Browsing by Author Gowrishankar, Kavitha

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Issue DateTitleAuthor(s)Citation
2012Absence of Distinguishing Senescence Traits in Human Melanocytic NeviBecker, Therese; Gowrishankar, Kavitha; Kefford, Richard (Rick); Rizos, Helen; Scolyer, Richard; Scurr, Lyndee; Thompson, John; Tran, Sieu; Desilva, Chitra; Haferkamp, Sebastian; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Pathology; Western Clinical School: Medicine (Westmead); Central Clinical School: Surgery; Western Clinical School: Medicine (Westmead)Absence of Distinguishing Senescence Traits in Human Melanocytic Nevi, The Journal of Investigative Dermatology, vol.132, 9, 2012,pp 2226-2234
2012Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK InhibitionBecker, Therese; Gowrishankar, Kavitha; Kefford, Richard (Rick); Pupo, Gulietta; Rizos, Helen; Snoyman, Stephanie; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteAcquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition, The Journal of Investigative Dermatology, vol.132, 7, 2012,pp 1850-1859
2013Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in MelanomaBecker, Therese; Carlino, Matteo; Gowrishankar, Kavitha; Kefford, Richard (Rick); Long, Georgina; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Snoyman, Stephanie; Saunders, Catherine; Zhang, Xu Dong; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteAntiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma, Molecular Cancer Therapeutics, vol.12, 7, 2013,pp 1332-1342
2010Characterization of the host immune response in human Ganglia after herpes zosterAbendroth, Allison; Cunningham, Anthony (Tony); Gowrishankar, Kavitha; Slobedman, Barry; Steain, Megan; Blumbergs, Peter C.; Rodriguez, Michael; Central Clinical School: Medicine; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Characterization of the host immune response in human Ganglia after herpes zoster, Journal of Virology, vol.84, 17,pp 8861-8870
2015Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signalingDe Paoli-Iseppi, Ricardo; Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Strbenac, Dario; Tiffen, Jessamy; Wilmott, James; Yang, Jean Yee Hwa; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Mathematics & Statistics; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Mathematics & StatisticsCombining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling, Oncotarget, vol.6, 25, 2015,pp 21507-21521
2014Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; James, Wilmott; McArthur, Grant A.; Tummino, Peter J; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteControl of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151, Pigment Cell & Melanoma Research, vol.27, 6, 2014,pp 1126-1137
2014Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanomaCarlino, Matteo; Fung, C.; Gowrishankar, Kavitha; Hersey, Peter; Kefford, Richard (Rick); Long, Georgina; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Snoyman, Stephanie; Todd, Jason; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteDifferential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma, Molecular Oncology, vol.8, 3, 2014,pp 544-554
2014The Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma CellsGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteThe Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma Cells, Journal of Investigative Dermatology, vol.134, 11, 2014,pp 1523-1747
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2014Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factorBecker, Therese; Boyd, Suzanah; Gowrishankar, Kavitha; Kefford, Richard (Rick); Mann, Graham; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Snoyman, Stephanie; Scolyer, Richard A; Zhang, XD; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteMutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor, Oncogene, vol.33, 9, 2014,pp 1158-1166
2013Oncogenic B-RAF(V600E) Signaling Induces the T-Box3 Transcriptional Repressor to Repress E-Cadherin and Enhance Melanoma Cell InvasionBecker, Therese; Boyd, Suzanah; Gowrishankar, Kavitha; Kefford, Richard (Rick); Mann, Graham; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tran, Sieu; Goding, Colin; Scolyer, Richard A; Shaw, Heather M; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Oncogenic B-RAF(V600E) Signaling Induces the T-Box3 Transcriptional Repressor to Repress E-Cadherin and Enhance Melanoma Cell Invasion, The Journal of Investigative Dermatology, vol.133, 5, 2013,pp 1269-1277
2015Pembrolizumab joins the anti-PD-1 armamentarium in the treatment of melanomaGowrishankar, Kavitha; Hersey, Peter; Western Clinical School: Medicine (Westmead); Northern Clinical School: SurgeryPembrolizumab joins the anti-PD-1 armamentarium in the treatment of melanoma, Future Oncology, vol.11, 1, 2015,pp 133-140
2007Productive varicella-zoster virus infection of cultured intact human ganglia.Abendroth, Allison; Boadle, Ross; Cunningham, Anthony (Tony); Gowrishankar, Kavitha; Miranda Saksena, Monica; Slobedman, Barry; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteProductive varicella-zoster virus infection of cultured intact human ganglia., Journal of Virology, vol.81,(12),2007,pp 6752-6756
2015Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genesGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Mann, Graham; Pupo, Gulietta; Strbenac, Dario; Tiffen, Jessamy; Yang, Jean Yee Hwa; Cullinane, Carleen; Dutton-Regester, Ken; Filli[, Fabian V.; Hayward, Nicholas; McArthur, Grant A.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Mathematics & Statistics; Central Clinical School: Centenary Institute; Mathematics & StatisticsTargeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes, Oncotarget, vol.6, 29, 2015,pp 27023-27036
2011Upregulation of CXCL10 in Human Dorsal Root Ganglia during Experimental and Natural Varicella-Zoster Virus InfectionAbendroth, Allison; Gowrishankar, Kavitha; Slobedman, Barry; Steain, Megan; Rodriguez, Michael; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Upregulation of CXCL10 in Human Dorsal Root Ganglia during Experimental and Natural Varicella-Zoster Virus Infection, Journal of Virology, vol.85, 1, 2011,pp 626-631