Browsing by Author Jin, Lei

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Showing results 1 to 16 of 16
Issue DateTitleAuthor(s)Citation
2014Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; James, Wilmott; McArthur, Grant A.; Tummino, Peter J; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteControl of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151, Pigment Cell & Melanoma Research, vol.27, 6, 2014,pp 1126-1137
2013Cotargeting histone deactylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3Hersey, Peter; Atmadibrata, B; Chi, MN; Croft, A.; Farelly, M; Guo, Su T; Jiang, CC; Jin, Lei; Lai, F; Liu, T; Norman, J; Tseng, Hsin-Yi; Wang, CY; Zhang, XD; Northern Clinical School: SurgeryCotargeting histone deactylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3, Cell Death and Disease, vol.4, N/A, 2013,pp 1-13
2014The Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma CellsGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteThe Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma Cells, Journal of Investigative Dermatology, vol.134, 11, 2014,pp 1523-1747
2012Histone Deacetylases (HDACs) as Mediators of Resistance to Apoptosis in Melanoma and as Targets for Combination Therapy with Selective BRAF InhibitorsGallagher, Stuart; Hersey, Peter; Jin, Lei; Mijatov, Branka; Lai, Fritz; Zhang, Xu Dong; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium InstituteHistone Deacetylases (HDACs) as Mediators of Resistance to Apoptosis in Melanoma and as Targets for Combination Therapy with Selective BRAF Inhibitors, Advances in Pharmacology, vol.65, N/A, 2012,pp 27-43
2015INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomasScolyer, Richard; Wilmott, James; Chi, Meng Na; Croft, Amanda; et al, Various; Guo, Sutang; Guo, X Y; Jin, Lei; Liu, Tao; Liu, Xiao Ying; Tseng, Hsin-Yi; Wang, ChunYan; Yan, Xu Guang; Central Clinical School: Pathology; Central Clinical School: SurgeryINPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas, Oncotarget, vol.6, 37, 2015,pp 39891-39907
2011MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanomaHersey, Peter; Scolyer, Richard; Wilmott, James; Chu, Ping; Han, Chuan Chun; Hu, Wang Lai; Jiang, Chen Chen; Jin, Lei; Thorne, R F; Wang, Jia X; Wu, Mian; Zhang, Lin Jie; Zhang, X. D.; Northern Clinical School: Surgery; Central Clinical School: Pathology; School of Medical Sciences: PathologyMicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma, Proceedings of the National Academy of Sciences (PNAS), vol.108, 38, 2011,pp 15840-15845
2013MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancerJin, Lei; Feng, Y; Guo, Sutang; Guo, X Y; Jiang, Chen Chen; Li, Y P; Thorne, Rick; Tseng, Hsin-Yi; Wang, ChunYan; Wang, F H; Wang, G P; Yang, R H; Zhang, Xu Dong; Northern Clinical School: Kolling InstituteMicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer, Oncogene, vol.32, 15, 2013,pp 1910-1920
2014Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cellsScolyer, Richard; Wilmott, James; Guo, Su T; Jiang, Chen Chen; Jin, Lei; Lai, Fritz; Liu, Xiao Ying; Liu, Yi Lun; Luan, Qi; Tseng, Hsin-Yi; Yan, Xu Guang; Zhang, Xu Dong; Central Clinical School: Pathology; Central Clinical School: SurgeryNoxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells, Oncotarget, vol.5, 22, 2014,pp 11237-11251
2014Oncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum StressBoyd, Suzanah; Hersey, Peter; Rizos, Helen; Croft, Amanda; Guo, Su T; Jiang, Chen Chen; Jin, Lei; Lai, Fritz; Tay, Kwang Hong; Tseng, Hsin-Yi; Zhang, Xu Dong; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteOncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum Stress, Journal of Investigative Dermatology, vol.134, 2, 2014,pp 488-497
2014Oncogenic suppression of PHLPP1 in human melanomaScolyer, Richard; Wilmott, James; Dong, Li; Guo, Sutang; Jiang, CC; Jiang, Chen Chen; Jin, Lei; Tseng, Hsin-Yi; Wang, ChunYan; Yan, Xu Guang; Yosufi, B; Central Clinical School: Pathology; Central Clinical School: SurgeryOncogenic suppression of PHLPP1 in human melanoma, Oncogene, vol.33, 39, 2014,pp 4756-4766
2013PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanomaHersey, Peter; Jin, Lei; Rizos, Helen; Scolyer, Richard; Wilmott, James; Yosufi, Benafsha; de Bock, C E; Dong, Li; et al, Various; Guo, Sutang; Hu, Wang Lai; Liu, Tao; Tay, Kwang Hong; Thorne, Rick; Tseng, Hsin-Yi; Yan, Xu Guang; Ye, Yan; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: PathologyPI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma, Nature Communications, vol.4, Article number1508, 2013,pp 1-15
2015Poor sleep during the periconceptional period increases risk for neural tube defects in offspringRaynes-Greenow, Camille; Jin, Lei; Li, Zhiwen; Ren, Aiguo; Ye, Rongwei; Zhang, Le; School of Public Health: Public HealthPoor sleep during the periconceptional period increases risk for neural tube defects in offspring, Birth Defects Research. Part A: Clinical and Molecular Teratology, vol.103, 9, 2015,pp 780-786
2014Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanomaHersey, Peter; Jin, Lei; Croft, A.; Guo, Sutang; Jiang, Chen Chen; Tseng, Hsin-Yi; Zhang, XD; Northern Clinical School: Surgery; Northern Clinical School: Kolling InstituteRepression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma, Oncogene, vol.33, 20, 2014,pp 2577-2588
2015RIP1 Kinase Is an Oncogenic Driver in MelanomaScolyer, Richard; Wilmott, James; Croft, Amanda; Guo, Sutang; Jiang, Chen Chen; Jin, Lei; Lai, Fritz; Liu, Xiao Ying; Tseng, Hsin-Yi; Wang, ChunYan; Yan, Xu Guang; Zhang, Xu Dong; Central Clinical School: Pathology; Central Clinical School: SurgeryRIP1 Kinase Is an Oncogenic Driver in Melanoma, Cancer Research, vol.75, 8, 2015,pp 1736-1748
2017Skp2-mediated stabilization of MTH1 promotes survival of melanoma cells upon oxidative stressScolyer, Richard; Wilmott, James; Feng, Yu Chen; Jin, Lei; La, Ting; Liu, Guang Zhi; Thorne, Rick F.; Wang, Jia Yu; Yan, Xu Guang; Yari, Hamed; Zhang, Xu Dong; Central Clinical School: Pathology; Central Clinical School: SurgerySkp2-mediated stabilization of MTH1 promotes survival of melanoma cells upon oxidative stress, Cancer Research, vol.77, 22, 2017,pp 6226-6239
2012Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stressHersey, Peter; Jin, Lei; Guo, Sutang; Jiang, Chen Chen; Liu, Tao; Tay, Kwang Hong; Thorne, Rick; Tseng, Hsin-Yi; Verrills, Nicole M.; Ye, Yan; Zhang, Xu Dong; Northern Clinical School: Surgery; Northern Clinical School: Kolling InstituteSuppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress, Cell Death and Disease, vol.3, N/A, 2012,pp 1-11