Browsing by Author Cowan, Peter J

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Issue DateTitleAuthor(s)Citation
2013Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID modelHawthorne, Wayne; O'Connell, Philip; Phillips, Peta; Brady, Jamie L; Cowan, Peter J; d'Apice, Anthony J. F.; Hancock, Manuela; Harrison, Leonard; Kitsoulis, Susie; Lahoud, Mireille; Lew, Andrew; Sutherland, Robyn M; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID model, Xenotransplantation, vol.20, 2, 2013,pp 100-109
2007Blockade of the Passive Cell Death Pathway Does Not Prevent Tolerance Induction to Islet GraftsLehnert, Anne; O'Connell, Philip; Cowan, Peter J; d'Apice, Anthony J. F.; Murray-Segal, Lisa; REPROGEN; Western Clinical School: Westmead Millennium InstituteBlockade of the Passive Cell Death Pathway Does Not Prevent Tolerance Induction to Islet Grafts, Transplantation 2005, vol.83,(5),2007,pp 653-655
2015Clonidine inhibits anti-non-Gal IgM xenoantibody elicited in multiple pig-to-primate modelsHawthorne, Wayne; O'Connell, Philip; Cowan, Peter J; D'Apice, Anthony J F; Kearns-Jonker, Mary; Nottle, Mark B.; Salvaris, Evelyn J; Stewart, John; Tarantal, Alice; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical ResClonidine inhibits anti-non-Gal IgM xenoantibody elicited in multiple pig-to-primate models, Xenotransplantation, vol.22, 6, 2015,pp 413-426
2014Control of IBMIR in Neonatal Porcine Islet Xenotransplantation in BaboonsHawthorne, Wayne; Hu, Min; O'Connell, Philip; Barlow, H; Burns, H; Cowan, Peter J; d’Apice, Anthony J.F.; Hawkes, J; Lew, Andrew; Liuwantara, David; Nottle, Mark B.; Peirce, S B; Phillips, P; Robson, Simon; Salvaris, Evelyn J; Stewart, A B; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteControl of IBMIR in Neonatal Porcine Islet Xenotransplantation in Baboons, American Journal of Transplantation, vol.14, 6, 2014,pp 1300-1309
2013Differential migration of passenger leukocytes and rapid deletion of naive alloreactive CD8 T cells after mouse liver transplantation.Benseler, Volker; Bertolino, Patrick; Bishop, George (Alex); Bowen, David; McCaughan, Geoffrey; McGuffog, Claire; Sierro, Frederic; Tay, Szun; Cowan, Peter J; Dwyer, Karen; Lu, Bo; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryDifferential migration of passenger leukocytes and rapid deletion of naive alloreactive CD8 T cells after mouse liver transplantation., Liver Transplantation, vol.19, 11, 2013,pp 1224-1235
2007Evaluation of promoters for driving efficient transgene expression in neonatal porcine isletsHawthorne, Wayne; O'Connell, Philip; Brady, Jamie L; Cowan, Peter J; Jhala, Guarang; Kay, Thomas W; Lew, Andrew; Londrigan, Sarah L; Sutherland, Robyn M; Thomas, Helen E; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteEvaluation of promoters for driving efficient transgene expression in neonatal porcine islets, Xenotransplantation, vol.14,(2),2007,pp 119-125
2004Fate Of Alphagal +/+ Pancreatic Islet Grafts After Transplantation Into Alphagal Knockout Mice.Chandra, Abhilash; Lehnert, Anne; O'Connell, Philip; Walters, Stacey; Wong, Jeferey; Cowan, Peter J; d'Apice, Anthony J. F.; Gock, Hilton; Murray-Segal, Lisa; Salvaris, Evelyn; Western Clinical School: Westmead Millennium Institute; REPROGEN; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium InstituteFate Of Alphagal +/+ Pancreatic Islet Grafts After Transplantation Into Alphagal Knockout Mice., Xenotransplantation, vol.11,(4),2004,pp 323-331
2010In Situ Protection Against Islet Allograft Rejection by CTLA4Ig TransductionO'Connell, Philip; Brady, Jamie L; Carrington, Emma M.; Cowan, Peter J; d’Apice, Anthony J.F.; Lew, Andrew; Londrigan, Sarah L; Sutherland, Robyn M; Zhan, Yifan; Western Clinical School: Westmead Millennium InstituteIn Situ Protection Against Islet Allograft Rejection by CTLA4Ig Transduction, Transplantation, vol.90, 9,pp 951-957
2005Overexpression of glutathione peroxidase with two isoforms of superoxide dismutase protects mouse islets from oxidative injury and improves islet graft function.Chandra, Abhilash; Collins, John; O'Connell, Philip; Stokes, Rebecca; Walters, Susan; Cowan, Peter J; D'Apice, Anthony J F; Fisicaro, Nell; Johnson, Lucinda E A; Lepore, Diana A; Murray-Segal, Lisa J; Mysore, Tharun B; Salvaris, Evelyn J; Shinkel, Trixie A; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Anaesthesia; Western Clinical School: Westmead Millennium Institute; Vet Science Faculty; Central Clinical School: SurgeryOverexpression of glutathione peroxidase with two isoforms of superoxide dismutase protects mouse islets from oxidative injury and improves islet graft function., Diabetes, vol.54,(7),2005,pp 2109-16
2014Preclinical screening for acute toxicity of therapeutic monoclonal antibodies in a hu-SCID modelHawthorne, Wayne; O'Connell, Philip; Brady, Jamie L; Cowan, Peter J; Goodman, David; Harrison, Leonard; Lew, Andrew; Sutherland, Robyn M; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstitutePreclinical screening for acute toxicity of therapeutic monoclonal antibodies in a hu-SCID model, Clinical & Translational Immunology, vol.3, 12, 2014,pp 1-7
2007Production of homozygous alpha-1,3-galactosyltransferase knockout pigs by breeding and somatic cell nuclear transfer.O'Connell, Philip; Ashman, Rodney J; Beebe, L F S; Cowan, Peter J; d'Apice, Anthony J. F.; Fisicaro, Nella; Harrison, Sharon; McIlfatrick, Stephen M; Nottle, Mark B; Pommey, Sandra; Salvaris, Evelyn J; Western Clinical School: Westmead Millennium InstituteProduction of homozygous alpha-1,3-galactosyltransferase knockout pigs by breeding and somatic cell nuclear transfer., Xenotransplantation, vol.14,(4),2007,pp 339-344
2017Regulation of Clinical Xenotransplantation-Time for a ReappraisalHawthorne, Wayne; Ahn, Curie; Azimzadeh, Agnes; Buhler, Leo H; Cooper, David K C; Cowan, Peter J; Denner, Joachim; Fishman, Jay; Hering, Bernhard; Kobayashi, Takaaki; Mohiuddin, Muhammad; Pierson, Richard N.; Sachs, David; Westmead Clinical School: SurgeryRegulation of Clinical Xenotransplantation-Time for a Reappraisal, Transplantation, vol.101, 8, 2017,pp 1766-1769
2012Regulatory T cells participate in CD39-mediated protection from renal injuryAlexander, Stephen; Harris, David; Hu, Min; Lee, Vincent; Wang, Ya; Wang, Yiping; Wang, Yuan; Zheng, Guoping; Cowan, Peter J; Dwyer, Karen; McRae, Jennifer; Polhill, Tania; Robson, Simon; Unwin, Robert; Zhang, Geoff Yu; Children's Hospital Westmead: Paediatrics & Child Health; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Children's Hospital Westmead: Paediatrics & Child Health; Western Clinical School: Westmead Millennium Institute; Children's Hospital Westmead: Paediatrics & Child Health; Western Clinical School: Medicine (Westmead)Regulatory T cells participate in CD39-mediated protection from renal injury, European Journal of Immunology, vol.42, 9, 2012,pp 2441-2451
2014Rhesus monkeys and baboons develop clotting factor VIII inhibitors in response to porcine endothelial cells or isletsHawthorne, Wayne; O'Connell, Philip; Cowan, Peter J; D'Apice, Anthony J F; Kearns-Jonker, Mary; Nottle, Mark B.; Salvaris, Evelyn J; Stewart, John; Tarantal, Alice; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteRhesus monkeys and baboons develop clotting factor VIII inhibitors in response to porcine endothelial cells or islets, Colorectal Disease, vol.21, 4, 2014,pp 341-352
2014The role of adenosine receptors A2A and A2B signaling in renal fibrosisAlexander, Stephen; Cowan, Peter J; Dwyer, Karen; Roberts, V; Robson, Simon; Childrens Hospital Westmead: Paediatrics & Child HealthThe role of adenosine receptors A2A and A2B signaling in renal fibrosis, Kidney International, vol.86, 4, 2014,pp 685-692
2013Transplantation of Xenogeneic Islets: Are We There Yet?Hawthorne, Wayne; O'Connell, Philip; Yi, Shounan; Cowan, Peter J; Lew, Andrew; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteTransplantation of Xenogeneic Islets: Are We There Yet?, Current Diabetes Reports, vol.13, 5, 2013,pp 687-694
2011Versatile co-expression of graft-protective proteins using 2A-linked cassettesO'Connell, Philip; Brady, Jamie L; Cowan, Peter J; d'Apice, Anthony J. F.; Fisicaro, Nella; Lew, Andrew; Londrigan, Sarah L; Nottle, Mark B.; Robson, Simon; Salvaris, Evelyn J; Western Clinical School: Westmead Millennium InstituteVersatile co-expression of graft-protective proteins using 2A-linked cassettes, Xenotransplantation, vol.18, 2, 2011,pp 121-130
2014Xenoantibody response to porcine islet cell transplantation using GTKO, CD55, CD59, and fucosyltransferase multiple transgenic donorsHawthorne, Wayne; O'Connell, Philip; Chen, Yan; Cowan, Peter J; dApice, Anthony; Gunthart, Mirja; Kearns-Jonker, Mary; Nottle, Mark B.; Salvaris, Evelyn J; Stewart, John; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteXenoantibody response to porcine islet cell transplantation using GTKO, CD55, CD59, and fucosyltransferase multiple transgenic donors, Xenotransplantation, vol.21, 3, 2014,pp 244-253