Browsing by Author Gunatilake, Dilini

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Issue DateTitleAuthor(s)Citation
2015Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signalingDe Paoli-Iseppi, Ricardo; Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Strbenac, Dario; Tiffen, Jessamy; Wilmott, James; Yang, Jean Yee Hwa; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Mathematics & Statistics; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Mathematics & StatisticsCombining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling, Oncotarget, vol.6, 25, 2015,pp 21507-21521
2014Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; James, Wilmott; McArthur, Grant A.; Tummino, Peter J; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteControl of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151, Pigment Cell & Melanoma Research, vol.27, 6, 2014,pp 1126-1137
2014The Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma CellsGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteThe Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma Cells, Journal of Investigative Dermatology, vol.134, 11, 2014,pp 1523-1747
2018HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanomaBeaumont, Kimberley; Ferguson, Peter; Gallagher, Stuart; Gunatilake, Dilini; Haass, Nikolas; Heinemann, Anja; Hersey, Peter; Madore, Jason; Rizos, Helen; Sharp, Danae; Tiffen, Jessamy; Weninger, Wolfgang; Wilmott, James; Central Clinical School: Centenary Institute; Medicine; Westmead Clinical School: Medicine; Northern Clinical School: Kolling Institute; Central Clinical School: Centenary Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryHDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma, International Journal of Cancer, vol.142, 9, 2018,pp 1926-1937
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genesGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Mann, Graham; Pupo, Gulietta; Strbenac, Dario; Tiffen, Jessamy; Yang, Jean Yee Hwa; Cullinane, Carleen; Dutton-Regester, Ken; Filli[, Fabian V.; Hayward, Nicholas; McArthur, Grant A.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Mathematics & Statistics; Central Clinical School: Centenary Institute; Mathematics & StatisticsTargeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes, Oncotarget, vol.6, 29, 2015,pp 27023-27036