor by chelators with anti-proliferative activity in a range of tumor cell-types, Oncotarget, vol.6, 30, 2015,pp 29694-29711
2013Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cellsAssinder, Stephen; Chen, Zhongyan; Dixon, Katie; Dong, Qihan; Kovacevic, Zaklina; Lui, Goldie; Richardson, Desi (Des); Yao, Mu; Zhang, Daohai; School of Medical Sciences: Physiology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; Central Clinical School: Medicine; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; Central Clinical School: Medicine; School of Medical Sciences: PathologyDp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells, British Journal of Cancer, vol.108, 2, 2013,pp 409-419
2016The emerging role of progesterone receptor membrane component 1 (PGRMC1) in cancer biologyKovacevic, Zaklina; Richardson, Desi (Des); Cahill, Michael; Catalano, Susan; Jazayeri, Jalal A; Toyokuni, Shinya; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe emerging role of progesterone receptor membrane component 1 (PGRMC1) in cancer biology, Biochimica et Biophysica Acta, vol.1866, 2, 2016,pp 339-349
2014Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transitionKalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Mills, Thomas; Richardson, Desi (Des); Saleh Moussa, Rayan; Shafie, Nurul; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyExpanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transition, Biochimica et Biophysica Acta-Reviews on Cancer, vol.1845, 2, 2014,pp 166-181
2016Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxiaChiang, Shannon; Huang, Michael; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyFrataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia, Clinical Science, vol.130, 11, 2016,pp 853-870
2014Glutathione S-Transferase and MRP1 Form an Integrated System Involved in the Storage and Transport of Dinitrosyl-Dithiolato Iron Complexes in CellsKalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Lok, Hiu; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; MedicineGlutathione S-Transferase and MRP1 Form an Integrated System Involved in the Storage and Transport of Dinitrosyl-Dithiolato Iron Complexes in Cells, Free Radical Biology and Medicine, vol.75, N/A, 2014,pp 14-29
2017Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signalingKovacevic, Zaklina; Menezes, Sharleen; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyInterplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling, The Journal of Biological Chemistry, vol.292, 31, 2017,pp 12772-12782
2010Investigating the anti-proliferative activity of styrylazanaphthalenes and azanaphthalenedionesKalinowski, Danuta; Kamalapuram, Sishir; Kovacevic, Zaklina; Richardson, Desi; Finster, Jacek; Jampilek, Josef; Knas, Magdalena; Mrozek-Wilczkiewicz, Anna; Musiol, Robert; Polanski, Jaroslaw; Ratuszna, Alicja; Rzeszowska-Wolny, Joanna; Serafin, Katarzyna; Szurko, Agnieszka; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyInvestigating the anti-proliferative activity of styrylazanaphthalenes and azanaphthalenediones, Bioorganic & Medicinal Chemistry: the tetrahedron journal for research at the interface of chemistry and biology, vol.18, 7,pp 2664-2671
2010Investigating the Spectrum of Biological Activity of Ring-Substituted Salicylanilides and CarbamoylphenylcarbamatesKalinowski, Danuta; Kovacevic, Zaklina; Richardson, Desi; Coffey, Aidan; Csollei, Jozef; Guo, Jiahui; Jampilek, Josef; Kralova, Katarina; Mandelova, Zuzana; Otevrel, Jan; Pesko, Matus; Sersen, Frantisek; Vejsova, Marcela; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyInvestigating the Spectrum of Biological Activity of Ring-Substituted Salicylanilides and Carbamoylphenylcarbamates, Molecules, vol.15, 11,pp 8122-8142
2013Iron Chelation: Inhibition of Key Signaling Pathways in the Induction of the Epithelial Mesenchymal Transition in Pancreatic Cancer and Other TumorsKovacevic, Zaklina; Richardson, Alexander; Richardson, Desi (Des); School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PathologyIron Chelation: Inhibition of Key Signaling Pathways in the Induction of the Epithelial Mesenchymal Transition in Pancreatic Cancer and Other Tumors, Critical Reviews in Oncogenesis, vol.18, 5, 2013,pp 409-434
2012The iron chelators Dp44mT and DFO inhibit TGF-B-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1)Chen, Zhiqiang; Kovacevic, Zaklina; Richardson, Desi (Des); Zhang, Daohai; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe iron chelators Dp44mT and DFO inhibit TGF-B-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1), Journal of Biological Chemistry, vol.287, 21, 2012,pp 17016-17028
2012Iron chelators for the treatment of cancerGutierrez, Elaine; Kovacevic, Zaklina; Obeidy, Peyman; Richardson, Desi (Des); Saletta, Federica; Suryo Rahmanto, Yohan; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyIron chelators for the treatment of cancer, Current Medicinal Chemistry, vol.19, 17, 2012,pp 2689-2702
2010Iron Chelators: Development of Novel Compounds with High and Selective Anti-Tumour ActivityKalinowski, Danuta; Kovacevic, Zaklina; Lovejoy, David; Quach, Patricia; Richardson, Desi; Wong, Jennifer; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Molecular BioscienceIron Chelators: Development of Novel Compounds with High and Selective Anti-Tumour Activity, Current Drug Delivery, vol.7, 3,pp 194-207
2013The Iron-Regulated Metastasis Suppressor NDRG1 Targets NEDD4L, PTEN, and SMAD4 and Inhibits the PI3K and Ras Signaling PathwaysChikhani, Sherin; Kovacevic, Zaklina; Lui, Goldie; Richardson, Desi (Des); Sivagurunathan, Sutharshani; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PhysiologyThe Iron-Regulated Metastasis Suppressor NDRG1 Targets NEDD4L, PTEN, and SMAD4 and Inhibits the PI3K and Ras Signaling Pathways, Antioxidants & Redox Signaling, vol.18, 8, 2013,pp 874-887
2008The iron-regulated metastasis suppressor, Ndrg-1: Identification of novel molecular targetsFu, Dong; Kovacevic, Zaklina; Richardson, Desi; School of Medical Sciences: Biomedical Sciences; School of Molecular Bioscience; School of Medical Sciences: PathologyThe iron-regulated metastasis suppressor, Ndrg-1: Identification of novel molecular targets, B B A - General Subjects, vol.1783,(10),2008,pp 1981-1992
2016Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT)Arzuman, Laila; Gutierrez, Elaine; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Lok, Hiu; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Seebacher, Nicole; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Biological SciencesLysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), BBA: Biochimica et Biophysica Acta - Molecular Cell Research, vol.1863, 7 Pt A, 2016,pp 1665-1681
2016Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinaseJansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Shafie, Nurul; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinase, Biochemical Pharmacology, vol.109, N/A, 2016,pp 27-47
2016Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinaseJansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Shafie, Nurul; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2[alpha], IRE1[alpha], ATF6 and calmodulin kinase, Biochemical Pharmacology, vol.109, N/A, 2016,pp 27-47
2017Metals and metastasis: Exploiting the role of metals in cancer metastasis to develop novel anti-metastatic agentsFouani, Leyla; Kovacevic, Zaklina; Menezes, Sharleen; Paulson, Mellow; Richardson, Desi (Des); School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMetals and metastasis: Exploiting the role of metals in cancer metastasis to develop novel anti-metastatic agents, Pharmacological Research, vol.115, N/A, 2017,pp 275-287
2014The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of β-catenin through mechanisms involving FRAT1 and PAK4Jin, Runsen; Kovacevic, Zaklina; Liu, Wensheng; Menezes, Sharleen; Richardson, Desmond; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PharmacologyThe metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of β-catenin through mechanisms involving FRAT1 and PAK4, Journal of Cell Science, vol.127, 14, 2014,pp 3116-3130