Browsing by Author Gu, Baijun (Ben)

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Showing results 1 to 16 of 16
Issue DateTitleAuthor(s)Citation
2005A 50 intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1–2% of the Caucasian populationDao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Skarratt, K; Sluyter, Ronald; Wiley, James; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineA 50 intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1–2% of the Caucasian population, FEBS Letters (2005), vol.579,(12),2005,pp 2675-2678
2004An Arg307 To Gln Polymorphism Within The Atp-Binding Site Causes Loss Of Function Of The Human P2X7 Receptor.Barden, Julian; Dao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Shemon, Anne; Skarratt, K; Sluyter, Ronald; Wiley, James; Clarke, Alison L; Petrou, Steven; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineAn Arg307 To Gln Polymorphism Within The Atp-Binding Site Causes Loss Of Function Of The Human P2X7 Receptor., Journal of Biological Chemistry, vol.279,(30),2004,pp 31287-31295
2009Genetics of the P2X7 receptor and human diseaseFuller, Stephen; Gu, Baijun (Ben); Skarratt, K; Stokes, Leanne; Wiley, James; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineGenetics of the P2X7 receptor and human disease, Purinergic Signalling, vol.5,(2),2009,pp 257-262
2003An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptorBarden, Julian; Dao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Li, Changping; Shemon, Anne; Sluyter, Ronald; Wiley, James; Petrou, Steven; Smart, Megan L; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineAn Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor, Journal of Biological Chemistry, vol.278,(19),2003,pp 17108-17113
2011A Loss-of-Function Polymorphism in the Human P2X4 Receptor Is Associated With Increased Pulse PressureGu, Baijun (Ben); Skarratt, Kristen; Stokes, Leanne; Wiley, James; Cromer, Brett; Ellis, Justine; Harrap, Stephen B.; Scurrah, Katrina Jacqueline; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineA Loss-of-Function Polymorphism in the Human P2X4 Receptor Is Associated With Increased Pulse Pressure, Hypertension, vol.58, 6, 2011,pp 1086-1092
2010The P2X(7)-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATPGu, Baijun (Ben); Jursik, Claudia; Saunders, Bernadette; Wiley, James; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Central Clinical School: Centenary Institute; Nepean Clinical School: MedicineThe P2X(7)-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATP, Blood, vol.115, 8,pp 1621-1631
2011P2X7 Is a Scavenger Receptor for Apoptotic Cells in the Absence of Its Ligand, Extracellular ATP.Gu, Baijun (Ben); Saunders, Bernadette; Wiley, James; Petrou, Steven; Nepean Clinical School: Medicine; Central Clinical School: Centenary Institute; Nepean Clinical School: MedicineP2X7 Is a Scavenger Receptor for Apoptotic Cells in the Absence of Its Ligand, Extracellular ATP., Journal of Immunology, vol.187, 5, 2011,pp 2365-2375
2015P2X7 is an archaic scavenger receptor recognizing apoptotic neuroblasts in early human neurogenesisAllen, David; Chan-Ling, Tailoi; Eamegdool, Steven; Gu, Baijun (Ben); Lovelace, Michael; Weible, Michael; Wiley, James; School of Medical Sciences: Physiology; School of Medical Sciences: Anatomy & Histology; Molecular Bioscience; Nepean Clinical School: Medicine; School of Medical Sciences: Anatomy & HistologyP2X7 is an archaic scavenger receptor recognizing apoptotic neuroblasts in early human neurogenesis, Receptors & Clinical Investigation, vol.2, N/A, 2015,pp 1-8
2003P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal regionGu, Baijun (Ben); Wiley, James; Cromer, Brett; Panchal, Rekha G.; Petrou, Steven; Smart, Megan L; Williams, David A.; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineP2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region, Journal of Biological Chemistry, vol.278,(10),2003,pp 8853-8860
2015P2X7 Receptors mediate Innate phagocytosis by Human Neural Precursor Cells and NeuroblastsAllen, David; Chan-Ling, Tailoi; Eamegdool, Steven; Gu, Baijun (Ben); Lovelace, Michael; Weible, Michael; Wiley, James; School of Medical Sciences: Physiology; School of Medical Sciences: Anatomy & Histology; Molecular Bioscience; Nepean Clinical School: Medicine; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Anatomy & HistologyP2X7 Receptors mediate Innate phagocytosis by Human Neural Precursor Cells and Neuroblasts, Stem Cells, vol.33, 2, 2015,pp 526-541
2002Point mutations confer loss of ATP-induced human P2X7 receptor functionBarden, Julian; Gu, Baijun (Ben); Wiley, James; Worthington, Rebecca; Petrou, Steven; Smart, M. L.; Williams, David A.; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Anatomy & HistologyPoint mutations confer loss of ATP-induced human P2X7 receptor function, FEBS Letters, vol.512,(1-3),2002,pp 43-46
2007A quantitative method for routine measurement of cell surface P2X(7) receptor function in leucocyte subsets by two-colour time-resolved flow cytometryFuller, Stephen; Georgiou, Jennifer; Gu, Baijun (Ben); Jursik, Claudia; Sluyter, Ronald; Wiley, James; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineA quantitative method for routine measurement of cell surface P2X(7) receptor function in leucocyte subsets by two-colour time-resolved flow cytometry, Journal of Immunological Methods (2005), vol.325,(1-2),2007,pp 67-77
2006Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X(7) receptor.Gu, Baijun (Ben); Wiley, James; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineRapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X(7) receptor., Blood 2005, vol.107,(12),2006,pp 4946-4953
2003Specific detection of non-functional human P2X7 receptors in HEK293 cells and B-lymphocytesBarden, Julian; Gu, Baijun (Ben); Sluyter, Ronald; Wiley, James; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineSpecific detection of non-functional human P2X7 receptors in HEK293 cells and B-lymphocytes, FEBS Letters, vol.538,(1-3),2003,pp 159-162
2006A Thr(357) to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X(7) function and impairs ATP-induced mycobacterial killing by macrophages.Britton, Warwick; Dao-Ung, L; Fernando, Suran; Fuller, Stephen; Gu, Baijun (Ben); Saunders, Bernadette; Shemon, Anne; Skarratt, K; Sluyter, Ronald; Wiley, James; Clarke, Alison L; Petrou, Steven; Tan, Khai See; Central Clinical School: Centenary Institute; Nepean Clinical School: Medicine; Central Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Central Clinical School: Centenary Institute; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineA Thr(357) to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X(7) function and impairs ATP-induced mycobacterial killing by macrophages., Journal of Biological Chemistry, vol.281,(4),2006,pp 2079-2086
2010Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1{beta} secretion.Fuller, Stephen; Gu, Baijun (Ben); Skarratt, Kristen; Sluyter, Ronald; Stokes, Leanne; Wiley, James; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineTwo haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1{beta} secretion., The F A S E B Journal, vol.24, 8,pp 2916-2927