Browsing by Author Gladbach, Amadeus

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Issue DateTitleAuthor(s)Citation
2010Animal models reveal role for tau phosphorylation in human diseaseGladbach, Amadeus; Goetz, Jurgen; Ittner, Lars; Van Eersel, Janet; David, Della C; Pennanen, Luis; Schild, Andreas; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: PharmacologyAnimal models reveal role for tau phosphorylation in human disease, Biochimica et Biophysica Acta-Molecular Basis of Disease, vol.1802, 10,pp 860-871
2011Cytoplasmic Accumulation and Aggregation of TDP-43 upon Proteasome Inhibition in Cultured Neurons.Bi, M; Götz, Jürgen; Gladbach, Amadeus; Ittner, Lars; Ke, Yazi; Kril, Jillian J; Van Eersel, Janet; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; Central Clinical School: Pathology; School of Medical Sciences: PharmacologyCytoplasmic Accumulation and Aggregation of TDP-43 upon Proteasome Inhibition in Cultured Neurons., PLoS One, vol.6, 7, 2011,pp 1-13
2010Dendritic Function of Tau Mediates Amyloid-beta Toxicity in Alzheimer's Disease Mouse ModelsBi, Mian; Chieng, Billy Chin Hak; Christie, MacDonald; Delerue, Fabien; Gladbach, Amadeus; Goetz, Jurgen Martin; Ittner, Lars; Ke, Yazi; Napier, Ian; Van Eersel, Janet; Wolfing, Heidrun; Eckert, Anne; Hardeman, Edna; Staufenbiel, Matthias; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Pharmacology; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Brain and Mind CentreDendritic Function of Tau Mediates Amyloid-beta Toxicity in Alzheimer's Disease Mouse Models, Cell, vol.142, 3, 2010,pp 387-397
2015Early-onset axonal pathology in a novel P301S-Tau transgenic mouse model of frontotemporal lobar degenerationIttner, Lars; Kril, Jillian; Sutherland, Greg; Abramowski, Dorothee; Chan, Chesed Kai-Xin; Gladbach, Amadeus; Halliday, G; Hodges, John R.; Ong, Weiyi; Przybyla, Magdalena; Staufenbiel, Matthias; Stefanoska, Kristie; Stevens, Claire; van Eersel, Janet; School of Medical Sciences: Brain and Mind Centre; Central Clinical School: Medicine; School of Medical Sciences: PathologyEarly-onset axonal pathology in a novel P301S-Tau transgenic mouse model of frontotemporal lobar degeneration, Neuropathology and Applied Neurobiology, vol.41, 7, 2015,pp 906-925
2014ERK inhibition with PD184161 mitigates brain damage in a mouse model of strokeBi, Mian; Gladbach, Amadeus; Ittner, Lars; Ke, Yazi; Van Eersel, Janet; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: PharmacologyERK inhibition with PD184161 mitigates brain damage in a mouse model of stroke, Journal of Neural Transmission, vol.121, 5, 2014,pp 543-547
2009Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease.Delerue, Fabien; Gladbach, Amadeus; Goetz, Jurgen; Ittner, Lars; Yazi, K; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteExperimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease., P L o S One, vol.4,(11),2009,pp e7917 - 1-e7917 - 7
2017The polyphenol altenusin inhibits in vitro fibrillization of tau and reduces induced tau pathology in primary neuronsKassiou, Michael; Chua, Sook Wern; Cornejo, Alberto; Cueto, Mercedes; Gladbach, Amadeus; Ittner, Lars; Lewis, Lev; Macmillan, Alexander; Stevens, Claire; Vaca, Inmaculada; van Eersel, Janet; Whan, Renee M.; ChemistryThe polyphenol altenusin inhibits in vitro fibrillization of tau and reduces induced tau pathology in primary neurons, ACS Chemical Neuroscience, vol.8, 4, 2017,pp 743-751
2015Short‑term suppression of A315T mutant human TDP‑43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD‑TDP and ALSHaass, Nikolas; Kiernan, Matthew; Bi, Mian; et al, Various; Gladbach, Amadeus; Hoven, Julia van der; Hummel, Annika van; Ippati, Stefania; Ke, Yazi D.; Kruger, Sarah; Lee, Wei S.; Stevens, Claire; Volkerling, Alexander; Central Clinical School: Centenary Institute; Central Clinical School: MedicineShort‑term suppression of A315T mutant human TDP‑43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD‑TDP and ALS, Acta Neuropathologica, vol.130, 5, 2015,pp 661-678
2016Site-specific phosphorylation of tau inhibits amyloid-b toxicity in Alzheimer's miceKril, Jillian; Mackay, Joel; Silva, Ana Paula; Suh, Lisa; Sutherland, Greg; Bertz, Josefine; Bi, Mian; Chua, Sook Wern; et al, Various; Gladbach, Amadeus; Ippati, Stefania; Ittner, Arne; Macmillan, Alexander; Przybyla, Magdalena; Stevens, Claire; van der Hoven, Julia; van Hummel, Annika; Volkerling, Alexander; Central Clinical School: Medicine; School of Molecular Bioscience (SMB); School of Molecular Bioscience (SMB); School of Medical Sciences: Pathology; School of Medical Sciences: PathologySite-specific phosphorylation of tau inhibits amyloid-b toxicity in Alzheimer's mice, Science, vol.354, 6314, 2016,pp 904-908