Browsing by Author Kalinowski, Danuta

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Issue DateTitleAuthor(s)Citation
20092-Acetylpyridine Thiosemicarbazones are Potent Iron Chelators and Antiproliferative Agents: Redox Activity, Iron Complexation and Characterization of their Antitumor ActivityKalinowski, Danuta; Lovejoy, David; Richardson, Desi; Richardson, Vera; Bernhardt, Paul V.; Islam, Mohammad; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute2-Acetylpyridine Thiosemicarbazones are Potent Iron Chelators and Antiproliferative Agents: Redox Activity, Iron Complexation and Characterization of their Antitumor Activity, Journal of Medicinal Chemistry, vol.52,(5),2009,pp 1459-1470
2013Alkyl Substituted 2'-Benzoylpyridine Thiosemicarbazone Chelators with Potent and Selective Anti-Neoplastic Activity: Novel Ligands that Limit Methemoglobin FormationGutierrez, Elaine; Jansson, Jan (Patric); Kalinowski, Danuta; Richardson, Desi (Des); Stefani, Christian; Bernhardt, Paul V; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyAlkyl Substituted 2'-Benzoylpyridine Thiosemicarbazone Chelators with Potent and Selective Anti-Neoplastic Activity: Novel Ligands that Limit Methemoglobin Formation, Journal of Medicinal Chemistry, vol.56, 1, 2013,pp 357-370
2010Amphiphilic hyper-branched co-polymer nanoparticles for the controlled delivery of anti-tumor agentsKalinowski, Danuta; Lovejoy, David; Richardson, Desi; Miao, Qinghua; Nie, Guangjun; Wang, Tiewei; Wang, Zhi; Wu, Yan; Xu, Dongxue; Xu, Li; Zhao, Yuliang; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyAmphiphilic hyper-branched co-polymer nanoparticles for the controlled delivery of anti-tumor agents, Biomaterials, vol.31, 28,pp 7364-7375
2013Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: Effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron poolKalinowski, Danuta; Lane, Darius; Lovejoy, David; Richardson, Desi (Des); Adenuga, Babafemi B; Kurantsin-Mills, Joseph; Kwagyan, John; Walcourt, Asikiya; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyAnti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: Effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron pool, Journal of Inorganic Biochemistry, vol.129, N/A, 2013,pp 43-51
2009Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agentsJansson, Jan; Kalinowski, Danuta; Lau, S; Lovejoy, David; Richardson, Desi; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyCancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents, B B A - Bioenergetics, vol.1790,(7),2009,pp 702-717
2015Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in diseaseBae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineCellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease, Biochimica et Biophysica Acta. General Subjects, vol.1853, 5, 2015,pp 1130-1144
2013Cellular Uptake of the Antitumor Agent Dp44mT Occurs via a Carrier/Receptor-Mediated MechanismKalinowski, Danuta; Menezes, Sharleen; Merlot, Angelica; Pantarat, Namfon; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Bosch Institute; Western Clinical School: Westmead Millennium Institute; School of Medical Sciences: Pathology; MedicineCellular Uptake of the Antitumor Agent Dp44mT Occurs via a Carrier/Receptor-Mediated Mechanism, Molecular Pharmacology, vol.84, 6, 2013,pp 911-924
2006Chelators at the cancer coalface: desferrioxamine to triapine and beyond.Kalinowski, Danuta; Lovejoy, David; Richardson, Desi; Wong, Jacky; Yu, Yu; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyChelators at the cancer coalface: desferrioxamine to triapine and beyond., Clinical Cancer Research, vol.12,(23),2006,pp 6876-6883
2010Comparison of Clinically Used and Experimental Iron Chelators for Protection against Oxidative Stress-Induced Cellular InjuryKalinowski, Danuta; Richardson, Desi (Des); Bendova, Petra; Haskova, Pavlina; Jirkovsky, Eduard; Kovarikova, Petra; Mackova, Eliska; Popelova, Olga; Simunek, Tomas; Sterba, Martin; Vavrova, Anna; Vavrova, Katerina; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyComparison of Clinically Used and Experimental Iron Chelators for Protection against Oxidative Stress-Induced Cellular Injury, Chemical Research in Toxicology, vol.23, 6, 2010,pp 1105-1114
2010Conjugates of Desferrioxamine B (DFOB) with Derivatives of Adamantane or with Orally Available Chelators as Potential Agents for Treating Iron Overload.Codd, Rachel; Groebler, Ludwig; Kalinowski, Danuta; Liu, Joe; Obando Gutierrez, Daniel; Richardson, Desi; Schipanski, Liam; Witting, Paul; School of Medical Sciences: Pharmacology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pharmacology; Chemistry; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PathologyConjugates of Desferrioxamine B (DFOB) with Derivatives of Adamantane or with Orally Available Chelators as Potential Agents for Treating Iron Overload., Journal of Medicinal Chemistry, vol.53, 3,pp 1370-1382
2013Deferasirox (ICL670A) effectively inhibits oesophageal cancer growth in vitro and in vivoJansson, Jan (Patric); Kalinowski, Danuta; Lovejoy, David; Lui, Goldie; Obeidy, Peyman; Richardson, Desi (Des); Alderson, D; Bedford, M; Chadwick, C; Ford, Samuel; Iqbal, TH; Nichols, L; Tselepis, Chris; Tucker, O; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; Central Clinical School: Pathology; School of Medical Sciences: PathologyDeferasirox (ICL670A) effectively inhibits oesophageal cancer growth in vitro and in vivo, British Journal of Pharmacology, vol.168, 6, 2013,pp 1316-1328
2007Design, Synthesis, and Characterization of New Iron Chelators with Anti-Proliferative Activity: Structure-Activity Relationships of Novel Thiohydrazone AnaloguesKalinowski, Danuta; Richardson, Desi; Bernhardt, Paul V.; Sharpe, Philip C; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDesign, Synthesis, and Characterization of New Iron Chelators with Anti-Proliferative Activity: Structure-Activity Relationships of Novel Thiohydrazone Analogues, Journal of Medicinal Chemistry, vol.50,(24),2007,pp 6212-6225
2007Design, Synthesis, and Characterization of Novel Iron Chelators: Structure-Activity Relationships of the 2-Benzoylpyridine Thiosemicarbazone Series and Their 3-Nitrobenzoyl Analogues as Potent Antitumor AgentsKalinowski, Danuta; Lovejoy, David; Richardson, Desi; Yu, Yu; Bernhardt, Paul V; Islam, Mohammad; Kumar, Naresh; Liao, Yi-Tyng; Sharpe, Philip C; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDesign, Synthesis, and Characterization of Novel Iron Chelators: Structure-Activity Relationships of the 2-Benzoylpyridine Thiosemicarbazone Series and Their 3-Nitrobenzoyl Analogues as Potent Antitumor Agents, Journal of Medicinal Chemistry, vol.50,(15),2007,pp 3716-3729
2007Development and validation of HPLC-DAD methods for the analysis of two novel iron chelators with potent anti-cancer activity.Kalinowski, Danuta; Richardson, Desi; Klimes, Jiri; Kovaríková, Petra; Mrkvicková, Zlata; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDevelopment and validation of HPLC-DAD methods for the analysis of two novel iron chelators with potent anti-cancer activity., Journal of Pharmaceutical and Biomedical Analysis, vol.43,(4),2007,pp 1343-1351
2010Development of an LC-MS/MS method for analysis of interconvertible Z/E isomers of the novel anticancer agent, Bp4eTKalinowski, Danuta; Richardson, Desi; Klimes, Jiri; Kovarikova, Petra; Stariat, Jan; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDevelopment of an LC-MS/MS method for analysis of interconvertible Z/E isomers of the novel anticancer agent, Bp4eT, Analytical and Bioanalytical Chemistry, vol.397, 1,pp 161-171
2006Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity.Kalinowski, Danuta; Lovejoy, David; Richardson, Desi; Bernhardt, Paul V.; Islam, Mohammad; Senaratne, Dakshita; Sharpe, Philip C.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity., Journal of Medicinal Chemistry, vol.49,(22),2006,pp 6510-6521
2014Effect of the piperazine unit and metal-binding site position on the solubility and anti-proliferative activity of ruthenium(II)- and osmium(II)- arene complexes of isomeric indolo[3,2-c]quinoline-piperazine hybridsKalinowski, Danuta; Richardson, Desi (Des); Arion, Vladimir B; Bauer, Theresa J; Filak, Lukas K; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyEffect of the piperazine unit and metal-binding site position on the solubility and anti-proliferative activity of ruthenium(II)- and osmium(II)- arene complexes of isomeric indolo[3,2-c]quinoline-piperazine hybrids, Inorganic Chemistry, vol.53, 13, 2014,pp 6934-6943
2014Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transitionKalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Mills, Thomas; Richardson, Desi (Des); Saleh Moussa, Rayan; Shafie, Nurul; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyExpanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transition, Biochimica et Biophysica Acta-Reviews on Cancer, vol.1845, 2, 2014,pp 166-181
2014Exploring the anti-cancer activity of novel thiosemicarbazones generated through the combination of retro-fragments: dissection of critical structure-activity relationshipsKalinowski, Danuta; Rasko, Nathalie; Richardson, Desi (Des); Golab, Jakul; Małecki, Jan G; Mrozek-Wilczkiewicz, Anna; Muchowicz, Angelika; Musiol, Robert; Polanski, Jaroslaw; Potuckova, Eliska; Ratuszna, Alicja; Sajewicz, Mieczysław; Serda, Maciej; Simunek, Tomas; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PathologyExploring the anti-cancer activity of novel thiosemicarbazones generated through the combination of retro-fragments: dissection of critical structure-activity relationships, PloS One, vol.9, 10, 2014,pp 1-15
2016Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxiaChiang, Shannon; Huang, Michael; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyFrataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia, Clinical Science, vol.130, 11, 2016,pp 853-870