Browsing by Author Kelly, Darren J.

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Showing results 1 to 12 of 12
Issue DateTitleAuthor(s)Citation
2007Advanced glycation end products decrease mesangial cell MMP-7: A role in matrix accumulation in diabetic nephropathy?McLennan, Susan; Yue, Dennis; Dy, Veronica; Gilbert, Richard E.; Kelly, Darren J.; Langham, R; Schache, M; Waltham, M; Central Clinical School: Medicine; Central Clinical School: MedicineAdvanced glycation end products decrease mesangial cell MMP-7: A role in matrix accumulation in diabetic nephropathy?, Kidney International (2005), vol.72,(4),2007,pp 481-488
2007The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1.Chen, Xin-Ming; Pollock, Carol; Qi, Weier; Twigg, Stephen; Gilbert, Richard E.; Kelly, Darren J.; Zhang, Yuan; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Molecular Medicine (Kolling I); Central Clinical School: MedicineThe differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1., Nephrology, vol.12,(3),2007,pp 267-274
2006Heart failure and nephropathy: Catastrophic and interrelated complications of diabetes.Pollock, Carol; Connelly, Kim; Gilbert, Richard E.; Kelly, Darren J.; Krum, Henry; Northern Clinical School: MedicineHeart failure and nephropathy: Catastrophic and interrelated complications of diabetes., Clinical Journal of the American Society of Nephrology, vol.1,(2),2006,pp 193-208
2009High glucose induced endothelial cell growth inhibition is associated with an increase in TGF-{beta}(1) secretion and inhibition of Ras prenylation via suppression of the mevalonate pathwayChen, Xin-Ming; Field, Michael; Mather, Amanda; McGinn, Catherine Mary; Pollock, Carol; Sumual, Siska; Kelly, Darren J.; Mangiafico, S; Zhang, Yuan; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Clinical Schools; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteHigh glucose induced endothelial cell growth inhibition is associated with an increase in TGF-{beta}(1) secretion and inhibition of Ras prenylation via suppression of the mevalonate pathway, The International Journal of Biochemistry and Cell Biology, vol.41, 3, 2009,pp 561-569
2007High glucose induces macrophage inflammatory protein-3{alpha} in renal proximal tubule cells via a transforming growth factor-{beta}1 dependent mechanismChen, Xin-Ming; Holian, John; Mreich, Ellein; Pollock, Carol; Qi, Weier; Gilbert, Richard E.; Kelly, Darren J.; Zhang, Yuan; Northern Clinical School: Medicine; Clinical Schools; Medicine; Northern Clinical School: Medicine; Northern Clinical School: Molecular Medicine (Kolling I)High glucose induces macrophage inflammatory protein-3{alpha} in renal proximal tubule cells via a transforming growth factor-{beta}1 dependent mechanism, Nephrology Dialysis Transplantation (2005), vol.22,(11),2007,pp 3147-3153
2005High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule.Pollock, Carol; Poronnik, Philip; Stevens, Veronica; Gilbert, Richard E.; Kelly, Darren J.; Saad, Sonia; Wassef, Lesley; Northern Clinical School: Medicine; Medicine Faculty Office; Northern Clinical School: MedicineHigh glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule., Kidney International (2005), vol.68,(3),2005,pp 985-997
2007High Glucose-Induced Thioredoxin-Interacting Protein in Renal Proximal Tubule Cells Is Independent of Transforming Growth Factor-{beta}1Chen, Xin-Ming; Pollock, Carol; Qi, Weier; Gilbert, Richard E.; Kelly, Darren J.; Schache, Maria; Waltham, Mark; Zhang, Yuan; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteHigh Glucose-Induced Thioredoxin-Interacting Protein in Renal Proximal Tubule Cells Is Independent of Transforming Growth Factor-{beta}1, The American Journal of Pathology: cellular and molecular biology of disease, vol.171,(3),2007,pp 744-754
2008Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycemic controlPollock, Carol; Christensen, P. K.; Cox, A. J.; Gilbert, Richard E.; Gow, R. M.; Kelly, Darren J.; Langham, R; Parving, H. H.; Qi, Weier; Thai, K.; Zhang, Yuan; Northern Clinical School: MedicineIncreased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycemic control, Diabetologia: clinical and experimental diabetes and metabolism, vol.51, 4, 2008,pp 668-674
2003Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathyPollock, Carol; Qi, Weier; Gilbert, Richard E.; Kelly, Darren J.; Mifsud, Sally; Wilkinson-Berka, Jennifer L.; Zhang, Yuan; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteIntervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy, The Nephron Journals, vol.95,(4),2003,pp 83-91
2008The Role of Kruppel-like factor 6 in Transforming Growth Factor-Beta-1-induced Epithelial-Mesenchymal Transition of Proximal Tubule CellsChen, Xin-Ming; Holian, John; Mreich, Ellein; Pollock, Carol; Qi, Weier; Kelly, Darren J.; Zhang, Yuan; Northern Clinical School: Medicine; Clinical Schools; Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteThe Role of Kruppel-like factor 6 in Transforming Growth Factor-Beta-1-induced Epithelial-Mesenchymal Transition of Proximal Tubule Cells, American Journal of Physiology: Renal Physiology, vol.295,(5),2008,pp F1388-F1396
2011The roles of Kruppel-like factor 6 and peroxisome proliferator-activated receptor-γ in the regulation of macrophage inflammatory protein-3α at early onset of diabetesChen, Xin-Ming; Holian, John; Pollock, Carol; Qi, Weier; Kelly, Darren J.; Tan, Christina Y R; Northern Clinical School: Medicine; Clinical Schools; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteThe roles of Kruppel-like factor 6 and peroxisome proliferator-activated receptor-γ in the regulation of macrophage inflammatory protein-3α at early onset of diabetes, The International Journal of Biochemistry & Cell Biology, vol.43, 3, 2011,pp 383-392
2016Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathwayBraet, Filip; Chen, Xin-Ming; Cheng, Delfine; Huang, Chunling; Park, Jin-Sung; Pollock, Carol; Sue, Carolyn; Gill, Anthony; Kelly, Darren J.; Tan, Christina Y R; Zhang, Yuan; School of Medical Sciences: Anatomy & Histology; Northern Clinical School: Medicine; School of Medical Sciences: Bosch Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: MedicineThioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway, Scientific Reports, vol.6, N/A, 2016,pp 1-13