Browsing by Author Easterbrook-Smith, Simon

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Issue DateTitleAuthor(s)Citation
2005The acute phase protein haptoglobin is a mammalian extracellular chaperone with an action similar to clusterin.Easterbrook-Smith, Simon; Henriques, C; Rybchyn, Mark; Wilson, Mark R; Yerbury, Justin J.; Molecular & Microbial Bioscien; Central Clinical School: Medicine; School of Medical Sciences: PhysiologyThe acute phase protein haptoglobin is a mammalian extracellular chaperone with an action similar to clusterin., Biochemistry 2005, vol.44,(32),2005,pp 10914-10925
2007Characterization of the Binding of Cu(II) and Zn(II) to Transthyretin: Effects on Amyloid FormationEasterbrook-Smith, Simon; Wilkinson-White, Lorna; Molecular & Microbial Bioscien; Molecular & Microbial BioscienCharacterization of the Binding of Cu(II) and Zn(II) to Transthyretin: Effects on Amyloid Formation, Biochemistry, vol.46,(31),2007,pp 9123-9132
2002Clusterin is an extracellular chaperone that specifically interacts with slowly aggregating proteins on their off-folding pathwayEasterbrook-Smith, Simon; Carver, John A; Poon, Stephen; Treweek, Teresa M; Wilson, Mark R; Molecular & Microbial BioscienClusterin is an extracellular chaperone that specifically interacts with slowly aggregating proteins on their off-folding pathway, FEBS Letters, vol.513,(2-3),2002,pp 259-266
2008A dye-binding assay for measurement of the binding of Cu(II) to proteinsEasterbrook-Smith, Simon; Wilkinson-White, Lorna; School of Molecular Bioscience; School of Molecular BioscienceA dye-binding assay for measurement of the binding of Cu(II) to proteins, Journal of Inorganic Biochemistry, vol.102, N/A,pp 1831-1838
2007Effects of glycosylation on the structure and function of the extracellular chaperone clusterinEasterbrook-Smith, Simon; Aquilina, J Andrew; Jacobsen, Christian; Moestrup, Søren Kragh; Murphy-Durland, Danielle; Stewart, Elise M.; Wilson, Mark R; Molecular & Microbial BioscienEffects of glycosylation on the structure and function of the extracellular chaperone clusterin, Biochemistry, vol.46,(5),2007,pp 1412-1422
2002Evidence that clusterin has discrete chaperone and ligand binding sitesEasterbrook-Smith, Simon; Carver, John A; Lakins, Johnathon; Poon, Stephen; Tenniswood, Martin P R; Wilson, Mark R; School of Molecular BioscienceEvidence that clusterin has discrete chaperone and ligand binding sites, Biochemistry, vol.41, 1,pp 282-291
2002Mildly acidic pH activates the extracellular molecular chaperone clusterinEasterbrook-Smith, Simon; Pankhurst, Gregory; Rybchyn, Mark; Carver, John A; Poon, Stephen; Wilson, Mark R; Molecular & Microbial Bioscien; Biochemistry; School of Medical Sciences: PhysiologyMildly acidic pH activates the extracellular molecular chaperone clusterin, Journal of Biological Chemistry, vol.277,(42),2002,pp 39532-39540
2012Serum albumin prevents protein aggregation and amyloid formation and retains chaperone-like activity in the presence of physiological ligandsEasterbrook-Smith, Simon; Finn, Thomas; Nunez, Andrea; Sunde, Margaret; Molecular Bioscience; Molecular Bioscience; Northern Clinical School: Medicine; Molecular BioscienceSerum albumin prevents protein aggregation and amyloid formation and retains chaperone-like activity in the presence of physiological ligands, Journal of Biological Chemistry, vol.287, 25, 2012,pp 21530-21540
2002Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterinEasterbrook-Smith, Simon; Hatters, Danny M; Howlett, Geoffrey J; Wilson, Mark R; Molecular & Microbial BioscienSuppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin, The F E B S Journal (Print Edition), vol.269,(11),2002,pp 2789-2794