Browsing by Author Collyer, Charles

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Issue DateTitleAuthor(s)Citation
2005Binding of Porphyromonas gingivalis gingipains to human CD4(+) T cells preferentially down-regulates surface CD2 and CD4 with little affect on co-stimulatory molecule expression.Chapple, Cheryl; Collyer, Charles; Hunter, Neil; Yun, P; DeCarlo, Arthur A.; Dentistry Faculty; Molecular & Microbial Bioscien; Dentistry Faculty; Dentistry FacultyBinding of Porphyromonas gingivalis gingipains to human CD4(+) T cells preferentially down-regulates surface CD2 and CD4 with little affect on co-stimulatory molecule expression., Microbial pathogenesis, vol.38,(2-3),2005,pp 85-96
2015Compensatory Stabilizing Role of Surface Mutations During the Directed Evolution of Dienelactone Hydrolase for Enhanced ActivityCollyer, Charles; Ollis, David; Porter, Joanne L; Molecular BioscienceCompensatory Stabilizing Role of Surface Mutations During the Directed Evolution of Dienelactone Hydrolase for Enhanced Activity, Protein Journal, vol.34, 1, 2015,pp 82-89
2010Correlation of Active Site Metal Content in Human Diamine Oxidase with Trihydroxyphenylalanine Quinone Cofactor BiogenesisCollyer, Charles; Guss, Jules Mitchell; McGrath, Aaron; Caradoc-Davies, Tom; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceCorrelation of Active Site Metal Content in Human Diamine Oxidase with Trihydroxyphenylalanine Quinone Cofactor Biogenesis, Biochemistry, vol.49, 38,pp 8316-8324
2014Crystallization of dienelactone hydrolase in two space groups: structural changes caused by crystal packingCollyer, Charles; Carr, Paul D.; Ollis, David L.; Porter, Joanne L; Molecular BioscienceCrystallization of dienelactone hydrolase in two space groups: structural changes caused by crystal packing, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, vol.70, 7, 2014,pp 884-889
2004Crystallization Of Gcna, An N-Acetyl-β-D-Glucosaminidase, From Streptococcus GordoniiCollyer, Charles; Graham, Stephen; Guss, Jules Mitchell; Harty, Derek; Hunter, Neil; Langley, David; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Dentistry Faculty; Dentistry Faculty; Molecular & Microbial BioscienCrystallization Of Gcna, An N-Acetyl-β-D-Glucosaminidase, From Streptococcus Gordonii, Acta Crystallographica. Section D: Biological Crystallog, vol.D60,(N/A),2004,pp 1910-1911
2003Crystallization of hamster dihydroorotase: involvement of a disulfide-linked tetrameric formChristopherson, Richard; Collyer, Charles; Guss, Jules Mitchell; Huang, Danny; Maher, Megan; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceCrystallization of hamster dihydroorotase: involvement of a disulfide-linked tetrameric form, Acta Crystallographica. Section D: Biological Crystallography, vol.59,(2),2003,pp 381-384
2015Directed Evolution of New and Improved Enzyme Functions Using an Evolutionary Intermediate and Multi-directional SearchCollyer, Charles; Boon, Priscilla; Huber, Thomas; Murray, Tracy P.; Ollis, David L.; Porter, Joanne L; Molecular BioscienceDirected Evolution of New and Improved Enzyme Functions Using an Evolutionary Intermediate and Multi-directional Search, ACS Chemical Biology, vol.10, N/A, 2015,pp 611-621
2005A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing.Clifton-Bligh, Roderick; Collyer, Charles; Conigrave, Arthur; Culverston, Emma; Franks, Alison; Mun, Hee-Chang; Northern Clinical School: Medicine; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; School of Medical Sciences: Physiology; Molecular & Microbial Bioscien; Molecular & Microbial BioscienA double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing., Journal of Biological Chemistry, vol.280,(32),2005,pp 29067-29072
2003Enhancement of Th2 pathways and direct activation of B cells by the gingipains of Porphyromonas gingivalisCollyer, Charles; Yun, Lu; DeCarlo, Arthur; Hunter, Neil; School of Molecular Bioscience; MedicineEnhancement of Th2 pathways and direct activation of B cells by the gingipains of Porphyromonas gingivalis, Clinical and Experimental Immunology, vol.134,(2),2003,pp 295-302
2003Feasibility of an HA2 domain-based periodontitis vaccineCollyer, Charles; Langley, David; DeCarlo, A A; Huang, Y; Katz, J; Molecular & Microbial Bioscien; Molecular & Microbial BioscienFeasibility of an HA2 domain-based periodontitis vaccine, Infection and Immunity, vol.71,(1),2003,pp 562-566
2012First Steps Towards Quantum Refinement of Protein X-ray StructuresCollyer, Charles; Goerigk, Lars; Reimers, Jeffrey; Falklof, Olle; Molecular Bioscience; Chemistry; ChemistryFirst Steps Towards Quantum Refinement of Protein X-ray Structures in Quantum Simulations of Materials and Biological Systems, Springer, 2012, pp. 87-120
2017High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetateAkladios, Fady; Church, William; Collyer, Charles; Gorrell, Mark; Nadvi, Naveed; Park, Joo Hong; Salam, Noeris; Kapoor, Vimal; Chemistry; Pharmacy; School of Molecular Bioscience (SMB); Central Clinical School: Centenary Institute; RADS - Research Analytics & Data Strategy; Central Clinical School: Medicine; PharmacyHigh resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate, Protein Science, vol.26, 4, 2017,pp 727-736
2004Humoral Responses To Porphyromonas Gingivalis Gingipain Adhesin Domains In Subjects With Chronic PeriodontitisCollyer, Charles; DeCarlo, Arthur; Hunter, Neil; Langley, David; Nguyen, Ky-Anh; Paramaesvaran, M; School of Molecular Bioscience; Dentistry Faculty; Dentistry Faculty; School of Molecular Bioscience; Dentistry Faculty; Dentistry FacultyHumoral Responses To Porphyromonas Gingivalis Gingipain Adhesin Domains In Subjects With Chronic Periodontitis, Infection and Immunity, vol.72,(3),2004,pp 1374-1382
2017Insights into an evolutionary strategy leading to antibiotic resistanceCollyer, Charles; Hou, Chun-Feng; Liu, Jian-wei; Mitic, Natasa; Ollis, David; Pedroso, Marcelo; Schenk, Gerhard; School of Molecular Bioscience (SMB)Insights into an evolutionary strategy leading to antibiotic resistance, Scientific Reports, vol.7, N/A, 2017,pp 40357-N/A
2005Kinetic analysis of the L-ornithine transcarbamoylase from Pseudomonas savastanoi pv. phaseolicola that is resistant to the transition state analogue (R)-N delta-(N'-sulfodiaminophosphinyl)-L-ornithine.Collyer, Charles; Cleland, W Wallace; Mitchell, Robin; Reinhardt, Laurie A; Templeton, Matthew D; School of Molecular BioscienceKinetic analysis of the L-ornithine transcarbamoylase from Pseudomonas savastanoi pv. phaseolicola that is resistant to the transition state analogue (R)-N delta-(N'-sulfodiaminophosphinyl)-L-ornithine., Biochemistry, vol.44,(11),2005,pp 4408-15
2011The modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalisChurch, William; Collyer, Charles; Gamsjaeger, Roland; Hunter, Neil; Jeffries, Cy; Langley, David; Li, Nan; Yun, Peter; Pharmacy; Molecular Bioscience; Molecular Bioscience; Dentistry Faculty; Molecular Bioscience; Molecular Bioscience; Molecular BioscienceThe modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalis, Molecular Microbiology, vol.81, 5, 2011,pp 1358-1373
2002Modulation of an interleukin-12 and interferon gamma synergistic feedback regulatory cycle of T-cell/monocyte co-cultures by Porphyromonas gingivalis lipopolysaccharide in the absence or presence of cysteine proteinasesCollyer, Charles; Hunter, Neil; Yun, P; DeCarlo, Arthur; School of Molecular Bioscience; Dentistry Faculty; Dentistry FacultyModulation of an interleukin-12 and interferon gamma synergistic feedback regulatory cycle of T-cell/monocyte co-cultures by Porphyromonas gingivalis lipopolysaccharide in the absence or presence of cysteine proteinases, Infection and Immunity, vol.70, 10,pp 5695-5705
2010A new crystal form of human diamine oxidaseCollyer, Charles; Guss, Jules Mitchell; McGrath, Aaron; Dooley, David M.; Hilmer, Kim; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceA new crystal form of human diamine oxidase, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, vol.66, 2,pp 137-142
2010A new crystal form of human vascular adhesion protein 1Collyer, Charles; Ernberg, Karin; Guss, Jules Mitchell; McGrath, Aaron; Adams, Timothy E.; McDonald, Ian; Newman, Janet; Peat, Thomas; Pham, Tam; Xiao, Xiaowen; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceA new crystal form of human vascular adhesion protein 1, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, vol.66, Pt 12,pp 1572-1578
2009Porphyrin-linked nitroimidazole antibiotics targeting Prophyromonas gingivalisCollyer, Charles; Crossley, Maxwell; Hunter, Neil; Simpkins, Grace; Yap, Benjamin; Molecular & Microbial Bioscien; Chemistry; Dentistry Faculty; Chemistry; ChemistryPorphyrin-linked nitroimidazole antibiotics targeting Prophyromonas gingivalis, Organic & Biomolecular Chemistry, vol.7,(14),2009,pp 2855-2863