Browsing by Author Goetz, Jurgen

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Issue DateTitleAuthor(s)Citation
2010Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunctionGoetz, Jurgen; Ittner, Lars; Lim, Yun-An; Baysang, Ginette; Eckert, Anne; Guilhaus, Michael; Meier, Fides; Poljak, Anne; Raftery, Mark J.; Rhein, Virginie; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteAbeta and human amylin share a common toxicity pathway via mitochondrial dysfunction, Proteomics, vol.10, 8,pp 1621-1633
2007Abeta treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entryGoetz, Jurgen; Hoerndli, Frederic; Papassotiropoulos, Andreas; Pelech, Steven; School of Medical Sciences: School of Medical SciencesAbeta treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry, European Journal of Neuroscience, vol.26,(1),2007,pp 60-72
2006Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation.Goetz, Jurgen; Ittner, Lars; Ke, Yazi; Lim, Yem; Hemmings, Brian A.; Schild, Andreas; Schmidt, Karsten; Central Clinical School: Brain & Mind Research Institute; School of Medical Sciences: School of Medical Sciences; Central Clinical School: Brain & Mind Research Institute; School of Medical Sciences: PathologyAltered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation., International Journal of Developmental Neuroscience, vol.24,(7),2006,pp 437-443
2011Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylationGoetz, Jurgen; Bakota, L.; Brandt, R.; Fath, Thomas; Hundelt, M.; Jordan, J.; Lewejohann, L.; Monyer, H.; Oesterwind, K; Sachser, N.; Schultz, C.; Selle, K.; von Engelhardt, J.; School of Medical Sciences: Brain & Mind Research InstituteAltered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation, Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology, vol.32, 6, 2011,pp 991-1006
2006Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice.Goetz, Jurgen; Ittner, Lars; Schild, Andreas; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical SciencesAltered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice., Biochemical and Biophysical Research Communications (2005), vol.343,(4),2006,pp 1171-1178
2006Alzheimer's disease and frontotemporal dementia: prospects of a tailored therapy?Goetz, Jurgen; Ittner, Lars; Schonrock, Nicole; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical SciencesAlzheimer's disease and frontotemporal dementia: prospects of a tailored therapy?, Medical Journal of Australia 2005, vol.185,(7),2006,pp 381-384
2009Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.Goetz, Jurgen; Ittner, Lars; Wiesner, Andreas; Baysang, Ginette; Bluethmann, H; Brandt, Ulrich; Czech, Christian; Drose, Stefan; Eckert, Anne; Meier, Fides; Ozmen, Laurence; Rhein, Virginie; Savaskan, Egemen; Song, Xiaomin; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteAmyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice., Proceedings of the National Academy of Sciences, vol.106,(47),2009,pp 20057-20062
2011Amyloid‑β and Tau — A Toxic Pas De Deux in Alzheimer’s DiseaseGoetz, Jurgen; Ittner, Lars; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteAmyloid‑β and Tau — A Toxic Pas De Deux in Alzheimer’s Disease, Nature Reviews. Neuroscience, vol.12, 2, 2011,pp 67-72
2010Analysis of the cholinergic pathology in the P301L tau transgenic pR5 model of tauopathyGoetz, Jurgen; Bista, P; Kohler, Chong; Schroder, H; School of Medical Sciences: Brain & Mind Research InstituteAnalysis of the cholinergic pathology in the P301L tau transgenic pR5 model of tauopathy, Brain Research, vol.1347, N/A,pp 111-124
2008Animal models of Alzheimer's disease and frontotemporal dementiaGoetz, Jurgen; Ittner, Lars; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical SciencesAnimal models of Alzheimer's disease and frontotemporal dementia, Nature Reviews. Neuroscience, vol.9,(7),2008,pp 532-544
2010Animal models reveal role for tau phosphorylation in human diseaseGladbach, Amadeus; Goetz, Jurgen; Ittner, Lars; Van Eersel, Janet; David, Della C; Pennanen, Luis; Schild, Andreas; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: PharmacologyAnimal models reveal role for tau phosphorylation in human disease, Biochimica et Biophysica Acta-Molecular Basis of Disease, vol.1802, 10,pp 860-871
2008Antiviral CD8 T cells recognize borna disease virus antigen transgenically expressed in either neurons or astrocytesGoetz, Jurgen; Baur, Karen; Hausmann, Jurgen; Pagenstecher, Axel; Rauer, Mathias; Richter, Kirsten; Staeheli, Peter; School of Medical Sciences: School of Medical SciencesAntiviral CD8 T cells recognize borna disease virus antigen transgenically expressed in either neurons or astrocytes, Journal of Virology, vol.82,(6),2008,pp 3099-3108
2006beta-Amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes.David, Della; Goetz, Jurgen; Ittner, Lars; Nergenau, Denise; Gehrig, Peter; Halliday, Glenda M.; Shepherd, Claire; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical Sciencesbeta-Amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes., Proteomics, vol.6,(24),2006,pp 6566-6577
2009Common features between diabetes mellitus and Alzheimer's diseaseGoetz, Jurgen; Ittner, Lars; Lim, Yun-An; Central Clinical School: Brain & Mind Research Institute; School of Medical Sciences: School of Medical Sciences; Central Clinical School: Brain & Mind Research InstituteCommon features between diabetes mellitus and Alzheimer's disease, CMLS-Cellular and Molecular Life Sciences, vol.66,(8),2009,pp 1321-1325
2010Convergence of amyloid-beta and tau pathologies on mitochondria in vivoGoetz, Jurgen; Eckert, Anne; Rhein, Virginie; Schulz, Kathrin; School of Medical Sciences: Brain & Mind Research InstituteConvergence of amyloid-beta and tau pathologies on mitochondria in vivo, Cellular and Molecular Neurobiology, vol.41, 2-3,pp 107-114
2007A decade of tau transgenic animal models and beyondBokhari, Yaa; Deters, Natasha; Doldissen, Amy; Goetz, Jurgen; Ittner, Lars; Ke, Yazi; Schonrock, Nicole; Wiesner, Andreas; School of Medical Sciences: Anatomy & Histology; Molecular & Microbial Bioscien; Central Clinical School: Brain & Mind Research Institute; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical Sciences; Medicine; School of Medical Sciences: School of Medical Sciences; Central Clinical School: Brain & Mind Research InstituteA decade of tau transgenic animal models and beyond, Brain Pathology, vol.17,(1),2007,pp 91-103
2005Different tau epitopes define Abeta42-mediated tau insolubility.Goetz, Jurgen; Pennanen, Luis; School of Medical Sciences: School of Medical SciencesDifferent tau epitopes define Abeta42-mediated tau insolubility., Biochemical and Biophysical Research Communications (2005), vol.337,(4),2005,pp 1097-101
2007Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils.Goetz, Jurgen; Brodhun, Michael; Fandrich, Marcus; Friedrich, Ralf; Gellermann, Gerald; Habicht, Gernot; Halbhuber, Karl-Jurgen; Haupt, Christian; Horn, Uwe; Hortschansky, Peter; Meinhardt, Jessica; Rocken, Christoph; Sachse, Carsten; Wieligmann, Karin; School of Medical Sciences: School of Medical SciencesDirected selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils., National Academy of Sciences. Proceedings, vol.104,(49),2007,pp 19232-19237
2008Divergent phosphorylation pattern of tau in P301L tau transgenic miceDeters, Natasha; Goetz, Jurgen; Ittner, Lars; Molecular & Microbial Bioscien; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical SciencesDivergent phosphorylation pattern of tau in P301L tau transgenic mice, European Journal of Neuroscience, vol.28,(1),2008,pp 137-147
2006Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?Goetz, Jurgen; Ittner, Lars; Kins, Stefan; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical SciencesDo axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?, Journal of Neurochemistry, vol.98,(4),2006,pp 993-1006