Browsing by Author Johns, Terrance G

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Showing results 1 to 7 of 7
Issue DateTitleAuthor(s)Citation
2017Cyclin-dependent kinase 7 is a therapeutic target in high-grade gliomaO'Neill, Geraldine; Day, Bryan W.; Ensbey, K. S.; Gough, D. J.; Greenall, S. A.; Johns, Terrance G; Lim, Y C; McDonald, Kerrie L; Mitchell, Camilla; Stringer, Brett W.; Wilding, A L; Childrens Hospital Westmead: Paediatrics & Child HealthCyclin-dependent kinase 7 is a therapeutic target in high-grade glioma, Oncogenesis, vol.6, 5, 2017,pp 1-13
2015Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2Akerfeldt, Mia; Chircop (nee Fabbro), Megan; Gurgis, Fadi; Munoz, Lenka; Wong, Chin; Adams, Seray; Guillemin, Gilles J.; Heng, Benjamin; Johns, Terrance G; Chemistry; Childrens Medical Research Institute (CMRI); School of Medical Sciences: Pharmacology; School of Medical Sciences: Pathology; Children's Hospital Westmead: Childrens Medical Research InsCytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2, Cell Death Discovery, vol.1, N/A, 2015,pp 1-11
2017Development and Biological Evaluation of a Photoactivatable Small Molecule Microtubule-Targeting AgentAbbassi, Ramzi; Dobber, Alexander; Munoz, Lenka; Phoa, Athena; Abadleh, M; Day, Bryan W.; Johns, Terrance G; Peifer, C; Stringer, Brett W.; School of Medical Sciences: Pharmacology; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: PharmacologyDevelopment and Biological Evaluation of a Photoactivatable Small Molecule Microtubule-Targeting Agent, ACS Medicinal Chemistry Letters, vol.8, 4, 2017,pp 395-400
2012Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancerPavlakis, Nick; Azad, Arun; Chong, Geoff; Dobrovic, Alexander; Fluck, Kate; Gebski, Val; Johns, Terrance G; Mariadason, John M; Price, Timothy; Salemi, R; Scott, Andrew M; Skrinos, Effie; Tebbutt, Niall; Weickhardt, Andrew J; Northern Clinical School: MedicineDual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer, Journal of Clinical Oncology, vol.30, 13, 2012,pp 1505-1512
2015DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implicationsAbbassi, Ramzi; Kassiou, Michael; Munoz, Lenka; Johns, Terrance G; School of Medical Sciences: Pharmacology; Medical Imaging and Radiation Sciences; School of Medical Sciences: PharmacologyDYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications, Pharmacology & Therapeutics, vol.151, N/A, 2015,pp 87-98
2015Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signallingAkerfeldt, Mia; Brown, Stephen; Chircop (nee Fabbro), Megan; Döbber, Alexander; Gurgis, Fadi; Kassiou, Michael; Munoz, Lenka; Phoa, Athena; Renn, Christian; Wong, Chin; Day, Bryan W.; Johns, Terrance G; Peifer, Christian; Stringer, Brett W.; Chemistry; School of Medical Sciences: Pharmacology; Childrens Medical Research Institute (CMRI); School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; Medical Imaging and Radiation Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; Children's Hospital Westmead: Childrens Medical Research InsPharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling, Biochemical Pharmacology, vol.98, 4, 2015,pp 587-601
2017Structural optimization and pharmacological evaluation of inhibitors targeting dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) and CDC-like kinases (CLK) inglioblastomaAbbassi, Ramzi; Font Sadurni, Josep; Hoque, Monira; Kassiou, Michael; Munoz, Lenka; Phoa, Athena; Reekie, Tristan Andrew; Ryan, Renae; Zhou, Qingdi; Day, Bryan W.; Johns, Terrance G; Stringer, Brett W.; School of Medical Sciences: Pharmacology; School of Molecular Bioscience (SMB); Pharmacy; Chemistry; School of Medical Sciences: Pathology; School of Medical Sciences: Pharmacology; Medical Imaging and Radiation Sciences; School of Medical Sciences: Pharmacology; ChemistryStructural optimization and pharmacological evaluation of inhibitors targeting dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) and CDC-like kinases (CLK) inglioblastoma, Journal of Medicinal Chemistry, vol.60, 5, 2017,pp 2052-2070