Browsing by Author Humphrey, Sean

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Showing results 1 to 11 of 11
Issue DateTitleAuthor(s)Citation
2017The amino acid transporter SLC1A3 is plasma membrane-localised in adipocytes and its activity is insensitive to insulinBurchfield, James; Cater, Rosemary; Fazakerley, Daniel; Humphrey, Sean; James, David; Krycer, James; Naghiloo, Sheyda; Ryan, Renae; Thomas, Kristen; Vandenberg, Robert; School of Life and Environmental Sciences (SOLES); School of Medical Sciences: Pharmacology; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Molecular Bioscience (SMB); School of Medical Sciences: Pharmacology; School of Life and Environmental Sciences (SOLES); School of Medical Sciences: PharmacologyThe amino acid transporter SLC1A3 is plasma membrane-localised in adipocytes and its activity is insensitive to insulin, FEBS Letters, vol.591, 2, 2017,pp 322-330
2013Dynamic adipocyte phosphoproteome reveals that akt directly regulates mTORC2Yang, Pengyi; Yang, Yee (Jean); Fazakerley, Daniel; Humphrey, Sean; James, David; Stockli, Jacqueline; Yang, Guang; Schl Information Technologies; Mathematics & StatisticsDynamic adipocyte phosphoproteome reveals that akt directly regulates mTORC2, Cell Metabolism, vol.17, 6, 2013,pp 1009-1020
2017Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose MetabolismCooney, Gregory; Domanova, Westa; Fazakerley, Daniel; Healy, Marin; Humphrey, Sean; James, David; Krycer, James; Parker, Benjamin Leo; Quek, Lake-Ee; Scalzo, Richard; et al, Various; Hirayama, Akiyoshi; Hodson, Mark P.; Hoehn, Kyle L; Ikeda, Satsuki; Ohno, Satoshi; Shoji, Futaba; Suzuki, Kumi; Turner, Nigel; Yugi, Katsuyuki; School of Medical Sciences: School of Medical Sciences; Physics; School of Life and Environmental Sciences (SOLES); School of Molecular Bioscience (SMB); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); Mathematics & Statistics; Engineering & IT AdministrationDynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism, Cell Reports, vol.21, 12, 2017,pp 3536-3547
2015Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK SubstratesBurchfield, James; Chaudhuri, Rima; Fazakerley, Daniel; Hoffman, Nolan; Holliday, Mira; James, David; Parker, Benjamin Leo; Stoeckli, Jacqueline; Fisher-Wellman, Kelsey H; Humphrey, Sean; Jensen, Thomas E.; Jothi, Raja; Kiens, Bente; Kleinert, Maximillian; Richter, Erik A; Trefely, Sophie; Wojtaszewski, Jorgen F P; Yang, Pengyi; Molecular Bioscience; Molecular Bioscience; Molecular Bioscience; Molecular Bioscience; Biological Sciences; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceGlobal Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates, Cell Metabolism, vol.22, 5, 2015,pp 922-935
2016Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in AdipocytesChaudhuri, Rima; Cooney, Gregory; Humphrey, Sean; James, David; Minard, Annabel; Parker, Benjamin Leo; Stoeckli, Jacqueline; Wong, Martin Kin Lok; Yang, Jean Yee Hwa; Coster, Adelle; Laybutt, D. Ross; Tan, Shi-Xiong; Molecular Bioscience; School of Medical Sciences: School of Medical Sciences; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); Molecular Bioscience; School of Life and Environmental Sciences (SOLES); Physics; Mathematics & StatisticsHyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes, Journal of Biological Chemistry, vol.291, 49, 2016,pp 25629-25640
2016Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in AdipocytesChaudhuri, Rima; Cooney, Gregory; Humphrey, Sean; James, David; Minard, Annabel; Parker, Benjamin Leo; Stoeckli, Jacqueline; Wong, Martin Kin Lok; Yang, Jean Yee Hwa; Coster, Adelle; Laybutt, D. Ross; Tan, Shi-Xiong; Molecular Bioscience; School of Medical Sciences: School of Medical Sciences; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); Molecular Bioscience; School of Life and Environmental Sciences (SOLES); Physics; Mathematics & StatisticsHyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes, The Journal of Biological Chemistry, vol.291, 49, 2016,pp 25629-25640
2016KinasePA: Phosphoproteomics data annotation using hypothesis driven kinase perturbation analysisGhazanfar, Shila; Humphrey, Sean; James, David; Yang, Jean Yee Hwa; Yang, Pengyi; Jothi, Raja; Patrick, Ellis; Mathematics & Statistics; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); Mathematics & Statistics; Mathematics & StatisticsKinasePA: Phosphoproteomics data annotation using hypothesis driven kinase perturbation analysis, Proteomics, vol.16, 13, 2016,pp 1868-1871
2016mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in AdipocytesDomanova, Westa; Fazakerley, Daniel; Humphrey, Sean; James, David; Minard, Annabel; Parker, Benjamin Leo; Stoeckli, Jacqueline; Yang, Pengyi; Jothi, Raja; Tan, Shi-Xiong; Physics; Molecular Bioscience; School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); Molecular Bioscience; School of Life and Environmental Sciences (SOLES); Mathematics & StatisticsmTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes, Cell Reports, vol.17, 1, 2016,pp 29-36
2016mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in AdipocytesDomanova, Westa; Fazakerley, Daniel; Humphrey, Sean; James, David; Minard, Annabel; Parker, Benjamin Leo; Stoeckli, Jacqueline; Yang, Pengyi; Jothi, Raja; Tan, Shi-Xiong; Physics; School of Molecular Bioscience (SMB); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Life and Environmental Sciences (SOLES); School of Molecular Bioscience (SMB); School of Life and Environmental Sciences (SOLES); Mathematics & StatisticsmTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes, Cell Reports, vol.17, 1, 2016,pp 29-36
2011Quantitative Proteomic Analysis of the Adipocyte Plasma MembraneJames, David; Buckley, Michael; Burchfield, James; Davey, Jonathon; Guilhaus, Michael; Humphrey, Sean; Kanazawa, Hiroshi; Kistler, Carol; La-Borde, Penelope; Larance, Mark; Lawrence, Robert; Parton, Robert G.; Prior, Matthew; Soul, Jamie; School of Life and Environmental Sciences (SOLES)Quantitative Proteomic Analysis of the Adipocyte Plasma Membrane, Journal of Proteome Research, vol.10, 11, 2011,pp 4970-4982
2012Re-Fraction: A machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomicsYang, Pengyi; Yang, Yee (Jean); Fazakerley, Daniel; Humphrey, Sean; James, David; Prior, Matthew; Yang, Guang; Schl Information Technologies; Mathematics & StatisticsRe-Fraction: A machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomics, Journal of Proteome Research, vol.11, 5, 2012,pp 3035-3045