Browsing by Author Holz, Lauren

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Issue DateTitleAuthor(s)Citation
2010CD8+ T cell tolerance following antigen recognition on hepatocytes.Bertolino, Patrick; Bowen, David; Holz, Lauren; Le Couteur, David; Warren, Alessandra; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteCD8+ T cell tolerance following antigen recognition on hepatocytes., Journal of Autoimmunity, vol.34, 1,pp 15-22
2005Early intrahepatic antigen-specific retention of naïve CD8+ T cells is predominantly ICAM-1/LFA-1 dependent in mice.Bertolino, Patrick; Bowen, David; Holz, Lauren; McCaughan, Geoffrey; Eulenburg, Katharina; Ghani, Saeed; Hamann, Alf; Hogg, Nancy; Klugewitz, Katja; Schrage, Arnhild; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteEarly intrahepatic antigen-specific retention of naïve CD8+ T cells is predominantly ICAM-1/LFA-1 dependent in mice., Hepatology, vol.42,(5),2005,pp 1063-1071
2016Effector T cell function rather than survival determines extent and duration of hepatitis in miceBenseler, Volker; Bertolino, Patrick; Bowen, David; English, Kieran; Holz, Lauren; McCaughan, Geoffrey William; McGuffog, Claire; Vo, Michelle; Wong, Yik Chun; Azuma, Miyuki; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteEffector T cell function rather than survival determines extent and duration of hepatitis in mice, Journal of Hepatology, vol.64, 6, 2016,pp 1327-1338
2011Hepatocyte entry leads to degradation of autoreactive CD8 T cellsBenseler, Volker; Bertolino, Patrick; Bowen, David; Breen, Eamon; Holz, Lauren; Le Couteur, David; McCaughan, Geoffrey William; McGuffog, Claire; Tay, Szun; Vo, Michelle; Warren, Alessandra; Allison, Anthony C; Schlitt, Hans Juergen; Van Rooijen, Nico; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research InstituteHepatocyte entry leads to degradation of autoreactive CD8 T cells, Proceedings of the National Academy of Sciences of the United States of America (PNAS), vol.108, 40, 2011,pp 16735-16740
2006Immune-mediated hepatitis drives low-level fusion between hepatocytes and adult bone marrow cells.Bertolino, Patrick; Bowen, David; Dahlke, Marc-Hendrik; Holz, Lauren; McCaughan, Geoffrey; Schlitt, Hans; Loi, Roberto; Piso, Pompiliu; Popp, Felix C.; Warren, Alessandra; Weiss, Daniel J.; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Clinical SchoolsImmune-mediated hepatitis drives low-level fusion between hepatocytes and adult bone marrow cells., Journal of hepatology, vol.44,(2),2006,pp 334-341
2008Intrahepatic Murine CD8 T-Cell Activation Associates With a Distinct Phenotype Leading to Bim-Dependent DeathBenseler, Volker; Bertolino, Patrick; Bishop, George (Alex); Bowen, David; d'Avigdor, William; Holz, Lauren; McCaughan, Geoffrey; Bouillet, Philippe; O'Reilly, Lorraine; Strasser, Andreas; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteIntrahepatic Murine CD8 T-Cell Activation Associates With a Distinct Phenotype Leading to Bim-Dependent Death, Gastroenterology, vol.135,(3),2008,pp 989-997
2010Mechanisms of T cell death in the liver: to Bim or not to Bim?Bertolino, Patrick; Bowen, David; Holz, Lauren; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteMechanisms of T cell death in the liver: to Bim or not to Bim?, Digestive Diseases, vol.28, 1,pp 14-24
2012Naive CD8 T cell activation by liver bone marrow-derived cells leads to a "neglected" IL-2(low) Bim(high) phenotype, poor CTL function and cell deathBenseler, Volker; Bertolino, Patrick; Bowen, David; Holz, Lauren; McCaughan, Geoffrey; McGuffog, Claire; Vo, Michelle; Van Rooijen, Nico; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteNaive CD8 T cell activation by liver bone marrow-derived cells leads to a "neglected" IL-2(low) Bim(high) phenotype, poor CTL function and cell death, Journal of Hepatology, vol.57, 4, 2012,pp 830-836
2005Phenotype of CD8+ T cells activated in the liverBenseler, Volker; Bertolino, Patrick; Holz, Lauren; McCaughan, Geoffrey; Gengos, M.; Newtown, R.; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstitutePhenotype of CD8+ T cells activated in the liver, Tissue Antigens, vol.66,(5),2005,pp 444 (Abstract 279)-444
2017The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injuryBertolino, Patrick; Chowdhury, Sumaiya; Cordoba, Shaun; Evans, Kathryn; Gall, Margaret; Gorrell, Mark; Holz, Lauren; Jolly, Christopher; Levy, Miriam; McCaughan, Geoffrey William; Polak, Natasa; Vieira de Ribeiro, Ana; Wang, Xin (Maggie); Yao, Tsun-Wen; Yu, Ming Tse Denise; Zheng, Yuan; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Molecular Bioscience (SMB)The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury, Immunology and Cell Biology, vol.95, 5, 2017,pp 443-453
2004The Site Of Primary T Cell Activation Is A Determinant Of The Balance Between Intrahepatic Tolerance And Immunity.Bertolino, Patrick; Bowen, David; Davis, Tracey; Holz, Lauren; McCaughan, Geoffrey; Zen, Monica; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Research PrecinctsThe Site Of Primary T Cell Activation Is A Determinant Of The Balance Between Intrahepatic Tolerance And Immunity., Journal of Clinical Investigation, vol.114,(5),2004,pp 701-712