Browsing by Author Gell, David

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Issue DateTitleAuthor(s)Citation
2010AHSP (α-haemoglobin-stabilizing protein) stabilizes apo-α-haemoglobin in a partially folded stateGell, David; Kumar, Kaavya; Mackay, Joel; Dickson, Claire; Weiss, Mitchell J; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceAHSP (α-haemoglobin-stabilizing protein) stabilizes apo-α-haemoglobin in a partially folded state, Biochemical Journal, vol.432, 2,pp 275-282
2002Biophysical characterization of the a-globin binding protein a-hemoglobin stabilizing proteinEaton, Sally; Gell, David; Mackay, Joel; Kong, Yi; Weiss, Mitchell J; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienBiophysical characterization of the a-globin binding protein a-hemoglobin stabilizing protein, Journal of Biological Chemistry, vol.277,(43),2002,pp 40602-40609
2002Characterization of the conserved interaction between GATA and FOG family proteinsCrossley, Paul (Merlin); Gell, David; Kowalski, Kasper; Liew, Chu; Mackay, Joel; Matthews, Jacqueline; School of Molecular Bioscience; School of Molecular Bioscience; Biochemistry; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceCharacterization of the conserved interaction between GATA and FOG family proteins, Journal of Biological Chemistry, vol.277, 38,pp 35720-35729
2009A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobinBendak, Katerina; Gell, David; Mackay, Joel; Feng, Liang; Gow, Andrew; Jeffrey, Philip; Shi, Yigong; Weiss, Mitchell J; Zhou, Suiping; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceA cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin, Journal of Biological Chemistry, vol.284, 43, 2009,pp 29462-29469
2012The detection and quantitation of protein oligomerizationGell, David; Grant, Richard; Mackay, Joel; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceThe detection and quantitation of protein oligomerization in Protein Dimerization and Oligomerization in Biology, Springer Science + Business Media, 2012, pp. 19-41
2013Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin CGell, David; Liew, Chu; Mackay, Joel; Brown, Louise J; Cordina, Nicole; Fajer, Piotr; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceEffects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin C, Biochemistry, vol.52, 11, 2013,pp 1950-1962
2003Engineering a protein scaffold from a PhD fingerCrossley, Paul (Merlin); Gell, David; Kwan, Ann; Mackay, Joel; Matthews, Jacqueline; Verger, Alexis; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienEngineering a protein scaffold from a PhD finger, Structure, vol.11,(7),2003,pp 803-813
2007An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesisGell, David; Mackay, Joel; Abdulmalik, Osheiza; Choi, John K; Dore, Louis C; Gow, Andrew J; Katein, Anne M; Kong, Yi; Weiss, Mitchell J; Yu, Xiang; Zhou, Suiping; Molecular & Microbial Bioscien; Molecular & Microbial BioscienAn erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis, Journal of Clinical Investigation, vol.117,(7),2007,pp 1856-1865
2012Interdomain orientation of cardiac Troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact stateGell, David; Liew, Chu; Mackay, Joel; Brown, Louise J; Cordina, Nicole; Fajer, Piotr; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceInterdomain orientation of cardiac Troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state, Protein Science, vol.21, 9, 2012,pp 1376-1387
2004Loss Of Alpha-Hemoglobin-Stabilizing Protein Impairs Erythropoiesis And Exacerbates Beta-ThalassemiaGell, David; Mackay, Joel; Adachi, Kazuhiko; Foster-Brown, Linda; Gow, Andrew J; Katein, Anne M; Kihm, Anthony J; Kong, Yi; Louden, Calvert S; Weiss, Mitchell J; Yu, Xiang; Zhou, Suiping; Molecular & Microbial Bioscien; Molecular & Microbial BioscienLoss Of Alpha-Hemoglobin-Stabilizing Protein Impairs Erythropoiesis And Exacerbates Beta-Thalassemia, Journal of Clinical Investigation, vol.114,(10),2004,pp 1457-1466
2004Molecular Mechanism Of AHSP-Mediated Stabilization Of A-HemoglobinArmstrong, Robert; Gell, David; Lay, Peter; Lee, Christopher; Mackay, Joel; Rich, Anne; Feng, Liang; Gow, Andrew J; Gu, Lichuan; Hu, Min; Kong, Yi; Li, Jianqing; Shi, Yigong; Weiss, Mitchell J; Yan, Nieng; Zhou, Suiping; Chemistry; Molecular & Microbial Bioscien; Chemistry; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; ChemistryMolecular Mechanism Of AHSP-Mediated Stabilization Of A-Hemoglobin, Cell, vol.119,(5),2004,pp 629-640
2002A new zinc binding fold underlines the versatility of zinc binding modules in protein evolutionCrossley, Paul (Merlin); Gell, David; Kwan, Ann; Mackay, Joel; Matthews, Jacqueline; Newton, Anthea; Sharpe, Belinda; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceA new zinc binding fold underlines the versatility of zinc binding modules in protein evolution, Structure, vol.10, 5,pp 639-648
2006A Novel Haem-binding Interface in the 22 kDa Haem-binding Protein p22HBP.Gell, David; Gorman, Daniel; Liew, Chu; Mackay, Joel; Westman, Belinda; Liew, John J; Weiss, Mitchell J; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceA Novel Haem-binding Interface in the 22 kDa Haem-binding Protein p22HBP., Journal of Molecular Biology, vol.362,(2),2006,pp 287-297
2005Role of Alpha Hemoglobin-Stabilizing Protein in Normal Erythropoiesis and {beta}-Thalassemia.Gell, David; Mackay, Joel; Feng, Liang; Gow, Andrew J; Shi, Yigong; Weiss, Mitchell J; Zhou, Suiping; School of Molecular Bioscience; School of Molecular BioscienceRole of Alpha Hemoglobin-Stabilizing Protein in Normal Erythropoiesis and {beta}-Thalassemia., New York Academy of Sciences. Annals, vol.1054,(N/A),2005,pp 103-117
2005Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem.Gell, David; Mackay, Joel; Feng, Liang; Gow, Andrew J; Gu, Lichuan; Shi, Yigong; Weiss, Mitchell J; Zhou, Suiping; Molecular & Microbial Bioscien; Molecular & Microbial BioscienStructure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem., Nature, vol.435,(7042),2005,pp 697-701
2010Two-state conformational equilibrium in the Par-4 leucine zipper domainGell, David; Mackay, Joel; Claridge, Jolyon K; Dutta, Kaushik; Edwards, Patrick J.; Libich, David; Pascal, Steven M.; Schwalbe, Martin; Venugopal, Hariprasad; School of Molecular Bioscience; School of Molecular BioscienceTwo-state conformational equilibrium in the Par-4 leucine zipper domain, Proteins: Structure, Function, and Bioinformatics, vol.78, 11,pp 2433-2449