Browsing by Author Khachigian, Levon M.

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Showing results 1 to 17 of 17
Issue DateTitleAuthor(s)Citation
2009Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and fasl-fas engagementStocker, Roland; Khachigian, Levon M.; Li, Jian-Mei; Tan, Nicole; School of Medical Sciences: PathologyAngiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and fasl-fas engagement, Circulation Research, vol.105, 5,pp 422-430
2003Animal models of vulnerable plaqueLowe, Harry; Jang, Ik-Kyung; Khachigian, Levon M.; Concord Clinical School: ANZAC Research InstituteAnimal models of vulnerable plaque, Thrombosis and Haemostasis: international journal for vascular biology and medicine, vol.90,(5),2003,pp 774-780
2003Blockade of vascular smooth muscle cell proliferation and intimal thickening after balloon injury by the Sulfated Oligosaccharide PI-88 Phosphomannopentaose Sulfate directly binds FGF-2, blocks cellular signalling and inhibits proliferationLowe, Harry; Bingley, John A.; Brown, Katherine J; Cowden, William B.; et, al; Francis, Douglas J.; Hayward, Ian P.; Khachigian, Levon M.; McGarry, Mark; Parish, Christopher R.; Santiago, Fernando S.; Concord Clinical School: ANZAC Research InstituteBlockade of vascular smooth muscle cell proliferation and intimal thickening after balloon injury by the Sulfated Oligosaccharide PI-88 Phosphomannopentaose Sulfate directly binds FGF-2, blocks cellular signalling and inhibits proliferation, Circulation Research, vol.92,(8),2003,pp e70-e77
2007Brothers in Arms. DNA Enzymes, Short Interfering RNA, and the Emerging Wave of Small-Molecule Nucleic Acid-Based Gene-Silencing StrategiesLowe, Harry; Bhindi, Ravinay; Cairns, Murray J; Chesterman, Colin N; Dass, Crispin R; Fahmy, Roger G; Khachigian, Levon M.; Saravolac, Edward G; Sun, Lun-Quan; Concord Clinical School: ANZAC Research InstituteBrothers in Arms. DNA Enzymes, Short Interfering RNA, and the Emerging Wave of Small-Molecule Nucleic Acid-Based Gene-Silencing Strategies, American Journal of Pathology, vol.171,(4),2007,pp 1079-1088
2011Divergent roles of NF-kB and Egr-1 in flow-dependent restenosis after angioplasty and stentingMurrell, Melanie; Ward, Michael; Khachigian, Levon M.; Medicine; Northern Clinical School: MedicineDivergent roles of NF-kB and Egr-1 in flow-dependent restenosis after angioplasty and stenting, Atherosclerosis, vol.214, 1, 2011,pp 65-72
2006DNAzymes targeting the transcription factor Egr-1 reduce myocardial infarct size following ischemia-reperfusion in rats.Bhindi, Ravinay; Lowe, Harry; Khachigian, Levon M.; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteDNAzymes targeting the transcription factor Egr-1 reduce myocardial infarct size following ischemia-reperfusion in rats., Journal of thrombosis and haemostasis, vol.4,(7),2006,pp 1479-1483
2010Interplay Between Heme Oxygenase-1 and the Multifunctional Transcription Factor Yin Yang 1 in the Inhibition of Intimal HyperplasiaBeck, Konstanze; Ni, Jun; Stocker, Roland; Wang, Yutang; Khachigian, Levon M.; Li, Cheng; Malabanan, Kristine; Santiago, Fernando S.; Wu, Ben J.; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: School of Medical SciencesInterplay Between Heme Oxygenase-1 and the Multifunctional Transcription Factor Yin Yang 1 in the Inhibition of Intimal Hyperplasia, Circulation Research, vol.107, Online: DOI: 10.1161/CIRCRESAHA.110.231985,pp 1-8
2012Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusionBhindi, Ravinay; Lowe, Harry; McMahon, Aisling; Fahmy, Roger G; Khachigian, Levon M.; Northern Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteIntracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion, Journal of Pathology, vol.227, 3, 2012,pp 157-164
2004Low Flow Promotes Instent Intimal Hyperplasia Comparison With Lumen Loss In Balloon-Injured And Uninjured Vessels And The Effects Of The Antioxidant Pyrrolidine Dithiocarbamate.Hanratty, Colm G.; Murrell, Melanie; Ward, Michael; Khachigian, Levon M.; Tsao, Philip S; Northern Clinical School: Medicine; Medicine; Northern Clinical School: MedicineLow Flow Promotes Instent Intimal Hyperplasia Comparison With Lumen Loss In Balloon-Injured And Uninjured Vessels And The Effects Of The Antioxidant Pyrrolidine Dithiocarbamate., Atherosclerosis, vol.177,(2),2004,pp 269-274
2010Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathwayQiao, Liang; Chan, Godfrey Chi Fung; Chen, Jian Liang; Chong, Beng H; Deng, Ruixia; Khachigian, Levon M.; Lian, Qizhou; Luo, Xue Qun; Ma, Ming; Meng, Fan Yi; Yang, Mo; Ye, Jieyu; Western Clinical School: Medicine (Westmead)Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathway, Haematologica: the hematology journal, vol.95, 10,pp 1745-1753
2003Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA bindingCrossley, Paul (Merlin); Newton, Anthea; Chong, Beng H; Eisbacher, Michael; Hogg, Phillip J; Holmes, Melissa; Khachigian, Levon M.; Molecular & Microbial Bioscien; Molecular & Microbial BioscienProtein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding, Molecular and Cellular Biology, vol.23,(10),2003,pp 3427-3441
2006Rat models of myocardial infarction. Pathogenetic insights and clinical relevance.Bhindi, Ravinay; Lowe, Harry; McMahon, Aisling; Witting, Paul; Khachigian, Levon M.; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteRat models of myocardial infarction. Pathogenetic insights and clinical relevance., Thrombosis and Haemostasis, vol.96,(5),2006,pp 602-610
2011Recent developments in drug-eluting stents.Bhindi, Ravinay; Khachigian, Levon M.; Yue, Li; Concord Clinical School: ANZAC Research InstituteRecent developments in drug-eluting stents., Journal of Molecular Medicine (online), vol.89, 6, 2011,pp 545-553
2013Regulation of vascular leak and recovery from ischaemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27Gamble, Jennifer; Kench, James; Li, Jia; Lichtenstein, Ilana; Lu, Ying; McCaughan, Geoffrey William; Moses, Joshua; Shackel, Nicholas; Ting, Ka Ka; Tran, Nham; Vadas, Mathew; Young, Jennifer; Dunn, Louise; Goodall, Gregory; Gregory, Philip; Hahn, Christopher; Khachigian, Levon M.; Moller, Thorleif; Ng, Martin K.C; Prado-Lourenco, Leonel; Tsykin, Anna; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Chemistry; Schl Information Technologies; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteRegulation of vascular leak and recovery from ischaemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27, Blood, vol.122, 16, 2013,pp 2911-2919
2006The role of c-jun in PDTC-sensitive flow-dependent restenosis after angioplasty and stenting.Murrell, Melanie; Ward, Michael; Khachigian, Levon M.; Medicine; Northern Clinical School: MedicineThe role of c-jun in PDTC-sensitive flow-dependent restenosis after angioplasty and stenting., Atherosclerosis, vol.Dec 26,(Epub ahead of print),2006,pp N/A-N/A
2013Selective Inhibition of the Master Regulator Transcription Factor Egr-1 With Catalytic Oligonucleotides Reduces Myocardial Injury and Improves Left Ventricular Systolic Function in a Preclinical Model of Myocardial InfarctionBhindi, Ravinay; Figtree, Gemma Alexandra; Grieve, Stuart; Hunyor, Stephen; Lay, William; Mazhar, Jawad; Rayner, Benjamin; Sabaretnam, Tharani; Shang, Ping; Weaver, James; Witting, Paul; Khachigian, Levon M.; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Central Clinical School: Heart Research Institute; Medicine; Northern Clinical School: Kolling Institute; Anaesthesia; School of Medical Sciences: PathologySelective Inhibition of the Master Regulator Transcription Factor Egr-1 With Catalytic Oligonucleotides Reduces Myocardial Injury and Improves Left Ventricular Systolic Function in a Preclinical Model of Myocardial Infarction, Journal of the American Heart Association, vol.2, 4, 2013,pp 1-9
2012Succinobucol induces apoptosis in vascular smooth muscle cellsDennis, Joanne; Maghzal, Ghassan; Midwinter, Robyn; Stocker, Roland; Wu, Ben; Belikova, Natalia; Cai, Hong; Dong, Lan-Feng; Kagan, Valerian; Kapralov, Alexandr; Khachigian, Levon M.; Neuzil, Jiri; Tyurina, Yulia; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Central Clinical School: Heart Research InstituteSuccinobucol induces apoptosis in vascular smooth muscle cells, Free Radical Biology and Medicine, vol.52, 5, 2012,pp 871-879