Browsing by Author Huang, Michael

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Issue DateTitleAuthor(s)Citation
2013Biochemistry of cardiomyopathy in the mitochondrial disease Friedreich's ataxiaHuang, Michael; Lane, Darius; Richardson, Desi (Des); Sivagurunathan, Sutharshani; Ting, Samantha; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Physiology; Central Clinical School: PathologyBiochemistry of cardiomyopathy in the mitochondrial disease Friedreich's ataxia, The Biochemical Journal, vol.453, 3, 2013,pp 321-336
2015Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in diseaseBae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineCellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease, Biochimica et Biophysica Acta. General Subjects, vol.1853, 5, 2015,pp 1130-1144
2009Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutantBecker, Erika; Huang, Michael; Richardson, Desi (Des); Suryo Rahmanto, Yohan; Whitnall, Megan; Ponka, Prem; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical SciencesElucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant, Proceedings of the National Academy of Sciences (PNAS) of the United States of America, vol.106, 38, 2009,pp 16381-16386
2014Fixing frataxin: "ironing out" the metabolic defect in friedreich's ataxiaAnzovino, Amy; Huang, Michael; Lane, Darius John Rowland; Richardson, Desi (Des); School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyFixing frataxin: "ironing out" the metabolic defect in friedreich's ataxia, British Journal of Pharmacology, vol.171, 8, 2014,pp 2174-2190
2016Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxiaChiang, Shannon; Huang, Michael; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyFrataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia, Clinical Science, vol.130, 11, 2016,pp 853-870
2013Hepcidin Bound to α2-Macroglobulin Reduces Ferroportin-1 Expression and Enhances Its Activity at Reducing Serum Iron LevelsHuang, Michael; Richardson, Desi (Des); Suryo Rahmanto, Yohan; Ponka, Prem; Sari, Marie-Agnès; Vyoral, Daniel; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyHepcidin Bound to α2-Macroglobulin Reduces Ferroportin-1 Expression and Enhances Its Activity at Reducing Serum Iron Levels, The Journal of Biological Chemistry, vol.288, 35, 2013,pp 25450-25465
2013Hepcidin, show some self-control! How the hormone of iron metabolism regulates its own expressionHuang, Michael; Lane, Darius; Richardson, Desi (Des); School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyHepcidin, show some self-control! How the hormone of iron metabolism regulates its own expression, The Biochemical Journal, vol.452, 2, 2013,pp e3-e5
2009Hepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in bloodBecker, Erika; Huang, Michael; Kuchel, Philip; Richardson, Desi (Des); Suryo Rahmanto, Yohan; Sutak, Robert; Vyoral, Daniel; Halada, Petr; Hrdy, Ivan; Kuzelova, Katerina; Peslova, Gabriela; Petrak, Jiri; Ponka, Prem; Soe-Lin, Shan; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Molecular Bioscience; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical SciencesHepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in blood, Blood, vol.113, 24, 2009,pp 6225-6236
2012Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxiaHuang, Michael; Lok, Hiu; Richardson, Desi (Des); Saletta, Federica; Suryo Rahmanto, Yohan; Whitnall, Megan; Fleming, Adam; Gutierrez, Lucia; Lazaro, Francisco; Mikhael, Marc R.; Ponka, Prem; ST Pierre, T. G.; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical SciencesIdentification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia, Proceedings of the National Academy of Sciences (PNAS), vol.109, 50, 2012,pp 20590-20595
2010The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich's ataxia.Becker, Erika; Huang, Michael; Richardson, Desi; Suryo Rahmanto, Yohan; Whitnall, Megan; Ponka, Prem; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical SciencesThe ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich's ataxia., Journal of Molecular Medicine, vol.88, 4,pp 2010-323
2018Mitochondrial dysfunction in the neuro-degenerative and cardio-degenerative disease, Friedreich's ataxiaChiang, Shannon; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Richardson, Desi (Des); Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMitochondrial dysfunction in the neuro-degenerative and cardio-degenerative disease, Friedreich's ataxia, Neurochemistry International, vol.117, N/A, 2018,pp 35-48
2010Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.Becker, Erika; Huang, Michael; Lane, Darius; Richardson, Desi; Suryo Rahmanto, Yohan; Ponka, Prem; Sheftel, Alex; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol., Proceedings of the National Academy of Sciences, vol.107, 24,pp 10775-10782
2017Molecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia: An Impaired Nrf2 Response Mediated via Upregulation of Keap1 and Activation of the Gsk3(beta) AxisAnzovino, Amy; Brown, Bronwyn; Chiang, Shannon; Hawkins, Clare; Huang, Michael; Richardson, Desi (Des); School of Medical Sciences: Pathology; Central Clinical School: Heart Research Institute; Central Clinical School: Pathology; Central Clinical School: Heart Research Institute; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMolecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia: An Impaired Nrf2 Response Mediated via Upregulation of Keap1 and Activation of the Gsk3(beta) Axis, American Journal of Pathology, vol.187, 12, 2017,pp 2858-2875
2013Molecular and Functional Alterations in a Mouse Cardiac Model of Friedreich Ataxia: Activation of the Integrated Stress Response, eIF2a Phosphorylation, and the Induction of Downstream TargetsAustin, Christopher; Huang, Michael; Jansson, Jan (Patric); Kelly, Matthew; Richardson, Desi (Des); Semsarian, Chris; Sivagurunathan, Sutharshani; Ting, Samantha; Zhang, Daohai; Chemistry; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Anaesthesia; School of Medical Sciences: Pathology; Central Clinical School: Centenary Institute; School of Medical Sciences: Physiology; Central Clinical School: Pathology; School of Medical Sciences: PathologyMolecular and Functional Alterations in a Mouse Cardiac Model of Friedreich Ataxia: Activation of the Integrated Stress Response, eIF2a Phosphorylation, and the Induction of Downstream Targets, The American Journal of Pathology: cellular and molecular biology of disease, vol.183, 3, 2013,pp 745-757
2015The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targetsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Jin, Runsen; Liu, Wensheng; Peng, Zhihai; Wang, Puxiongzhi; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targets, Oncotarget, vol.6, 34, 2015,pp 35522-35541
2015The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targetsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Jin, Runsen; Liu, Wensheng; Peng, Zhihai; Wang, Puxiongzhi; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: New therapeutic targets, Oncotarget, vol.6, 34, 2015,pp 35522-35541
2014Potent Anti-Mycobacterial Activity of the Pyridoxal Isonicotinoyl Hydrazone Analogue, 2-Pyridylcarboxaldehyde Isonicotinoyl Hydrazone: A Lipophilic Transport Vehicle for Isonicotinic Acid HydrazideEllis, Samantha; Huang, Michael; Kalinowski, Danuta; Leotta, Lisa; Richardson, Desi (Des); Sintchenko, Vitali; Triccas, James; Jelfs, Peter; Central Clinical School: Medicine; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Western Clinical School: Medicine (Westmead); Central Clinical School: MedicinePotent Anti-Mycobacterial Activity of the Pyridoxal Isonicotinoyl Hydrazone Analogue, 2-Pyridylcarboxaldehyde Isonicotinoyl Hydrazone: A Lipophilic Transport Vehicle for Isonicotinic Acid Hydrazide, Molecular Pharmacology, vol.85, 2, 2014,pp 269-278
2015Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cellsDoddareddy, Munikumar; Fordham, Ashleigh; Hibbs, David; Huang, Michael; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Ong, Jennifer; Pantarat, Namfon; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Bosch Institute; Pharmacy; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; Pharmacy; Western Clinical School: Westmead Institute for Medical Res; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyPotentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells, Oncotarget, vol.6, 12, 2015,pp 10374-10398
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874