Browsing by Author Friedrich, Michael

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Issue DateTitleAuthor(s)Citation
2016Amyloid Plaque in the Human Brain Can Decompose from A?(1-40/1-42) by Spontaneous Nonenzymatic ProcessesLyons, Brian; Friedrich, Michael; Raftery, Mark; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.Amyloid Plaque in the Human Brain Can Decompose from A?(1-40/1-42) by Spontaneous Nonenzymatic Processes, Analytical Chemistry, vol.88, 5, 2016,pp 2675-2684
2012Degradation of an Old Human Protein: Age-Dependent Cleavage of γS-Crystallin Generates a Peptide that Binds to Cell MembranesTruscott, Roger; Friedrich, Michael; Lam, Jackson; Central Clinical School: Clinical Ophthal & Eye HealthDegradation of an Old Human Protein: Age-Dependent Cleavage of γS-Crystallin Generates a Peptide that Binds to Cell Membranes, Journal of Biological Chemistry, vol.287, 46, 2012,pp 39012-39020
2008Free and bound water in normal and cataractous human lensesFriedrich, Michael; Heys, Karl; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthFree and bound water in normal and cataractous human lenses, Investigative Ophthalmology & Visual Science, vol.49,(5),2008,pp 1991-1997
2012Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?Davies, Michael; Truscott, Roger John Willis; David, Larry; Friedrich, Michael; Hooi, Michelle; Jamie, Joanne F.; Lyons, Brian; Mizdrak, Jasminka; Wilmarth, Phillip; Central Clinical School: Heart Research Institute; Central Clinical School: Clinical Ophthal & Eye HealthIs protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?, Experimental Eye Research, vol.99, 1, 2012,pp 48-54
2010Large scale binding of {alpha}-crystallin to cell membranes of aged normal human lenses; a phenomenon that can be induced by mild thermal stressFriedrich, Michael; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthLarge scale binding of {alpha}-crystallin to cell membranes of aged normal human lenses; a phenomenon that can be induced by mild thermal stress, Investigative Ophthalmology & Visual Science, vol.51, 10,pp 5145-5152
2009Membrane association of proteins in the aging human lens: profound changes take place in the 5th decade of lifeFriedrich, Michael; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthMembrane association of proteins in the aging human lens: profound changes take place in the 5th decade of life, Investigative Ophthalmology & Visual Science, vol.50, 10,pp 4786-4793
2012Molecular signatures of long-lived proteins: autolytic cleavage adjacent to serine residuesFriedrich, Michael; Lyons, Brian; Truscott, Roger; Aquilina, John; McArthur, Jason D.; Song, Xiaomin; Su, Shih-Ping; Xavier, Dylan; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthMolecular signatures of long-lived proteins: autolytic cleavage adjacent to serine residues, Aging Cell, vol.11, 6, 2012,pp 1125-1127
2007Presbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibilityFriedrich, Michael; Heys, Karl; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthPresbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibility, Aging Cell, vol.6,(6),2007,pp 807-815
2010Sphingolipid distribution changes with age in the human lensFriedrich, Michael; Truscott, Roger; Blanksby, Stephen J; Deeley, Jane M; Hankin, Joseph; Mitchell, Todd W; Murphy, Robert; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthSphingolipid distribution changes with age in the human lens, Journal of Lipid Research, vol.51, N/A,pp 2753-2760